Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice. Read the related Insight. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: r. nial bradshaw/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Christa Lesté-Lasserre Learn more about your ad choices. Visit megaphone.fm/adchoices

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Fighting deepfakes, and using bacteria to deliver medicine inside the body

Fighting deepfakes, and using bacteria to deliver medicine inside the body

First up on the podcast, Meagan Cantwell produced a segment with Contributing Correspondent Kai Kupferschmidt on the fight against deepfakes. Kupferschmidt talks with Hany Farid, professor at the Univ...

14 Touko 31min

A team effort to save a giant fish, the power of moonlight, and how scientists can navigate a tough political environment

A team effort to save a giant fish, the power of moonlight, and how scientists can navigate a tough political environment

First up on the podcast, along Brazil’s Juruá River, local residents have been working with scientists to manage a giant fish called the arapaima—affecting the land, the people, and the economy. Contr...

7 Touko 53min

Watching a spiders’ heart beat, epigenetic ethics, and what science biographies reveal about fame

Watching a spiders’ heart beat, epigenetic ethics, and what science biographies reveal about fame

First up on the podcast, Online News Editor David Grimm shares a batch of fun stories with podcast host Sarah Crespi—from spider hearts racing when traffic gets loud to a disease-preventing house. Sta...

30 Huhti 46min

Cleaning up uranium mining, and how the heart avoids cancer

Cleaning up uranium mining, and how the heart avoids cancer

First up on the podcast, freelance science and environmental journalist Quentin Septer joins host Sarah Crespi to talk about a controversial uranium mine getting fast-tracked in South Dakota. Septer c...

23 Huhti 30min

The normals | Episode 3

The normals | Episode 3

The final of a three-part limited Science Podcast series that looks at the history of normal human subjects in research In episode two, we heard what happened to the normals program after church volu...

21 Huhti 33min

How to keep quantum computers cool, whether prediction markets harm public health, and podcasting on podcasting

How to keep quantum computers cool, whether prediction markets harm public health, and podcasting on podcasting

First up on the podcast, quantum computers require extremely low temperatures—less than 1°C away from absolute zero. But getting down to those temperatures has usually required dilution fridges using ...

16 Huhti 50min

The Normals | Episode 2

The Normals | Episode 2

Last time on The Normals, we learned that in the 1950s, the National Institutes of Health (NIH) wanted to recruit many healthy volunteers for basic research. Two peace churches, the Mennonites and the...

14 Huhti 27min

A chimpanzee ‘civil war,’ and NASA plans for nuclear propulsion

A chimpanzee ‘civil war,’ and NASA plans for nuclear propulsion

First up on the podcast, freelance science journalist Hannah Richter joins host Sarah Crespi to discuss NASA’s plans to send a nuclear-powered spacecraft to Mars in less than 3 years. Having not launc...

9 Huhti 42min

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