Hacking Oxytocin, How to Use Rapamycin, Level Up Your At-Home Cold Plunge, Curing Asperger’s & More! AMA #1 with Dave Asprey  : 1255

Hacking Oxytocin, How to Use Rapamycin, Level Up Your At-Home Cold Plunge, Curing Asperger’s & More! AMA #1 with Dave Asprey : 1255

In this first-ever AMA episode, Dave tackles your biggest biohacking questions—straight from The Upgrade Collective! From optimizing brain power to pushing the limits of cold therapy, this episode is packed with cutting-edge hacks to supercharge your body and mind. If you’d like to have your questions answered on the next AMA, click the link below for details on The Upgrade Collective membership, and get all sorts of extra biohacking add-ons for your life!

In today’s episode: What if you could amplify oxytocin—the “love hormone”—to build stronger relationships and lower stress? Or upgrade your cold plunge routine for max benefits in less time? Dave reveals the science behind these powerful biohacks, plus his take on rapamycin for longevity, the right way to supplement for thyroid health (without a prescription), and even how he personally overcame Asperger’s traits through neuroplasticity and mitochondrial upgrades. There’s even some great advice for all the parents out there!


What You’ll Learn:

• How to naturally boost oxytocin for better relationships and emotional health

• The fastest way to upgrade your cold plunge for heat shock benefits

• Is rapamycin really a longevity miracle? Dave’s personal take

• How mitochondria impact brain power, mood, and aging—and how to fix them today!

• The shocking reason some people can’t process reality correctly (and how to retrain your brain)

• The real truth about stem cells, exosomes, and V-cells for regeneration

• The hidden dangers of selenium, thyroid supplements, and over-fasting


SPONSORS

-Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.

-Calroy | Head to https://calroy.com/dave for an exclusive discount.

Resources:

Upgrade Collective Membership: https://www.ourupgradecollective.com

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Intro

00:37 – Welcome to the Human Upgrade AMA

01:13 – Cold Plunges and Alpha Lipoic Acid for Health

03:11 – Hot and Cold Therapy for Optimal Health

07:29 – Understanding Thyroid Health and Treatment

09:09 – The Importance of Selenium

14:41 – Stem Cells vs. Exosomes

16:27 – Rapamycin for Longevity

18:07 – Asperger’s Syndrome and Neuroinflammation

28:53 – Understanding Asperger’s and Self-Awareness

29:24 – The Challenge of Offering Help

30:06 – The Importance of Reconnection Work

31:34 – Personal Development Journey

34:42 – The Role of Emotions in Biohacking

35:55 – Dealing with Flashbacks and Trauma

45:46 – The Power of Oxytocin

49:48 – The Truth About Kale and Oxalates

54:25 – Teaching Kids to Regulate Their Nervous System

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1436)

#5: How To Quantify Fatigue Like Never Before

#5: How To Quantify Fatigue Like Never Before

Rick Green and John Kalns have created the first test that can objectively measure fatigue.  Using an at-home test for salivary peptides, you can now gauge exactly how much stress your body is under.  This test can be used by athletes, or businessmen and entrepreneurs who burn the candle at both ends.  This is the first test which allows you to know when you’re really pushing your self too far. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Syys 201139min

#4: Evolutionary Psychiatry With Emily Deans (Paleo Brain Hacking)

#4: Evolutionary Psychiatry With Emily Deans (Paleo Brain Hacking)

Emily Deans is a board certified adult psychiatrist who uses evolutionary clues to solve modern mental illnesses.  She runs a popular blog called Evolutionary Psychiatry, and another blog on psychology today.  Emily is considered one of the top experts on the connection between nutrition and mental performance.  She is well respected in the “paleosphere”, and was kind enough to share her knowledge on Upgraded Self Radio. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Syys 20111h

#3: Hacking Fatigue With Tim Noakes (Plus More 4 Hour Body Fun)

#3: Hacking Fatigue With Tim Noakes (Plus More 4 Hour Body Fun)

Dr. Tim Noakes is one of the world’s foremost exercise scientists and the author of numerous books including the Lore of Running.  From the University of Cape Town exercise research center, Dr. Noakes has worked with some of the greatest athletes of all time.  His research is redefining the way we think about fatigue in sports and regular life.  A lifelong runner (71 marathons and ultra-marathons), writer, and researcher (and more recently, a paleo eater), Tim Noakes has used his knowledge to hack the human mind for improved athletic performance.  Whether you’re an athlete or a cubicle dweller, you need to here this interview. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Syys 20111h

#2: The Dark Side of Fat Loss With Sean Croxton

#2: The Dark Side of Fat Loss With Sean Croxton

29 Elo 201153min

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