Episode 398: How Breakthrough Discoveries in MS Research Will Impact MS Care with Dr. Amit Bar-Or
RealTalk MS14 Huhti 2025

Episode 398: How Breakthrough Discoveries in MS Research Will Impact MS Care with Dr. Amit Bar-Or

Last week, at the American Academy of Neurology annual meeting, Dr. Amit Bar-Or received the John Dystel Prize for Multiple Sclerosis Research for his multiple achievements that have advanced our knowledge of neuroimmunology, precision medicine, and biomarkers in MS. We talked with Dr. Bar-Or about how some of the latest discoveries in MS research would impact patient care.

Tolebrutinib, an investigational disease-modifying therapy, is currently making its way through the FDA's regulatory process. Last week, the results of the Phase 3 clinical trials for Tolebrutinib were published, and we're sharing the details.

We'll also tell you about MindGlide, an AI-powered tool for analyzing MRI scans that will significantly reduce MRI exam times.

We're talking about the results of the Phase 3 clinical trial for high-dose Ocrevus.

And we'll tell you about a cell therapy that doesn't use stem cells that successfully repaired myelin in the mouse model of MS -- twice!

We have a lot to talk about! Are you ready for RealTalk MS??!

Congratulations to Dr. Stephen Hauser and Dr. Alberto Ascherio :22

This Week: The impact of breakthrough MS research on MS care 2:17

Results of the phase 3 clinical trials for Tolebrutinib have been published 3:07

An AI-powered tool for analyzing MRI scans will significantly reduce MRI exam times for patients 4:21

Results of the phase 3 clinical trial for high-dose Ocrevus 8:13

A cell therapy that doesn't use stem cells has successfully repaired myelin in the mouse model of MS -- twice! 10:14

Dystel Prize winner Dr. Amit Bar-Or discusses how some of the latest discoveries in MS research will impact MS care 12:39

Share this episode 22:36

Have you downloaded the free RealTalk MS app? 22:56

SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/397

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!

LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist
Web: https://nationalmssociety.org/advocacy
Email: msactivist@nmss.org

RealTalk MS Episode 310: The Face Laughs While The Brain Cries: The Education of a Doctor with Dr. Stephen Hauser
https://realtalkms.com/310

RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh
https://realtalkms.com/ectrims244

VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh
https://youtu.be/zcBmAHRTotA

VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Nonrelapsing Secondary Progressive MS with Dr. Robert Fox
https://youtu.be/tJQ93qdlXrU

STUDY: Tolebrutinib Versus Teriflunomide in Relapsing Multiple Sclerosis
https://nejm.org/doi/full/10.1056/NEJMoa2415985

STUDY: Tolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis
https://nejm.org/doi/full/10.1056/NEJMoa2415988

Enabling New Insights from Old Scans By Repurposing Clinical MRI Archives for Multiple Sclerosis Research
https://www.nature.com/articles/s41467-025-58274-8

Fibroblast Technology
https://fibrobiologics.com/technology/#cnsms

Join the RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

Download the RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

Download the RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

Give RealTalk MS a rating and review
http://www.realtalkms.com/review

Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 398
Guests: Dr. Amit Bar-Or

Privacy Policy

Jaksot(502)

Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle

Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle

Last week, about 170 MS activists from across the country gathered in Washington, D.C. to participate in the National MS Society's Public Policy Conference. It's hard to come away from this event and ...

30 Maalis 31min

Episode 447: Walking with Many Sisters Toward a Cure with Brigitte Delaney

Episode 447: Walking with Many Sisters Toward a Cure with Brigitte Delaney

In 1988, there were just 42 Walk MS events, raising approximately $4 million. In 2025, there were 170 events across the country that raised over $30 million. As the largest private funder of MS resear...

23 Maalis 23min

Episode 446: MS Advocacy and the National MS Society's Public Policy Conference with Steffany Stern

Episode 446: MS Advocacy and the National MS Society's Public Policy Conference with Steffany Stern

175 MS activists are heading to Washington, D.C. next week for the National MS Society's Public Policy Conference. Their mission: to bring the concerns of the MS community directly to lawmakers on Cap...

16 Maalis 34min

Episode 445: It's MS Awareness Week with Kristine Werner Ozug and Kim, Kim, and Kim

Episode 445: It's MS Awareness Week with Kristine Werner Ozug and Kim, Kim, and Kim

It's MS Awareness Week, and this year we're diving into a theme that hits home for millions: Unseen MS. Multiple sclerosis is a master of disguise; it can be entirely invisible to the naked eye while ...

9 Maalis 40min

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

You know them by their trade names such as Ozempic, Wegovy, Mounjaro, and Zepbound. This class of medications is known as GLP-1 receptor agonists. And while they are best known for managing diabetes a...

2 Maalis 31min

Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith

Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith

Welcome back to the third and final part of our coverage of the 2026 ACTRIMS Forum. This week's episode bridges the gap between groundbreaking clinical research and the nuanced reality of living with ...

23 Helmi 35min

Episode 442: The 2026 ACTRIMS Forum (Part 2) with Dr. Jeffrey Cohen, Dr. Daniel Ontaneda, and Kristine Werner Ozug

Episode 442: The 2026 ACTRIMS Forum (Part 2) with Dr. Jeffrey Cohen, Dr. Daniel Ontaneda, and Kristine Werner Ozug

Welcome back to Part Two of our coverage of the 2026 ACTRIMS Forum. This week, we shift our focus to emerging therapies and clinical insights that are re-shaping the future of MS care. From the latest...

16 Helmi 44min

Episode 441: The 2026 ACTRIMS Forum with Dr. Manuel Friese, Dr. Amit Bar-Or, and Dr. Haritha Desu

Episode 441: The 2026 ACTRIMS Forum with Dr. Manuel Friese, Dr. Amit Bar-Or, and Dr. Haritha Desu

Last week, over 1,400 scientists and clinicians gathered in San Diego, California, at the 2026 Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the A...

9 Helmi 33min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
tiedenaiset-podcast
rss-pitaisko-erota
vakeva-elama-viisaampi-mieli-vahvempi-keho
rss-narsisti
meditaatiot-suomeksi
terapiassa
junnut-pelissa
puhu-muru
aamukahvilla
rss-kuumilla-aalloilla
paritellen
rss-uplevel-by-sonja-hannus
rss-nautinto
rss-pt-paahtio
rss-mighty-finland-podcast
paaasia-podcast
katilon-kahvitunti