Nature Podcast26 Maalis 2025

New lasso-shaped antibiotic kills drug-resistant bacteria

In this episode:

00:46 Newly discovered molecule shows potent antibiotic activity

Researchers have identified a new molecule with antibiotic activity against a range of disease-causing bacteria, including those resistant to existing drugs. The new molecule — isolated from soil samples taken from a laboratory technician’s garden — is called lariocidin due to its lasso-shaped structure. The team say that in addition to its potent antibiotic activity, the molecule also shows low toxicity towards human cells, making it a promising molecule in the fight against drug-resistant infections.

Research Article: Jangra et al.

09:36 Research Highlights

A reduction in ships' sulfur emissions linked to a steep drop in thunderclouds, and the epic sea-voyage that let iguanas reach Fiji.

Research Highlight: Ship-pollution cuts have an electrifying effect: less lightning at sea

Research Highlight: Iguanas reached Fiji by floating 8,000 kilometres across the sea

13:54 Assessing the nuances of humans’ biodiversity impacts

A huge study analysing data from thousands of research articles has shown that the human impacts on biodiversity are large but are in some cases context dependent. The new study reveals that at larger scales, communities of living things are becoming more similar due to human influence, but at the smaller scale they are becoming more different. "These are generally unwanted effects on biodiversity," says study author Florian Altermatt, "this is one more very strong argument that stopping and reducing these pressures to halt and reverse biodiversity declines is needed."

Research article: Keck et al.

21:45 Briefing Chat

How a proposed green-energy facility in Chile could increase light pollution at one of the world’s most powerful telescopes, and how a calving Antarctic iceberg revealed an unseen aquatic ecosystem.

Nature: Light pollution threatens fleet of world-class telescopes in Atacama Desert

Scientific American: Stunning Antarctic Sea Creatures Discovered after Iceberg Breaks Away

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Briefing Chat: How 1,000 pairs of buried underpants helped measure soil health

In this episode:00:21 Our picks of this year’s Ig Nobel prizesNature: Buried underpants and a new definition of kissing win 2026 Ig Nobel prizes07:47 Massive xenon experiment detects tantalizing hint ...

4 Syys 12min

Audio long read: Could mending damaged DNA prolong life?

Scientists are amassing evidence that unrepaired or poorly repaired DNA damage underlies many of the hallmarks of ageing. This has led to research into whether boosting DNA repair can keep people heal...

2 Syys 18min

Briefing Chat: How Dolly Parton left her mark on science

In this episode:00:18 Researchers celebrate Dolly Parton's contributions to scienceNature: Dolly Parton dies aged 80 — researchers celebrate her contributions to science08:40 Phase III trial of melano...

28 Elo 14min

Highest-ever ocean temperatures recorded as El Niño intensifies

Why extreme temperatures are expected to weaken ocean carbon sinks — plus, how mitochondrial injections could treat vision loss.00:46 The world’s oceans reach a record temperatureNature: Ocean tempera...

26 Elo 19min

Briefing Chat: New narcolepsy drug could unlock host of novel brain therapies

Nature staff discuss how an FDA-approved drug for narcolepsy could have promise beyond the condition, and the longest-lived human brain organoids yet.00:28 The promise of a new narcolepsy drugNature: ...

21 Elo 12min

A black hole's spin could finally be measured by a high-speed star

Star orbiting close to Sagittarius A* could reveal its spin — plus, how exoskeletons might change the way humans move.00:46 The star that could reveal a black hole’s spinResearch article: Dayem et al....

19 Elo 29min

Briefing Chat: Anthropic rolls out new AI watermark — will it make a difference?

In this episode:00:29 What does Anthropic’s new watermark mean for research?Nature: Can Anthropic’s invisible watermarks curb ‘AI slop’? Researchers remain sceptical10:57 Ticklishness is a distinct, s...

14 Elo 16min

The probiotic bacteria engineered to treat diabetes

Genetically modified bacteria lower high blood-sugar in animal trials — plus, how to safely watch a solar eclipse.00:45 A living diabetes treatmentResearch article: Guan et al.08:03 Research Highlight...

12 Elo 19min