632nm18 Marras 2024

The Science of Drug Discovery: Insights from Artem Evdokimov

In this episode, drug discovery scientist Artem Evdokimov discusses the science of pharmaceutical development, from historical breakthroughs to the current landscape. He shares insights on antibiotics resistance, the obesity drug Ozempic, and technical details of drug screening methods like DNA-encoded libraries.

The conversation covers the economics of drug development, the potential of AI, and broader philosophical questions about human health and medicine. Evdokimov emphasizes the importance of avoiding oversimplification in science while highlighting both the triumphs and ongoing challenges in pharmaceutical research.

03:18 Historical Roots of Medicine
05:33 Evolution of Drug Delivery Methods
12:52 Modern Drug Discovery and Challenges
45:39 Understanding the Drug Discovery Process
47:30 Challenges in Gene Therapy
49:26 Complexities of Human Physiology
53:14 The Role of Receptors and Hormones
01:28:12 The Selenium Shortage and Shampoo Dilemma
01:28:54 Challenges in Drug Manufacturing and Distribution
01:34:23 Antibiotic Resistance: A Growing Concern
01:45:18 The Future of Drug Discovery and AI
02:11:01 Exploring AI and Drug Discovery
02:11:41 Outsourcing in Pharma: Pros and Cons
02:13:56 High Throughput Screening and Machine Learning
02:16:37 Challenges and Future of Drug Discovery

FOLLOW US ON SOCIAL:
Twitter @ https://x.com/632nmPodcast
Substack: https://632nmpodcast.substack.com/
Michael Dubrovsky @ https://x.com/MikeDubrovsky
Misha Shalaginov @ https://x.com/MYShalaginov
Xinghui Yin @ https://x.com/XinghuiYin

SUBSCRIBE:
Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR

WEBSITE:
https://www.632nm.com

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(52)

Bioelectricity, Morphogenesis, and Two-Headed Worms | Michael Levin

How can a flatworm regenerate a complete head after being cut in half?In this episode, we speak with Michael Levin, developmental biologist and director of the Allen Discovery Center at Tufts Universi...

2 Kesä 1h 27min

Quantum Architecture, QAOA, and Cancer Biomarkers | Fred Chong

Are quantum computers changing the way we discover cancer treatments?In this episode, Misha and Yudong spoke with Fred Chong, Seymour Goodman Professor at the University of Chicago, about the future o...

19 Touko 1h 59min

How Quantum Sensors Can Measure Single Electrons | Amir Yacoby

How do you measure something as small as a single electron or map quantum behavior at the nanoscale?In this episode, Misha spoke with Amir Yacoby, professor at Harvard University, about the cutting ed...

5 Touko 2h 1min

The Physics of Un-Hackable Face Recognition | Rob Devlin on Metalenz

How do you turn a flat piece of nanostructured material into a secure biometric sensor?In this episode, we speak with Rob Devlin, co-founder and CEO of Metalenz, about how metasurfaces are transformin...

21 Huhti 1h 13min

The Real Economics of Data Centers in Space | Starcloud CEO Philip Johnston

Are data centers in space physically possible, or just another overhyped idea?In this episode, we speak with Philip Johnston, CEO of Starcloud, about the technical and economic case for putting AI inf...

1 Huhti 1h 37min

How To Make Quantum Algorithms Cheaper | Craig Gidney on Magic-State Factories, Resource Estimates

How do you actually make quantum algorithms work on real hardware?Build your own quantum circuits in Crumble: https://algassert.com/crumbleIn this episode, we speak with Craig Gidney of Google Quantum...

27 Maalis 2h 3min

How Neurons Translate Electricity into Chemistry | Tom Südhof

How do neurons convert electrical signals into chemical messages in under a millisecond?In this episode, we speak with Thomas Südhof, Stanford neuroscientist and Nobel laureate whose discoveries revea...

10 Maalis 1h 30min

How Engineers Solve “Impossible” Problems | Dan Gelbart

How do engineers solve problems that seem to violate the laws of physics?In this episode, we speak with Dan Gelbart, a prolific inventor and precision engineer, about what it really means to work at t...

17 Helmi 2h 3min