#322: Vitamin C: Your Secret Weapon Against Disease and Aging with Dr. Tom Levy

#322: Vitamin C: Your Secret Weapon Against Disease and Aging with Dr. Tom Levy

What if I told you that one of the biggest secrets to staying young, fighting disease, and even keeping your heart and arteries in top shape isn’t just about hitting the gym or eating clean?

Products mentioned in this episode:

Lypo-Spheric® Vitamin C

Sodium Ascorbate Powder

What we discuss:

The Role of Oxidative Stress and Vitamin C ... 00:03

Introduction of Dr. Thomas Levy and His Journey ... 00:07

Oxidative Stress and Its Impact on Health ... 00:08

Exercise, Hormones, and Antioxidants ... 00:19

Critical Importance of Oral Health ... 00:30

Heavy Metals and Heart Health ... 00:45

Chelation and Detoxification Methods ... 00:47

Long COVID, Spike Protein, and Vitamin C Protocol ... 00:52

Discussion on Vitamin C Sources and Supplementation ... 01:00

Conclusion and Contact Information for Dr. Levy ... 01:06

Our Amazing Sponsors:

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Jaksot(366)

END MYOPIA – Restore your eyesight so you can THROW your glasses away

END MYOPIA – Restore your eyesight so you can THROW your glasses away

In this episode Nathalie talks to Jake Steiner about reversing myopia…that’s right, actually regaining the ability to see from afar without needing glasses!! Jake stresses that he is not a medical doctor or optometrist he is simply a guy who set out to solve a problem for himself and in the process discovered some very “eye-opening” information (pun absolutely intended).   He established Endmyopia.org as a resource to offer myopes the opportunity to explore science, vision biology, and optics that affect their eyesight.  Jake advocates for an evidence-based approach to understanding myopia and methods to potentially reverse it.   Meet This Week's Guest Jake Steiner began a journey to reverse his -5.00 diopter myopia 20 years ago. It took a great deal of experimenting and trial and error to apply theoretical concepts found in clinical journals and peer reviewed studies, though he eventually managed to get back his natural 20/20 eyesight. Over the years he cataloged the many tools, resources, and experiences that made his myopia recovery a reality and is now committed to sharing this life changing information with as many people as he can possibly reach.   Key Takeaways: [01:20] Jake opens up about what lead him to his interest in eyes [01:38] Lens induced myopia [17:06] Jakes research journey [20:06] Fixing your eyesight [26:13] Measuring myopia at home [40:24] Overall health and lab work for eyes [43:56] The effect blue light and screens have on the eyes [51:21] Methods of learning more about improving eyesight  [61:12] Challenging and questioning the education system   Linkage: Endmyopia.org  YouTube: Click Here Facebook: Endmyopia   Episode Sponsor: -drinkHRW: For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts ....I have every one of my clients using drinkHRW tablets and they all love them too! Check out their amazing products at drinkHRW.com/ and use promo code Longevity10 to get 10% off your purchase!     - Disclaimer: This podcast is intended for educational purposes only and is not in any way intended to provide medical advice.  Please consult with your medical practitioner or health provider before making any changes to your diet, starting any new supplements or protocols.

3 Touko 20211h 15min

Master Your Hormones for Vitality & Longevity with 3 Leaders Dr. Erika Schwartz,  Dr. Suzanne Turner and Dr. Elizabeth Yurth

Master Your Hormones for Vitality & Longevity with 3 Leaders Dr. Erika Schwartz, Dr. Suzanne Turner and Dr. Elizabeth Yurth

