Ep 51 The Path of Most (Antibiotic) Resistance

Ep 51 The Path of Most (Antibiotic) Resistance

No story of antibiotics would be complete without the rise of resistance. As promised in our last episode, this week we dive into what the WHO calls ‘one of the biggest threats to global health, food security, and development today’ - antibiotic resistance. In the decades since their development, misuse and overuse of antibiotics has led to many becoming all but useless, and our world seems on the verge of plunging into a post-antibiotic era. How does resistance work? Where did it come from? Why did it spread so far so rapidly? Is there any hope? In this episode, we answer all these questions and more. First, we explore the many ways bacteria evade the weaponry of antibiotic compounds. Then we trace the global spread of these resistant bugs by examining the major contributors to their misuse and overuse. And finally we assess the current global status of antibiotic resistant infections (spoiler: it’s very bad) and search for any good news (spoiler: there’s a lot!). To chat about one super cool and innovative alternative to antibiotics, we are joined by the amazing Dr. Steffanie Strathdee (Twitter: @chngin_the_wrld), Associate Dean of Global Health Sciences, Harold Simon Professor at the University of California San Diego School of Medicine and Co-Director at the Center for Innovative Phage Applications and Therapeutics. Dr. Strathdee provides a firsthand account of helping her husband, Dr. Tom Patterson, fight off a deadly superbug infection by calling on a long-forgotten method of treating bacterial infections: phage therapy.

To read more about phage therapy and Dr. Strathdee’s incredible experiences, check out The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir.

See omnystudio.com/listener for privacy information.

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Ep 219 The Brown Recluse: Fearsome foe or slandered spider?

Ep 219 The Brown Recluse: Fearsome foe or slandered spider?

Few spiders hold the dubious honor of name recognition among the general public. Most that do, like black widows, Australian funnel-web, the Goliath birdeater, are renowned not for their cute colors o...

18 Elo 58min

Special Episode: Deborah Cohen & Bad Influence

Special Episode: Deborah Cohen & Bad Influence

If you have a medical question, where do you turn? How often is google or social media your first stop? As you sift through the AI overview and countless reels professing to have the answers, it becom...

11 Elo 51min

Ep 218 The Lowdown on Statins

Ep 218 The Lowdown on Statins

Last week, we set the stage by breaking down the science behind cholesterol: how it moves through our body, why it causes disease, and when we discovered the link between LDL and atherosclerosis. This...

4 Elo 1h 10min

Ep 217 The High Stakes of Cholesterol

Ep 217 The High Stakes of Cholesterol

So your latest blood test results have come in, and you see a couple of numbers for cholesterol. What do those numbers mean, and why do we care about them? In this first part of our cholesterol minise...

28 Heinä 1h 3min

Ep 216 Cyclospora: Explosive Diarrhea Everywhere

Ep 216 Cyclospora: Explosive Diarrhea Everywhere

You’ve seen the headlines: a food-borne parasite is infecting people across the US, leaving them chained to the toilet sometimes for weeks on end, as they are ravaged by wave after wave of gastrointes...

21 Heinä 54min

Special Episode: Alev Scott & Cash Cow

Special Episode: Alev Scott & Cash Cow

Social media ads for egg freezing. A craigslist-like site for breast milk. Fertility fairs featuring IVF clinics alongside shamanic nutritionists. Surrogacy contracts offering a discount for multiple ...

14 Heinä 48min

Ep 215 The Hidden Depths of Earwax

Ep 215 The Hidden Depths of Earwax

In keeping with last week’s theme of “bodily excretions that are kinda gross that you don’t really think about but are actually really important”, we’re devoting this episode to earwax, aka cerumen. I...

7 Heinä 54min

Ep 214 Boogers: Digging for treasure

Ep 214 Boogers: Digging for treasure

Hard and crusty. Green and gloopy. Clear and watery. Boogers come in a veritable rainbow of colors and a full spectrum of textures from liquid to solid. They’re really quite impressive if you think ab...

30 Kesä 1h 2min

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