Dose Optimisation in the ICU: The Role of TDM and Model-Based Solutions
ESICM Talk5 Maalis 2025

Dose Optimisation in the ICU: The Role of TDM and Model-Based Solutions

Jaksot(90)

ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation

ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation

VA-ECMO outcome scores have been previously developed and used extensively for risk adjustment, patient prognostication, and quality control across time and centres. The limitation of such scores is t...

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Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting

Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting

Numerous Population Pharmacokinetic (PopPK) models have been developed for Piperacillin (PIP), most of which are based on small monocentric studies and may not be generalizable to other populations. A...

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Green ICU - Environmental Sustainability in intensive care

Green ICU - Environmental Sustainability in intensive care

The concept of a "green ICU" is increasingly important in today's world, as sustainability and environmental considerations become integral to healthcare practices. Hospitals, including ICUs, can have...

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Diving into ARDS with Prof. Gattinoni. From the new guidelines to bedside applied physiology.

Diving into ARDS with Prof. Gattinoni. From the new guidelines to bedside applied physiology.

Acute respiratory distress syndrome (ARDS) is the term applied to a spectrum of conditions with different etiologies that share common clinical-pathological characteristics including: increased perme...

20 Joulu 202339min

Sepsis-associated acute kidney injury in the intensive care unit. A multicenter observational study

Sepsis-associated acute kidney injury in the intensive care unit. A multicenter observational study

Sepsis‐associated acute kidney injury (SA‐AKI) is a common, increasingly prevalent problem in the intensive care unit (ICU). The association between sepsis and AKI has been studied previously. However...

8 Marras 202315min

Patient Transportation in Critical Care: introduction to our ACE course

Patient Transportation in Critical Care: introduction to our ACE course

Transportation of critically ill patients is inevitable in most health systems. Prehospital transportation (PHT) may be necessary after a major injury or as a result of a life-threatening illness – fo...

4 Loka 202312min

Interprofessional teamwork in ICU

Interprofessional teamwork in ICU

Intensive care units (ICU) are the most peculiar units in hospitals where the quality and safety of health care delivery should be at the highest level. The most critical patients are treated in this ...

27 Syys 202324min

Artesunate treatment in severely injured patients with traumatic haemorrhage

Artesunate treatment in severely injured patients with traumatic haemorrhage

Multiple organ dysfunction syndrome (MODS) is common after major trauma, affecting up to two-thirds of patients with critical injuries. Post-trauma MODS is associated with a mortality of over 20% and ...

20 Syys 202318min

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