Web3 & the Future of Genetics: AI, Blockchain & Data Ownership with Nillion  : 1271

Web3 & the Future of Genetics: AI, Blockchain & Data Ownership with Nillion : 1271

Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you.

But what if there was a way to take it back… and hack the system?

In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data.

Together, they break down the Web3 tech stack powering this revolution. Enter Nillion, a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away.

From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself.


What You’ll Learn in This Episode:

• Why your DNA is already in government databases—and how long they keep it

• How Nillion enables secure computation on private data

• What it means to build a “cybernetic operating system” for your body

• Why Fulcra.ai is building the orchestration layer of human optimization

• How Monadic DNA helps you profit from your genetics—without giving them away

• Why owning your data is the next frontier of biohacking

• The surprising connection between decentralization, health freedom, and consciousness

• How to join the movement toward true data sovereignty


If you’ve ever felt like you’re giving away too much to big tech, big pharma, or just the internet itself—this conversation will change how you see your data… and your body.


**Join the Fulca sleep study today! Visit https://fulcra.ai/sleep to sign up**

**Get a 30% discount on Fulca with code “DAVE”!


SPONSORS

-IGNITON | Go to https://www.biohackingconference.com/ and get your tickets while there are still great discounts available. Go to https://www.igniton.com/DAVE and use code DAVE to save 15%.

-Calroy | Head to https://calroy.com/dave for an exclusive discount.


Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Fulcra Dynamics Websitehttps://www.fulcradynamics.com/

MonadicDNA Website: https://monadicdna.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com

Timestamps:

00:00 – Trailer

02:01 – Intro

02:26 – Data Privacy & AI: The Big Shift

03:21 – Meet Michael Tiffany

04:41 – Cybernetic Operating Systems

05:13 – Wearables & Personal Augmentation

08:21 – Meet Vishakh: DNA Privacy Mission

09:25 – Why Genetic Data Needs Protection

11:30 – New Tech: Encryption & Privacy Tools

16:13 – How Multi-Party Compute Works

41:58 – Emergence: Behavior & Systems

49:11 – Meditation & Mental Reprogramming

50:20 – Distributed Computing & Biology

56:15 – Environment Shapes Potential

57:57 – Empowering Individuals at Scale

01:00:31 – Biohacking Meets Inner Awareness

01:04:01 – The Dark Side of DIY Mind Hacks

01:06:09 – Future of Biohacking & Community

01:12:28 – Integrating Genetic & Life Data

01:20:39 – Why We Started Biohacking

01:25:01 – Favorite Current Biohacks

01:31:41 – Final Thoughts & Resources

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Podcast #36:Hacking your Biome with uBiome's Jessica Richman

Podcast #36:Hacking your Biome with uBiome's Jessica Richman

Jessica Richman started and sold her first company after high school. Returning to formal education, she attended Stanford University, where she earned degrees in Economics and Science, Technology & Society (emphasis in computer science). Along the way, she worked for Google, McKinsey, Lehman Brothers, the Grameen Bank, and top-tier Silicon Valley venture firms. Currently a doctoral student at Oxford University, her academic interests include social networks, innovation, collective intelligence, and entrepreneurship. uBiome is the world’s first effort to map the human microbiome with citizen science. While the sequencing of the human genome has provided invaluable knowledge, it is very difficult to change our own genetic makeup. The microbiome, in contrast, is much more easily changed through simple means such as healthful probiotic cultures and other lifestyle interventions. The microbiome thus may provide some of the most important medical breakthroughs of our era. uBiome will ultimately empower participants to manage their microbiomes to improve their health as well as make important scientific discoveries for humanity. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Tammi 201331min

Podcast #35: Bulletproof Your Nervous System with Jay Schroeder

Podcast #35: Bulletproof Your Nervous System with Jay Schroeder

World-class strength and neurological conditioning authority, and creator of new technology that stimulates rapid nervous system and cellular improvements He has studied the greatest training systems of the world, not to find the successes but to establish the point at which they failed. He then put together his system of training to overcome these points of failure. He has traveled to Eastern bloc countries and developed working relationships with some of the most knowledgeable in the field. He has designed unique protocols for use with his device as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. Elite level pro athletes pay more than $50,000 to train with Jay. He has designed unique protocols for use with the ARP as well as the typical equipment in the gym setting, as they relate to rehab strength, injury prevention and elite athletic mastery. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Tammi 201351min

