Episode 424: 431. Gout should we treat to a number? Is Co-testing needed?
https://www.sciencedirect.com/science/article/abs/pii/S2665991326000342?via%3Dihublancet rheumatology A treat-to-target strategy versus symptom-driven management of gout in the Netherlands (GO TEST Ov...
14 Huhti 18min
Episode 423: 430. Hormone Replacement Therapy and the Black Box Warning
Let’s rewind to the early 2000s. Flip phones were cool, low-rise jeans were a crime, and the Women’s Health Initiative—WHI—dropped what became the medical equivalent of a headline: “Hormone Therapy In...
24 Maalis 12min
Episode 422: 429. Rivaroxaban vs Apixaban = The Battle of the Blood Thinners!
— rivaroxaban versus apixaban.Yes, folks, this is The Battle of the Blood Thinners!And spoiler alert — one of them came out looking like the overachiever in a safety class... while the other probably ...
20 Maalis 9min
Episode 421: 428. Asthma and Stroke --- A breathless combination
Minocycline in Acute Ischemic Stroke (EMPHASIS trial)A multicenter, double-blind RCT in China studied 1,724 patients with acute ischemic stroke treated within 72 hours of onset. Patients received eith...
13 Maalis 16min
Episode 420: 427. Kawasaki disease-no, not the motorcycle company
Today, we're talking about Kawasaki disease-no, not the motorcycle company, though sometimes treating it does feel like trying to ride one at full speed through uncertainty.For decades, high-dose aspi...
11 Maalis 7min
Episode 419: 426. Go Big or Go Partial? The Knee Replacement Showdown
Setting the stagePicture this: your knee is like a three-room apartment. You've got a medial room, a lateral room, and a patellofemoral room. In isolated anteromedial osteoarthritis, just one room is ...
10 Maalis 11min
Episode 418: 425. Triptan initiation and cerebrovascular events
Kalapura C, et al. Triptan initiation and cerebrovascular events in patients with migraine: A nationwide cohort study. J Am Heart Assoc 2026 Feb 17; 15:e043409. DOI: 10.1161/JAHA.125.043409. Today, w...
6 Maalis 6min
Episode 417: 424. GLP1 and NAION
Li H-Y, et al. GLP-1 receptor agonists and risk of optic nerve or vision-threatening events in patients with type 2 diabetes or cardiometabolic diseases: A meta-analysis of randomized controlled trial...
5 Maalis 8min