In this week’s episode, three powerhouses in regenerative and functional medicine: Dr. Elizabeth Yurth, Dr. Erika Schwartz, and Dr. Suzanne Turner,  join me for a jam pack session of insights on women’s hormones. We take on the topic of managing hormones as they move into and through menopause. Doing so can protect your health, your vitality, your longevity, your mood as well as how you look and feel. We talk about bio-identical hormone replacement therapy and bust some of the harmful myths that have been perpetuated about it. Whether you are a woman going through this important transition yourself or, have someone in your life who is, you owe it to yourself and the people around you to get educated about this. Meet this week’s guests:   All three of this week’s guests are Fellows of Dr. Seeds SSRP Mastermind.   Dr. Elizabeth Yurth MD is the Co-Founder and Medical Director of Boulder Longevity Institute.  Along with her 25-plus years as a practicing orthopedist specializing in sports, spine, and regenerative medicine, Dr. Yurth is double-Board Certified in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine.   She is also part of the first cohort of providers to receive the A4M National Peptide Certification.   Dr. Erika Schwartz MD is the founder of ES Health takes the best of conventional and integrative medicine and applies them to preventing disease.  She was one of the first doctors in the US to treat patients with bio-identical hormones, conduct biomarker testing, and to administer preventative IVs. Dr. Erika has authored six best selling books for the public along with medical articles and numerous blogs, YouTube channel and bylined articles in the highest circulation publications of the world.    Dr. Suzanne Turner MD is the founder of Vine Medical Associates. She is double Board Certified in Family Medicine and AntiAging and Regenerative Medicine.  Practicing Functional Medicine, Dr. Turner is an industry expert and speaker on bioidentical hormone therapy, metabolic medicine, neurodegenerative disease, and human performance optimization. She has earned Advanced Certification in Endocrinology and Peptide Therapy and is the leading expert in peptide therapy in the Southeast.   Key Highlights: [02:33] People need hormones not just for the youthful looking but also for greater health [06:18] Hormones produce better in sleep, which in turn will help to support healthy testosterone and progesterone levels  [09:57]  Differences of each hormones and their roles  [13:20] The benefits of Exercising after a meal  [15:36] The difference between synthetic and bioidentical hormones [23:33] The downsides of Birth control on hormones which can affect sexual satisfaction   [27:09] Three different pathways which are largely genetic based on some cytochrome pathways and a lot environmental as well [36:28] Athletic type persons have more estrogen than others [41:35] When is the best time to start hormone replacement therapy? [45:25]  Strategies in obtaining growth hormones and how it helps the cells to improve the energy production of every cell    Connect: Dr. Yurth’s website Dr. Schwartz’s website Dr. Turner’s website   Instagram:  Dr. Yurth’s: @dryurth Dr. Schwartz:  @drerika218 Dr Turner: @DrSturner   Disclaimer: This podcast is intended for educational purposes only and is not in any way intended to provide medical advice.  Please consult with your medical practitioner or health provider before making any changes to your diet, starting any new supplements or protocols.