Podcast #34: The Perfect Health Diet with Paul Jaminet

Podcast #34: The Perfect Health Diet with Paul Jaminet

Paul Jaminet. Ph.D. was an astrophysicist at the Harvard-Smithsonian Center for Astrophysics, became a software entrepreneur during the Internet boom, and now provides strategic advice to entrepreneurial companies while pursuing research in economics. Paul’s experience overcoming a chronic illness has been key to his views of aging and disease, and in writing his new book Perfect Diet Solution. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Joulu 201240min

Podcast #33: Injury prevention and Wellness with Dr. Justin Marchegiani

Podcast #33: Injury prevention and Wellness with Dr. Justin Marchegiani

Dr. Justin Marchegiani is a graduate of the University of Massachusetts at Amherst with a B.S. degree in Kinesiology and Pre-medical studies. Dr. Justin has completed his Doctorate degree in Chiropractic Medicine from Life West University. Dr. Justin has completed post graduate study in the area of clinical nutrition, exercise and functional medicine so he can offer the most cutting edge techniques to help address his patient’s growing health care needs. Justin is head of Just In Health Wellness Clinic, a leading systems and functional medical provider who treats patients and athletes using biohacking and quantification. He can help you Bulletproof your game through education on injury prevention and performance enhancement! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Joulu 201236min

Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel

Podcast #32: Hacking your Heart and Preventing Diabetes with Dr. Rocky Patel

Dr. Patel is a Bulletproof Physician.  He is a family physician whose practice is focused on the prevention, early detection and treatment of Diabetes and Heart Attack.  He knows his stuff, he lost over 85 lbs practicing what he preaches. He uses Bulletproof diet principles in treating patients in his practice at risk for or who have developed diabetes and/or cardiovascular disease.   In addition, he is the chief medical officer for Heart Fit for Duty, providing similar services to the first responder community.  For those of you interested in WellnessFx in Arizona, he is a WellnessFX practitioner and his family medical practice is based in Gilbert, Arizona.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Marras 20121h 15min

Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Podcast #31: Hack Your Sleep with Dr. Jonathan Wisor, Ph.D.

Dr. Wisor is one of the foremost researchers on sleep and nervous system function.  His laboratory is funded by both the Department of Defense and the National Institute of Neurological Disorders and Stroke to apply molecular genetic and biochemical techniques to study sleep. Dr. Wisor comes on the show today to talk about how you can use biochemistry and the latest research to improve sleep and your quality of life. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Syys 20121h 16min

Podcast #30: Sweet Potato Power with Ashley Tudor

Podcast #30: Sweet Potato Power with Ashley Tudor

Ashley Tudor is a Design Strategist with the Spruce Street Institute where she works to create innovations in healthcare for doctors, patients and kids. She has worked with a wide range of Fortune 500 companies on a variety of projects including envisioning the future of cars, finding new ways for people to invest their money, designing ways to help food companies fight obesity, and coming up with new medical devices for primary care physicians. Ashley was named one of San Francisco’s Top Innovators in Health in 2010.Aside from her business exploits, Ashley is the author of Sweet Potato Power, a book aimed at promoting what she believes to be one of the healthiest and most high performance foods you can eat.  Ashley comes on Upgraded Self Radio to talk about how you can use the power of sweet potatoes to look, feel, and perform better. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Elo 20121h 12min

Podcast #29: How Real Food Improves Your Performance with Joel Salatin

Podcast #29: How Real Food Improves Your Performance with Joel Salatin

Joel F. Salatin is an American farmer, lecturer, and author whose books include Folks, This Ain't Normal, You Can Farm, and Salad Bar Beef. Salatin raises livestock using holistic methods of animal husbandry, free from harmful chemicals, on his Polyface Farm in Swoope, Virginia, in the Shenandoah Valley. Joel joins us today to talk about his unique farming methods, and why they improve both your health, and the health of the animals. Click here to subscribe to the podcast in iTunes. Click here to read the free transcript of this episode (coming soon). See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Kesä 20121h 20min

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