Ep 162 Allergies Part 2: Shots, pills, & pens

Ep 162 Allergies Part 2: Shots, pills, & pens

Yes, the world may be out to get us with allergens around every corner, but we’ve got some tricks up our sleeve to help us cope. Our allergy treatment toolkit includes an impressive suite of tools, and in the second episode of our two-part series on allergies, we focus on three in particular: antihistamine medications, allergy shots, and the epinephrine auto-injector (aka the EpiPen). We take you through how exactly each of these work, trace their development from concept to product, and highlight some of the most promising areas of allergy treatment research today. Have you ever wondered why we have so many different types of antihistamines? Or thought about what the Cold War has to do with the EpiPen? Then this is the episode for you.

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Ep 59 Thalidomide: Justice Delayed, Justice Denied

Ep 59 Thalidomide: Justice Delayed, Justice Denied

The story of thalidomide is often employed as a cautionary tale - why testing a drug’s safety during pregnancy is crucial or why it’s important to choose the right animal models. Or it’s framed as a s...

29 Syys 20201h 32min

Ep 58 Guinea worm: (Almost) Ancient History

Ep 58 Guinea worm: (Almost) Ancient History

You’ve heard about smallpox, and you’ve learned about rinderpest. Now it’s time to meet what may be the third disease to ever be eradicated: dracunculiasis, also known as Guinea worm disease. In this ...

15 Syys 20201h 9min

Ep 57 Herpes: Stop the STIgma

Ep 57 Herpes: Stop the STIgma

The harm caused by herpes simplex viruses (HSV) 1 & 2 often arises not from the pathology of the viruses themselves but rather from the stigma and shame associated with a positive diagnosis. In this e...

1 Syys 20201h 25min

Ep 56 Sickle Cell Disease: Invisible Illness, Enduring Strength

Ep 56 Sickle Cell Disease: Invisible Illness, Enduring Strength

Neglected and ignored by the medical establishment throughout most of its history, sickle cell disease remains one of the most common (and commonly misunderstood) genetic conditions in the world. In t...

18 Elo 20201h 59min

Ep 55 Rocky Mountain spotted fever: The tick must be destroyed!

Ep 55 Rocky Mountain spotted fever: The tick must be destroyed!

Despite what its name might suggest, the story of Rocky Mountain spotted fever (RMSF) takes us far beyond the jagged, snow-capped peaks of the western range. From the Bitterroot Valley to southeastern...

4 Elo 20201h 47min

Ep 54 Wake Up and Smell the Caffeine

Ep 54 Wake Up and Smell the Caffeine

Are you one of the billions of people around the world who starts your day with a freshly brewed and deliciously aromatic cup of coffee or tea or maybe even hot chocolate? Or are you caffeine-avoidant...

21 Heinä 20201h 23min

Ep 53 Radiation: X-Ray Marks the Spot

Ep 53 Radiation: X-Ray Marks the Spot

“I have discovered something interesting, but I do not know whether or not my observations are correct.” With these words, Wilhelm Röntgen introduced the world to an invisible power, a power which wou...

7 Heinä 20201h 53min

Ep 52 Rinderpest: Moo Cows, Moo Problems

Ep 52 Rinderpest: Moo Cows, Moo Problems

The second disease ever to be eradicated, rinderpest could be the most devastating and notorious infection you never knew existed. Though its name means “cattle plague”, the deadly rinderpest virus in...

23 Kesä 20201h 20min

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