Ep. 353: Trigger Happy: The MCAS (Mast Cell Activation Syndrome) Episode with Dr. Zac Spiritos

In this episode of The Birth Lounge podcast, HeHe shares her 5-year struggle with Mast Cell Activation Syndrome (MCAS), a condition where mast cells release chemicals like histamine inappropriately. She is sharing all the details about how diagnosing MCAS has been complicated, if not impossible in the allopathic care system, and describes her personal journey, including a surprising reprieve during pregnancy. In this episode, HeHe chats with Dr. Zac Spiritos, a neuro gastroenterologist, in a conversation about MCAS, its symptoms, triggers, and management. Dr. Zac provides an in-depth look at MCAS, comparing it to histamine intolerance and systemic mastocytosis, and discusses potential causes and common diagnostic tests. The dialogue also covers the impact of diets, the role of the immune system, and the complexities involved in treating such conditions. Insights into Dr. Zac's holistic approach and upcoming telehealth clinic for complex digestive disorders are also shared, providing valuable information for listeners navigating similar health challenges.

00:00 Introduction and Medication Dilemma

01:00 HeHe’s Journey with MCAS

01:31 Understanding Mast Cell Activation Syndrome (MCAS)

02:32 Challenges in Diagnosing MCAS

04:34 Introducing Dr. Zac Spiritos

06:07 MCAS Symptoms and Triggers

07:49 MCAS Management and Treatment Options

16:14 MCAS and Pregnancy

23:56 Neuro Gastroenterology Explained

28:17 The Brain-Gut Connection

30:02 Understanding GI Health and MCAS

30:56 Histamine Intolerance Explained

31:52 Mast Cell Activation Syndrome (MCAS)

33:17 Systemic Mastocytosis and Testing

36:35 High Histamine Foods and Diet Management

47:21 Genetics and Environmental Triggers

49:13 Conclusion and Resources

Guest Bio:

Dr. Zac Spiritos is a Neurogastroenterologist and is the co-founder of EverBetter Medicine, a holistic telehealth clinic specializing in complex digestive conditions, dysautonomia, and medical weight management. The practice combines evidence-based medicine with personalized care, focusing on nutrition, movement, nervous system regulation, and targeted therapies. EverBetter Medicine is built on the belief that patients deserve time, attention, and a comprehensive approach to healing—because feeling better starts with being heard.

INSTAGRAM:

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LINKS MENTIONED:

https://everbettermedicine.health/