Ep 50 Antibiotics: We owe it all to chemistry!

Ep 50 Antibiotics: We owe it all to chemistry!

Fifty episodes. That’s fifty (sometimes) deadly viruses, bacteria, protozoa, parasites, and poisons. And don’t forget the fifty quarantinis to accompany each! What better way to celebrate this momentous occasion than talking about something that may actually save you: antibiotics. In this, our golden anniversary episode, our ambition tempts us to tackle the massive world of these bacteria-fighting drugs. We explore the various ways that antibiotics duel with their bacterial enemies to deliver us from infection, and we trace their history, from the early years of Fleming and Florey to the drama-laden labs of some soil microbiologists. Finally, we end, as we always do, with discussing where we stand with antibiotics today. Dr. Jonathan Stokes (@ItsJonStokes), postdoctoral fellow in Dr. Jim Collins’ lab at MIT, joins us to talk about some of his lab’s amazing research on using machine learning to discover new antibiotics, which prompts us to repeat “that is SO COOL” and “we are truly living in the future.” We think you’ll agree.

To read more about using machine learning to uncover antibiotic compounds, head to the Collins’ lab website, the Audacious Project site, or check out Dr. Stokes’ paper:

Stokes, Jonathan M., et al. "A deep learning approach to antibiotic discovery." Cell 180.4 (2020): 688-702.

See omnystudio.com/listener for privacy information.

Jaksot(281)

Special Episode: Dr. Lindsey Fitzharris and Adrian Teal & Dead Ends!

Special Episode: Dr. Lindsey Fitzharris and Adrian Teal & Dead Ends!

Science doesn’t always get it right the first time (or the second, or the third, or even the ninety-ninth!). And while we may chuckle at the outlandish things people believed or the goofy experiments ...

28 Loka 202554min

Ep 191 Famine: More than starvation

Ep 191 Famine: More than starvation

As we learned last week, starvation extends far beyond hunger and what a lack of food does to the human body. Similarly, famine is much more than a food shortage and starvation on a population-level s...

21 Loka 20251h 10min

Ep 190 Starvation: More than hunger

Ep 190 Starvation: More than hunger

Deprived of food, our bodies do the best they can to keep us alive and functioning as long as possible. As the days pass, the rhythms of our lives change: our metabolism, our heartbeats, our hormones,...

14 Loka 20251h 4min

Special Episode: Antonia Hylton & Madness

Special Episode: Antonia Hylton & Madness

The United States is in the midst of a monumental mental health crisis, with one in four people predicted to experience mental illness at some point in their lives. Adequate mental health care remains...

7 Loka 202556min

Ep 189 Newborn screening: The future is here

Ep 189 Newborn screening: The future is here

Every year, millions of babies around the world are screened for dozens of treatable conditions within the first day or two of life. What it takes is a few drops of blood on some filter paper, and wha...

30 Syys 20251h 18min

Ep 188 Candida yeast: Here, there, and everywhere

Ep 188 Candida yeast: Here, there, and everywhere

None of us are ever truly alone. Our bodies are home to untold numbers of microbes, chilling on our skin, in our guts, throughout our respiratory tract, inside our bellybuttons, under our fingernails,...

23 Syys 20251h 17min

Special Episode: Mary Roach & Replaceable You

Special Episode: Mary Roach & Replaceable You

When your car breaks down or your fridge goes on the fritz, you can order a replacement part and get things back up and running in no time. The same cannot always be said for another intricate machine...

16 Syys 202548min

Ep 187 Hypothermia Part 2: How it helps

Ep 187 Hypothermia Part 2: How it helps

Last week, we took you through all the ways that cold can harm us and the harrowing history of humans perishing at its icy hands. Ending the story there would be skipping over the parts where cold get...

9 Syys 20251h 5min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-duodecim-lehti
rss-kasvikutsut
mielipaivakirja
rss-poliisin-mieli
rss-kasvatuspsykologiaa-kaikille
utelias-mieli
docemilia
vinkista-vihia
rss-ranskaa-raakana
rss-ammamafia
rss-astetta-parempi-elama-podcast
rss-tiedetta-vai-tarinaa