26 Huhti 20211h

MyVitalC C60:  Improve Focus, Energy, Sleep and Vitality with Chris Burres

MyVitalC C60: Improve Focus, Energy, Sleep and Vitality with Chris Burres

In this episode, Chris Burres shares how he went from carbon nanomaterial engineer to supplement manufacturer when he and his partners launched MyVitalC - an offshoot of ESS60 that manufactures Carbon60 as a health & longevity supplement for humans and pets.  C60 first got health enthusiasts’ attention when toxicity trials were published that showed that C60 extended the lifespan of Wister Rats by a shocking 90 percent!  While there is still much to be learned about this amazing molecule all arrows point to it acting as a powerful anti-oxidant compound with myriad downstream health benefits.     Meet this week’s guest: Chris Burres is a research engineer and scientist whose primary mission is to help people live longer, healthier, pain-free lives. Burres has a diverse background in the field of inventions and manufacturing. With a BS in Mechanical Engineering from University of Houston, Burres is a co-inventor of patents related to the use of explosives in downhole oil well drilling, a co-inventor of the most efficient fullerene manufacturing equipment in use since 1991, and co-owner of a company that manufactures a unique product containing a Nobel-Prize winning molecule that has been shown to extend the lifespan of test subjects by 90 percent. To try MyVitalC for yourself go to MyVitalC.com/BSPNN  and use Promo code BSPNN to save $15 off your first purchase.   Key Highlights: [03:53] What is Carbon Nanomaterial and what’s it got to do with ESS60?   [7:28] Toxicity studies shockingly showed that consumption of C60 which was expected to be toxic actually resulted in a 90% increase in lifespan in Wister rats 9:07 The leap from industrial material to longevity supplement - how that one study caused the birth of a new longevity supplement [10:06] C60 vs. ESS60. What is the difference?  C60 is specialized for industrial use while ESS60 is mainly for human consumption. [11:11] Research shown that Wister rats that are bred to develop tumours as they age were given ESS60 were able to live 90% longer without developing those tumours 14:55 The reports that started to come back from people experimenting with ESS60 [17:47] The detailed process and foundation of ESS60   20:04 How much actual ESS60 can you dissolve in Olive Oil? [21:24] What the color of your C60 product tells you about the oil that was used (MCT Oil + C60 is purple, Olive Oil + C60 is brownish).  The truth about the photosensitivity of C60 in Olive Oil - discussing the study that brings up concerns about what happens to C60 in Olive Oil when exposed to light. [26:04 ] The wonders of ESS60 as based on the feedback of customers and users.  [28:04] Feedbacks from the customer were reporting various benefits. When the C60 taken by the morning, users report improved focus during the day and better sleep at night. [30:52] Beware the placebo effect - no matter what the supplement! [41:30] Olive oil  has great antioxidant and anti-inflammatory properties which may contribute to the  benefits people are reporting [46:00] Difference of ESS60 in MCT Oil [48:15] Awareness of false advertising in the market and choosing supplements [55:03] ESS60’s ability as antioxidant capacity and its limitations [01:17] Why is olive oil the best carrier oil for ESS60   Linkage:  MyVitalC.com Promo Code: BSPNN to save $15 off your first order.   Connect : Twitter

19 Huhti 20211h 31min

Integrative Peptides with Dr Kent Holtorf :Bringing Oral Peptides to the Market

Integrative Peptides with Dr Kent Holtorf :Bringing Oral Peptides to the Market

In this episode, Dr Kent Holtorf and I talk about how he first found peptides and how they have transformed his health and the way he practices medicine.  We then discuss the oral peptides available through Integrative peptides TB4Frag for repair and immune support, BPC 157 for repair, KPV for inflammation and CerebroPep for the brain  and what’s coming next….   Meet this week’s guest: Kent Holtorf, M.D. is the medical director of the Holtorf Medical Group and a founder and director of the non-profit National Academy of Hypothyroidism (NAH), which is dedicated to the dissemination of new evidence-based information to doctors and patients on the diagnosis and treatment of hypothyroidism and advanced integrative diagnostic and treatment protocols. He has personally trained numerous physicians across the country in the use of bioidentical hormones, hypothyroidism, peptide therapy, stem cell therapy, complex endocrine dysfunction and innovative treatments of chronic fatigue syndrome, weight loss, fibromyalgia, and chronic infectious diseases, including Lyme and related diseases. Lyme and associated diseases have been the focus of the Holtorf Medical Group centers and have been a passion of Dr. Holtorf’s for over 15 years. To try these for yourself: IntegrativePeptides.com use Promo Code Longevity10 to get 10% off   Key Takeaways:  2:12 How Dr Holtorf found Integrative Medicine 4:30 His health journey through med school that led to starting National Academy of Hypothyroidism, a nonprofit thyroid association 6:42 How discovering hangover free beer led to the founding of a Beer Company 8:47 Opening up 2 centers, his stressful divorce, experiencing the difficult times 9:50 Then Dr Holtorf found peptides …. Everything changed from there 12:01 In very ill patients peptides can revive the immune system so that fewer antibiotics can get the job done 15:28 When you look at the way the body works, we think of signaling it's kind of like hormones 16:17 BPC puts the body back in homeostasis 17:25 How the thymus peptides restore balance in the immune system 24:38 The link between Autoimmune conditions and infections 26:30 They do initial panel, they can pick out who has these multisystem illness and how bad it is 28:42 Thymosin alpha 1  36:00  KPV - orally bioavailable suppresses mast cells, busts biofilms, anti candida… 39:00 How can BPC be so big a molecule and still be orally bioavailable? The rule of 5.. 42:47 BPC 157 may protect EMF’S through stabilization of cellular calcium channels 48:34 TB4 supports autophagy by supporting mitochondria  50:00 TB4 and cancer - rushing to the rescue? 54:13 CerebroPep - Integrative Peptide’s oral version of Cerebrolysin 59:19 Coming soon: Peptigenic, an analgesic stem cell cream with peptides in it 1:07 Heavy Metals often don’t cause issues till there’s an infection involved Linkage: Dr. Richard Horowitz DNA ConneXions Peptigenic   Connect: www.NAHypothyroidism.org www.HoltorfMed.com www.integratedpeptides.com (Use code LONGEVITY10 to get 10% off your purchase)     Disclaimer: Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

