This Is Your Brain on 2025: The Biohacker’s Guide to Mental Clarity & Mood | Dr. Drew Ramsey  : 1263

This Is Your Brain on 2025: The Biohacker’s Guide to Mental Clarity & Mood | Dr. Drew Ramsey : 1263

You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself?

In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain.

You’ll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain.


What You’ll Discover in This Episode:

• Why brain fog, anxiety, and mood swings might be signs your brain is inflamed

• How movement—especially dancing—can literally help your brain grow stronger

• What your gut has to do with your mental health (and why some “healthy” foods can backfire)

• The truth about antidepressants, supplements, and why there’s no one-size-fits-all fix

• Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive

• A new way to think about mental fitness—like a workout plan for your brain


SPONSORS

-BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.


Resources:

A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Drew’s Instagram: https://www.instagram.com/drewramseymd/?hl=en

Drew’s Linktree: https://shorturl.at/CIIR5

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

• 00:00 – Trailer

• 01:43 – Intro

• 02:51 – The State of Mental Health Today

• 04:00 – Nutritional Psychiatry and Personal Experiences

• 05:21 – Environmental Factors and Brain Health

• 05:55 – Chemical Balance and Psychiatry

• 09:19 – Mental Fitness and Connection

• 14:17 – Modern Brain Challenges

• 16:26 – The Role of Movement and Dance

• 22:44 – Sex, Relationships, and Mental Health

• 34:02 – Microbiome and Mental Health

• 36:50 – Transitioning to Urban Life and Mental Health

• 37:29 – The Role of Nature in Mental Well-being

• 38:14 – Personal Experiences with Gut Health

• 39:45 – Trial and Error in Mental Health

• 42:16 – Cognitive Resilience and High Performance

• 45:37 – The Importance of Family Meals

• 46:33 – Challenges of Rural and Urban Living

• 47:53 – Brain Health: Beyond Neurons

• 49:01 – Neuroplasticity and Mental Fitness

• 52:50 – Biohacking Mental Health

• 57:31 – The Role of Serotonin in Depression

• 01:03:57 – Debating the Benefits of Kale

• 01:12:03 – Final Thoughts on Mental Health and Resilience

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1436)

#5: How To Quantify Fatigue Like Never Before

#5: How To Quantify Fatigue Like Never Before

Rick Green and John Kalns have created the first test that can objectively measure fatigue.  Using an at-home test for salivary peptides, you can now gauge exactly how much stress your body is under.  This test can be used by athletes, or businessmen and entrepreneurs who burn the candle at both ends.  This is the first test which allows you to know when you’re really pushing your self too far. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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#4: Evolutionary Psychiatry With Emily Deans (Paleo Brain Hacking)

#4: Evolutionary Psychiatry With Emily Deans (Paleo Brain Hacking)

Emily Deans is a board certified adult psychiatrist who uses evolutionary clues to solve modern mental illnesses.  She runs a popular blog called Evolutionary Psychiatry, and another blog on psychology today.  Emily is considered one of the top experts on the connection between nutrition and mental performance.  She is well respected in the “paleosphere”, and was kind enough to share her knowledge on Upgraded Self Radio. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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#3: Hacking Fatigue With Tim Noakes (Plus More 4 Hour Body Fun)

#3: Hacking Fatigue With Tim Noakes (Plus More 4 Hour Body Fun)

Dr. Tim Noakes is one of the world’s foremost exercise scientists and the author of numerous books including the Lore of Running.  From the University of Cape Town exercise research center, Dr. Noakes has worked with some of the greatest athletes of all time.  His research is redefining the way we think about fatigue in sports and regular life.  A lifelong runner (71 marathons and ultra-marathons), writer, and researcher (and more recently, a paleo eater), Tim Noakes has used his knowledge to hack the human mind for improved athletic performance.  Whether you’re an athlete or a cubicle dweller, you need to here this interview. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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#2: The Dark Side of Fat Loss With Sean Croxton

#2: The Dark Side of Fat Loss With Sean Croxton

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