The Curbsiders Internal Medicine Podcast24 Helmi 2025

#472 DIGEST: cfDNA & cancer in Pregnancy, Vitamin K2 for Leg Cramps, PRN anti-hypertensives, GLP-1 Agonists for AUD, Short-Course Antibiotics

Join us as we review recent articles and news featured in The DIGEST issues #59-61, including cfDNA and incidental detection of cancer in pregnancy, vitamin K2 for nocturnal leg cramps, the danger of as-needed anti-hypertensive medications in the hospital, GLP-1 agonists for alcohol use disorder, short-course (7 vs 14 days) antibiotics for bacteremia, and patient-collected HPV testing for cervical cancer screening. Fill your brain hole with a fully digestible meal! Featuring Laura Glick MD, Nora Taranto (@norataranto), Paul Williams (@paulnwilliamz), and Matt Watto (@doctorwatto).

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Show Segments

00:00 Introduction and Overview
02:57 The IDENTIFY study: Non-Invasive Prenatal Testing and Cancer Detection with cfDNA
05:54 Implications of Non-Reportable Results in Prenatal Testing
08:51 Vitamin K2: A New Approach to Managing Nocturnal Leg Cramps
12:07 Practicality and Future of Vitamin K2 in Clinical Practice
23:21 The Dangers of As-Needed Antihypertensives in the hospital
32:21 Exploring GLP-1 Agonists for Alcohol Use Disorder
40:24 Shorter Antibiotic Courses in Sepsis
46:09 Advancements in Patient-Collected HPV Screening for cervical cancer

Credits

Written and Produced by: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP
Show Notes: Nora Taranto MD
Cover Art: Matthew Watto MD, FACP
Hosts: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste

Disclosures

The Curbsiders report no relevant financial disclosures.

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