12 Huhti 20211h 24min

Dr Mindy Pelz, DC, MENOPAUSE IS AN EXTREME SPORT - How targeted lifestyle changes can help women through this transition with ease and grace instead of suffering

Dr Mindy Pelz, DC, MENOPAUSE IS AN EXTREME SPORT - How targeted lifestyle changes can help women through this transition with ease and grace instead of suffering

In this episode Nathalie talks to Dr Mindy Pelz about her new book - The Menopause Reset - virtually a “user’s manual” on how women can reclaim power over their health by understanding and supporting their hormones.  The book is fantastic - it is short and to the point and explains in detail how each woman can make simple yet powerful changes to their diet and lifestyle that will support their cycles while helping them to look, feel and perform their best.   Meet this week’s guest: Dr. Mindy Pelz, D.C is a best selling author, keynote speaker, nutrition and functional medicine expert who has spent over two decades helping thousands of people successfully reclaim their health. She is a recognized leader in the alternative health field and a pioneer in the fasting movement, teaching the principles of a fasting lifestyle, diet variation, detox, hormones, and more. Her popular YouTube channel combines the latest science with practical lifestyle tools every person can use to reset their health. She is the host of one of the leading science podcasts, The Resetter Podcast, and the author of three best-selling books; The Menopause Reset, The Reset Factor, and The Reset Kitchen.   Dr Pelz’ transition from Chiropactor to Functional Medicine Practitioner was ultimately triggered 10 years into her career as she started to realize that people were unable to heal due to their environment.   Key Takeaways: 2:19 Hitting menopause ultimately drove Dr Pelz to start digging into what exactly is happening to women in this transition and, more importantly, that finding a solution was going to have to come from her...not her doctor, not a pill. 7:10 The external influences - like makeup, processed foods, anxiety that affect women’s hormonal cycles 7:46 The beauty of women’s hormones….and how staying in sync with these hormones can help us to make the most of them 8:21 How something as simple as seed cycling can help to support hormonal balance 10:35 What foods to eat at different times of your cycle to support your hormones so that you can look, feel and perform your best… 11:03 Day 1-Day 10 the perfect time to fast, go Keto or  push yourself a little harder. 11:41 Day 11-Day15 this is the time to BUILD muscle and support your microbiome..”bathe yourself in sauerkraut”  Day 15-20 it’s back to Keto, fasting etc…. 12:55 Day 20 is when you get to chill out...progesterone support is now the priority and healthy carbs are the name of the game… 13:36 How and why the Ketogenic Diet can backfire for many women 16:21 Helping women to take back their power over their health  19:49 There are two types of the energy system: sugar burner energy system and fat burner energy system 21:14 By doing sugar burner energy source should avoid preservative foods 34:19 Forty years old and above should eat more leafy foods for estrogen wealth 38:11 Doing HRT is best to complement a healthy lifestyle  45:32 Menopause has a different outlook on every other woman not like the standard perception  52:35 Oxytocin is an anabolic and major key in hormone growth 01:02:22 Dry fasting benefits will get us to deeper ketosis but should be under 24hrs fasting period only   Linkage: The Menopause Reset book Master Amino acid Pattern Jason’s Fung Book’s   Connect: Website: www.drmindypelz.com Dr Pelz YouTube channel       Disclaimer: Please note that this podcast is for information purposes only. None of the content is intended as medical advice – before undertaking any new health initiative be it a change in diet, lifestyle or supplementation please consult with your medical practitioner.

