The Science & Art of Comedy & Creativity | Tom Segura
Huberman Lab19 Touko 2025

The Science & Art of Comedy & Creativity | Tom Segura

My guest is Tom Segura, renowned comedian, writer, actor and director. We discuss the “how-to” of comedy writing and storytelling, and what the science of humor and the creative process reveal about human emotion and memory. We explore why surprise and the act of "saying the unspoken truth" activate the brain’s reward circuits, as well as the subconscious mechanisms that shape our sense of what is funny. The episode also examines the bi-directional influence between comedy and cultural standards. It will interest anyone curious about the science of humor, the art of performance and emotional contagion. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui: https://mauinuivenison.com/huberman Helix Sleep: https://helixsleep.com/huberman David Protein: https://davidprotein.com/huberman Function Health: https://functionhealth.com/huberman Timestamps 00:00:00 Tom Segura 00:01:45 Family, Sports, Running 00:09:35 Sponsors: Maui Nui & Helix Sleep 00:12:37 Ideas, Running, Sleep & Brain, Tools: Exercise for Energy; Phone Outside Room 00:20:16 Capturing Ideas, Cannabis, Storytelling, Experimentation 00:27:28 Ideas & Set List, Performance 00:31:52 Wife, Jokes, Reframing Content; Cancel Culture, Audience Reaction 00:40:56 Jokes, Self & Amusement; Evolution & New Material 00:48:26 Sponsors: AG1 & David Protein 00:51:24 Surprise, Hidden Thoughts; Acting 00:59:02 Voice Impersonation, Kids, Strength Training, Activities 01:05:40 Repeating Jokes; State Changes, Crowds & Energy 01:13:11 Silly Mindset; Audience, Emotional Contagion; Humor & Subconscious Mind 01:27:44 Sponsor: Function 01:29:32 Crowd Work, Comedy Clubs; Original Comedy 01:38:13 Comedy & Social Context; Dark Comedy 01:47:51 Drugs, Overdose, Comedian Deaths, Mental Health; Cynicism, Hope 01:54:21 Audience, Twin Comics; Vulnerability; Stand-Up & Performance 02:01:49 Comedy & Passion, Complaints; Childhood Struggle, Insecurities, Therapy 02:10:53 “Bad Thoughts” Show, Upcoming Projects 02:14:44 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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How to Find & Be a Great Romantic Partner | Lori Gottlieb

How to Find & Be a Great Romantic Partner | Lori Gottlieb

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7 Huhti 20253h 24min

Essentials: Lose Fat With Science-Based Tools

Essentials: Lose Fat With Science-Based Tools

In this Huberman Lab Essentials episode, I explore how the nervous system impacts fat loss and how certain behaviors and supplements can accelerate fat burning. I explain how non-exercise movements l...

3 Huhti 202538min

Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improv...

31 Maalis 20253h 13min

Essentials: How to Learn Skills Faster

Essentials: How to Learn Skills Faster

In this Huberman Lab Essentials episode, I explore how to improve motor skill learning and proficiency—whether for athletic performance, learning an instrument or refining any physical skill. I expla...

27 Maalis 202534min

How to Improve Your Teeth & Oral Microbiome for Brain & Body Health | Dr. Staci Whitman

How to Improve Your Teeth & Oral Microbiome for Brain & Body Health | Dr. Staci Whitman

My guest is Dr. Staci Whitman, DMD, a board-certified dentist for kids and adults. We discuss the critical importance of oral care and the oral microbiome for brain and bodily health. We examine the n...

24 Maalis 20252h 55min

Essentials: Supercharge Exercise Performance & Recovery with Cooling

Essentials: Supercharge Exercise Performance & Recovery with Cooling

In this Huberman Lab Essentials episode, I discuss the critical role of temperature regulation in optimizing athletic and physical performance. I explain why overheating can hinder performance and en...

20 Maalis 202533min

How to Increase Your Speed, Mobility & Longevity with Plyometrics & Sprinting | Stuart McMillan

How to Increase Your Speed, Mobility & Longevity with Plyometrics & Sprinting | Stuart McMillan

My guest is Stuart McMillan, a renowned track and field coach who has trained dozens of Olympic medalists, professional athletes, and team coaches across a diverse range of sports. We discuss how to u...

17 Maalis 20253h 1min

Essentials: Boost Your Energy & Immune System with Cortisol & Adrenaline

Essentials: Boost Your Energy & Immune System with Cortisol & Adrenaline

In this Huberman Lab Essentials episode, I explain how specific hormones influence both energy levels and the immune system and discuss practical tools for increasing energy throughout the day and man...

13 Maalis 202536min

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