Episode 294: 293. Should GLP-1 Agonist be Held Prior to Procedure or Surgery?

• glucagon-like peptide-1 (GLP-1) receptor agonists can delay gastric emptying, the American Society of Anesthesiologists (ASA) say For patients on daily dosing consider holding GLP-1 agonists on the day of the procedure/surgery. For patients on weekly dosing consider holding GLP-1 agonists a week prior to the procedure/surgery.

Now, the American Gastroenterological Association (AGA) has published a “Rapid Clinical Practice Update,”

note that evidence is insufficient to make strong recommendations about continuing or withholding GLP-1 agonists prior to endoscopy. The AGA suggests an individualized approach: GLP-1 agonists “could be withheld” in patients who take the drugs solely for obesity, but the authors worry that omitting a dose in a patient with diabetes might confer more risk than benefit.

They say the scope should go on as long as the pt has been on an 8 hour solid fast and a 2 hour liquid fast



https://www.sciencedirect.com/science/article/pii/S1542356523008698?via%3Dihub