5 Huhti 20211h 15min

Dr Amy Killen Optimizing Sexual & Skin Health

Dr Amy Killen Optimizing Sexual & Skin Health

Dr Amy Killen, anti-aging and regenerative medicine physician specializes in beautifying skin and sexual rejuvenation.  In this episode we talk about how she made the unlikely transition from emergency medicine to the field she is in today and the many ways that she is able to now support her patients to better overall health through the lens of improving skin and sexual health.    She is Board Certified in Emergency Medicine with more than ten years of direct patient care, practicing Anti-Aging and Regenerative Medicine for more than five years and an advocate for empowering patients to look and feel their best by merging lifestyle modification, hormone optimization, personalized medicine and regenerative therapies.   Meet this week’s guest: Dr. Amy Killen MD is an anti-aging and regenerative physician specializing in sexual optimization and aesthetics. An international speaker, teacher, author and clinical practice owner, Dr. Killen is an outspoken advocate for empowering patients to look and feel their best by merging lifestyle modification, hormone optimization, personalized medicine, and regenerative therapies. Key Highlights: [06:19] Her discovery and interests in the field of regenerative medicine [07:24] What is PRP or Platelet-rich plasma? [10:20] Differences between stem cells and plasma [22:37] The ideal age to start taking peptides and other facial rejuvenation procedures [22:49] Different strategies to rejuvenate your face and skin [26:43] Peptides for Anti Aging and Rejuvenation [34:15] Alternative therapies for erectile dysfunction [39:57] Who is easier to treat a woman or man?  [46:22] The uses and classification of supplements [47:49] Shockwave Therapy works as does PRP which helps for erectile dysfunction    Linkage:  PRP  Shockwave Therapy   Connect :  Instagram Twitter Facebook Website Youtube

29 Maalis 20211h 7min

Osteoarthritis with Dr Elizabeth Yurth - Peptides, Treatments & Prevention

Osteoarthritis with Dr Elizabeth Yurth - Peptides, Treatments & Prevention

As Dr Yurth says:  Osteoarthritis is not a “you’ve run too many miles” problem - it is a disease process that may be avoided altogether if caught early enough and treated if addressed properly.  We explore the many ways that this debilitating condition can be addressed including some of the strategies that Dr Yurth uses in her clinic with her patients - we talk about peptides, addressing underlying causes and a few powerful supplements that can make a real difference.    Meet this week’s guest:  Dr. Elizabeth Yurth, MD is the Founder and clinical director of the Boulder Longevity Institute in Boulder Colorado. Her specialties include Orthopaedic Surgery, Physical Medicine & Rehabilitation, Sports Medicine, Longevity and Regenerative Medicine.  Dr. Yurth is Board Certified in Anti-Aging Medicine, has her advanced Fellowship Training in Anti-Aging Medicine, is a Member of the American Academy of Anti-Aging Medicine.  She is also a faculty member of the SSRP - Seeds Scientific Research and Performance Mastermind.   Key Highlights: [1:01] Why Dr. Yurth left the Orthopedic Practice she helped to Co-Found 27 Years ago [3:21] Why arthritis gets pushed to the background of chronic preventable diseases [5:44] Where senescent cells come into play in joint health [6:17] Where inflammation comes into play in the development of arthritis [7:21] A study on mice that may highlight the link between interleukin 1 Beta + the development of arthritis [9:00]Why steroids injected into an inflamed joint is a bad play for the long term [9:50] The loss of cytokines as part with the downward spiral into disability in advancing age [11:46] Why exercising remains a priority even when injured [12:46] Study on Rheumatoid Arthritis + movement vs. rest [13:10] the link between ACL reconstruction + arthritic knees and how EGCG may be able to help [14:35] Pentosan Polysulphate's place in post surgical recovery [15:30] How Pentosan Polysulphate works and on how it studies  [18:20] The difference between the oral version of PP(Elmoron) and the injectible [20:39] Where to get PP and why just using veterinary products on humans may not be a great idea [21:59] AOD9604+ Pentosan Polysulphate + Hyaluronic Acid [23:41] Pentosan Polysulphate after surgery [24:06] How to offset the High levels of certain inflammatory nucleays can reduce the efficiency of stem cell treatments [28:55] Dr. Yurth on Red Light Therapy [33:58] What Dr. Yurth does to block inflammation Pentosan, EGCG, Melatonin [34:22] High dose Melatonin as an anti-inflammatory [35:52] High Dose of Melatonin for Septic Babies [37:00] Epigallocatechin (EGCG) and Spermidine for the win! [37:52] EGCG Pre workout to increase muscle growth Myostatin Follistatin. EGCG under 4 grams/day may bump liver enzymes in some people. 1 gram/day maintenance increase in disease states [39:07] Spermidine + Osteoarthritis [41:25] Some helpful info for Post Covid Recovery [43:57] Addressing Acidic States - Alka Seltzer Gold   Linkage:  Cytokines ACL Injury Aod 9604 Human Optimization Academy   Connect with  Dr. Yurth: Boulder Longevity Institute Linkedin Instagram: @dryurth

