Episode 288: 287. A New FDA Approved Drug for Chronic Rhinosinusitis

Episode 288: 287. A New FDA Approved Drug for Chronic Rhinosinusitis

recipients were more likely than placebo recipients to report much or very much improvement (55% vs. 25%) which isn’t shocking because half of the people were not getting medicine

they also report that the medication arm had improvement on CT imaging of the sinuses which also seems like another Duh moment as I am sure it was better than nothing

my concern is this new drug or deliver of the drug is a cash price of about 800-1000 per month while just simple fluticasone is around 10$ a month. I think for now stick with the normal 10$ fluticasone but if there is no success and continue to have severe symptoms then maybe consider this if they have good insurance

bottom line is there is a new drug out there that is basically fluticasone in a fancy delivery device.. for almost all my patients and family members they will be getting regular fluticasone not this fancy delivery device that goes but the name XHANCE

https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S221321982301365X?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS221321982301365X%3Fshowall%3Dtrue&referrer=https:%2F%2Fwww.jwatch.org%2F

Jaksot(387)

Episode 353: 252. 2.4 Million to Prevent 4 Hospitalizations!

Episode 353: 252. 2.4 Million to Prevent 4 Hospitalizations!

Packer M et al. Tirzepatide for heart failure with preserved ejection fraction and obesity. N Engl J Med 2024 Nov 16; [e-pub].https://doi.org/10.1056/NEJMoa2410027  In the industry-funded SUMMIT trial...

13 Joulu 202411min

Episode 352: 251. Safety of Triptans in Patients Who Have or Are at High Risk for Cardiovascular Disease

Episode 352: 251. Safety of Triptans in Patients Who Have or Are at High Risk for Cardiovascular Disease

Wang Z et al. Safety of triptans in patients who have or are at high risk for cardiovascular disease: A target trial emulation. Mayo Clin Proc 2024 Nov; 99:1722. (https://doi.org/10.1016/j.mayocp.2024...

12 Joulu 20246min

Episode 351: 250. STROKE part 3 CME

Episode 351: 250. STROKE part 3 CME

STROKE part 3 CME

29 Marras 20249min

Episode 350: 249. STROKE - LA closure, alteplase vs tenecteplase, and thrombectomy

Episode 350: 249. STROKE - LA closure, alteplase vs tenecteplase, and thrombectomy

CME FOR FREEE

27 Marras 202417min

Episode 349: 248. Stroke- UIA, CHAD-VASC, HAS-BLED, SPARC, PFO

Episode 349: 248. Stroke- UIA, CHAD-VASC, HAS-BLED, SPARC, PFO

CME --- Stroke- UIA, CHAD-VASC, HAS-BLED, SPARC, PFO

26 Marras 202436min

Episode 348: 247. Early diagnostic paracentesis improves outcomes of hospitalized patients with cirrhosis and ascites

Episode 348: 247. Early diagnostic paracentesis improves outcomes of hospitalized patients with cirrhosis and ascites

Beran A et al. Early diagnostic paracentesis improves outcomes of hospitalized patients with cirrhosis and ascites: A systematic review and meta-analysis. Am J Gastroenterol 2024 Nov; 119:2259. (https...

22 Marras 20246min

Episode 347: 246.  Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk

Episode 347: 246. Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk

Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA Internal Medicine | JAMA Network  In a randomized ...

21 Marras 20248min

Episode 346: 245. Duration of benefit and risk of dual antiplatelet therapy after mild ischemic stroke

Episode 346: 245. Duration of benefit and risk of dual antiplatelet therapy after mild ischemic stroke

And now a secondary analysis of the trial focused on the timing of major ischemic events and the potential tradeoffs of benefits and risks,------ maybe there is magic sauce where the benefit is drasti...

20 Marras 20247min

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