The Curbsiders Internal Medicine Podcast14 Huhti 2025

#479 Managing Treatment-Resistant Depression featuring Dr. Jessi Gold

Lead the way in depression management! We’re joined by Dr. Jessi Gold, a psychiatrist and mental health advocate, who provides essential pearls on ways to recognize the multifaceted nature of depression and similarly presenting medical conditions. We also discuss the complexities of treatment options including various medication options and therapies, and how to choose between these treatments.

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Show Segments

Intro
Case 1 from Kashlak
Medical conditions that can mimic depression
Diagnosis of depression
How to explain depression to family
Initial treatment options for depression
Case 2 from Kashlak
Suicide risk assessment
Trialing, augmenting, and tapering of medications
Pharmacogenetic testing
Alternate treatment options: TMS, ECT, ketamine, psilocybin, cannabis
Outro

Credits

Written and Produced by: Zoya Surani
Show Notes, Infographic, and Cover Art: Zoya Surani
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai Achi MD,MBA,FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Jessi Gold, MD

Disclosures

Dr. Gold reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.

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