23 Maalis 20211h

Amy Lamotte on the Anti aging Effects of Spermidine Part 2

Amy Lamotte on the Anti aging Effects of Spermidine Part 2

This episode is the second of a two-part series on Primeadine: a new healthy aging Spermidine supplement that is already getting rave reviews.  Spermidine is a potent polyamine, known for inducing autophagy or cellular renewal.  As we age, our bodies are getting slower and slower in the production of spermidine leaving us more reliant on exogenous sources be they food or supplementation.  Supplementation with spermidine in humans has been shown to support cognition and heart health, balance hormones and improve hair growth and fullness (including eyelashes),  strengthening nails.  Spermidine also positively impacts five of the nine hallmarks of aging including: misfolded proteins (impaired proteostasis), epigenetic changes, mitochondrial dysfunction, stem cell dysfunction, impaired cellular communication. Amy Lamotte is a fellow biohacker and in this episode, she shares her amazing hacks and simple and effective techniques that anyone can follow. We talk about the benefits of Spermidine, its mechanisms, and how it induces autophagy. She also shares about how she hacked her autoimmune disease, treating it and reversing it herself through diet, supplementation and testing. You shouldn’t miss this episode. Listen in!   Meet this week’s guest: Amy Lamotte is the Managing Director of Vallotte Nutrigenomics Limited in Hong Kong. She is a clinical nutritionist and researcher specializing in personalized nutrition, nutritional biochemistry, nutrigenetics, and nutrigenomics. Other areas of interest include anti-aging, circadian biology, and the microbiome. She has a Master’s of Science in Human Nutrition (summa cum laude) from the University of Bridgeport and a J.D. from Yale Law School. Key Highlights: [13:38] The mechanisms of Spermidine [06:05] What is autophagy and why is it important?   [19:41] The influence of Spermidine levels in different age groups  [22:12] Different factors and theories in dysregulation of spermidine [25:07] Diet has a big effect on preventive healthcare [26:50] The two great powerful combo - diet and supplements [31:35] What are the best supplements to take and not to take? [34:53] There are two types in human studies: epidemiological studies and clinical trials [38:44] The human clinical study of spermidine and the after results   Linkage:  Oxford Healthspan  (Use promo code BIONAT15 to save 15% off your order.)   Connect with Amy: Instagram: @amylamotte Linkedin: https://www.linkedin.com/in/amy-valley-lamotte-501676111/  Website: https://www.amylamotte.com/    Promo code:  Bionat15 for 15% off for your full order To Try Primeadine: Primeadine.com   REFERENCES FROM PODCAST INTERVIEW:  REVIEW ON DIETARY & GUT MICROBIOTA POLYAMINES  Ramos-Molina, B., Queipo-Ortuño, M. I., Lambertos, A., Tinahones, F. J., & Peñafiel, R. (2019).  Dietary and gut microbiota polyamines in obesity-and age-related diseases. Frontiers in  nutrition, 6, 24.  