Turning anemones into coral, and the future of psychiatric drugs

Turning anemones into coral, and the future of psychiatric drugs

Why scientists are trying to make anemones act like corals, and why it’s so hard to make pharmaceuticals for brain diseases First up on this week’s show, coaxing anemones to make rocks. Newsletter Editor Christie Wilcox joins host Sarah Crespi to discuss the difficulties of raising coral in the lab and a research group that’s instead trying to pin down the process of biomineralization by inserting coral genes into easy-to-maintain anemones. Next on the show, a look at why therapeutics for both neurodegenerative disease and psychiatric illness are lagging behind other kinds of medicines. Steve Hyman, director of the Stanley Center for Psychiatric Research at the Broad Institute, talks with Sarah about some of the stumbling blocks to developing drugs for the brain—including a lack of diverse genome sequences—and what researchers are doing to get things back on track. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, associate editor Jackie Oberst discusses with Thomas Fuchs, dean of artificial intelligence (AI) and human health and professor of computational pathology and computer science at the Icahn School of Medicine at Mount Sinai, the potential and evolving role of AI in health care. This segment is sponsored by the Icahn School of Medicine at Mount Sinai. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Christie Wilcox; Sarah Crespi Episode page: https://www.science.org/doi/10.1126/science.adm6756 Learn more about your ad choices. Visit megaphone.fm/adchoices

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Keeping transgenic corn sustainable, and sending shrunken heads home

Keeping transgenic corn sustainable, and sending shrunken heads home

First up this week, Kata Karáth, a freelance journalist based in Ecuador, talks with host Sarah Crespi about an effort to identify traditionally prepared shrunken heads in museums and collections arou...

27 Helmi 202535min

Shrinking AI for use in farms and clinics, ethical dilemmas for USAID researchers, and how to evolve evolvability

Shrinking AI for use in farms and clinics, ethical dilemmas for USAID researchers, and how to evolve evolvability

First up this week, researchers face impossible decisions as U.S. aid freeze halts clinical trials. Deputy News Editor Martin Enserink joins host Sarah Crespi to talk about how organizers of U.S. Agen...

20 Helmi 202542min

Training AI to read animal facial expressions, NIH funding takes a big hit, and why we shouldn’t put cameras in robot pants

Training AI to read animal facial expressions, NIH funding takes a big hit, and why we shouldn’t put cameras in robot pants

First up this week, International News Editor David Malakoff joins the podcast to discuss the big change in NIH’s funding policy for overhead or indirect costs, the outrage from the biomedical communi...

13 Helmi 202539min

How the mantis shrimp builds its powerful club, and mysteries of middle Earth

How the mantis shrimp builds its powerful club, and mysteries of middle Earth

First up this week, Staff Writer Paul Voosen joins host Sarah Crespi to discuss mapping clogs and flows in Earth’s middle layer—the mantle. They also talk about recent policy stories on NASA’s reactio...

6 Helmi 202526min

Why it pays to scratch that itch, and science at the start of the second Trump administration

Why it pays to scratch that itch, and science at the start of the second Trump administration

First up this week, we catch up with the editor of ScienceInsider, Jocelyn Kaiser. She talks about changes at the major science agencies that came about with the transition to President Donald Trump’s...

30 Tammi 202526min

Unlocking green hydrogen, and oxygen deprivation as medicine

Unlocking green hydrogen, and oxygen deprivation as medicine

First up this week, although long touted as a green fuel, the traditional approach to hydrogen production is not very sustainable. Staff writer Robert F. Service joins producer Meagan Cantwell to disc...

23 Tammi 202533min

Rising infections from a dusty devil, and nailing down when our ancestors became meat eaters

Rising infections from a dusty devil, and nailing down when our ancestors became meat eaters

First up this week, growing numbers of Valley fever cases, also known as coccidioidomycosis, has researchers looking into the disease-causing fungus. They’re exploring its links to everything from dro...

16 Tammi 202533min

Bats surf storm fronts, and public perception of preprints

Bats surf storm fronts, and public perception of preprints

First up this week, as preprint publications ramped up during the beginning of the COVID-19 pandemic, so did media attention for these pre–peer-review results. But what do the readers of news reports ...

9 Tammi 202532min

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