EPIDEMIOLOGICAL STUDIES RE SPERMIDINE/POLYAMINES  Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., ... & Madeo,  F. (2016). Cardioprotection and lifespan extension by the natural polyamine  spermidine. Nature medicine, 22(12), 1428-1438.  Kiechl, S., Pechlaner, R., Willeit, P., Notdurfter, M., Paulweber, B., Willeit, K., ... & Willeit, J.  (2018). Higher spermidine intake is linked to lower mortality: a prospective population-based  study. The American journal of clinical nutrition, 108(2), 371-380.  Pucciarelli, S., Moreschini, B., Micozzi, D., De Fronzo, G. S., Carpi, F. M., Polzonetti, V., ... &  Napolioni, V. (2012). Spermidine and spermine are enriched in whole blood of  nona/centenarians. Rejuvenation research, 15(6), 590-595  Schwarz, C., Horn, N., Benson, G., Calzado, I. W., Wurdack, K., Pechlaner, R., ... & Flöel, A.  (2020). Spermidine intake is associated with cortical thickness and hippocampal volume in  older adults. NeuroImage, 221, 117132.  Soda, K., Kano, Y., & Chiba, F. (2012). Food Polyamine and Cardiovascular Disease-An  Epidemiological Study. Global journal of health science, 4(6), 170.  HUMAN TRIALS RE SPERMIDINE  Pekar, T., Bruckner, K., Pauschenwein-Frantsich, S., Gschaider, A., Oppliger, M., Willesberger,  J., ... & Jarisch, R. (2020). The positive effect of spermidine in older adults suffering from  dementia. Wiener klinische Wochenschrift, 1-8.  Schwarz, C., Stekovic, S., Wirth, M., Benson, G., Royer, P., Sigrist, S. J., ... & Flöel, A. (2018).  Safety and tolerability of spermidine supplementation in mice and older adults with subjective  cognitive decline. Aging (Albany NY), 10(1), 19.  Wirth, M., Benson, G., Schwarz, C., Köbe, T., Grittner, U., Schmitz, D., ... & Flöel, A. (2018). The  effect of spermidine on memory performance in older adults at risk for dementia: A  randomized controlled trial. Cortex, 109, 181-188.  IN VIVO STUDY RE MICROBIAL SPERMIDINE PRODUCTION & BONE  Chevalier, C., Kieser, S., Çolakoğlu, M., Hadadi, N., Brun, J., Rigo, D., ... & Trajkovski, M.  (2020). Warmth prevents bone loss through the gut microbiota. Cell metabolism, 32(4), 575- 590.  POLYAMINES/SPERMIDINE IN FOOD  Handa, A. K., Fatima, T., & Mattoo, A. K. (2018). Polyamines: bio-molecules with diverse  functions in plant and human health and disease. Frontiers in chemistry, 6, 10. Kandasamy, S., Yoo, J., Yun, J., Kang, H. B., Seol, K. H., & Ham, J. S. (2021). Quantitative  Analysis of Biogenic Amines in Different Cheese Varieties Obtained from the Korean Domestic  and Retail Markets. Metabolites, 11(1), 31.  Okamoto, A., Sugi, E., Koizumi, Y., Yanagida, F., & Udaka, S. (1997). Polyamine content of  ordinary foodstuffs and various fermented foods. Bioscience, biotechnology, and  biochemistry, 61(9), 1582-1584.  SEX DIFFERENCES RE EXERCISE & AUTOPHAGY INDUCTION  Escobar, K. A., Welch, A. M., Wells, A., Fennel, Z., Nava, R., Li, Z., ... & Mermier, C. M. (2020).  Autophagy response to acute high-intensity interval training and moderate-intensity continuous  training is dissimilar in skeletal muscle and peripheral blood mononuclear cells and is  influenced by sex. Human Nutrition & Metabolism, 200118.

17 Maalis 20211h 6min

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