Core IM | Internal Medicine Podcast25 Kesä 2025

#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all.

Listen to this latest episode of Beyond Journal Club, a collaboration between Core IM and NEJM Group, where we put research into context tracing the arc of evidence, dissecting the clinical question, and exploring what the findings could mean for real-world patient care

🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply!

🔹 Transcript and Show Notes

Timestamps:

(00:48) | Background on Beta Blockers and Their Mechanism

(02:41) | Historical Context of Beta Blockers in Heart Disease

(04:56) | Capricorn Trial and Its Impact

(07:17) | Emergence of Doubts About Beta Blockers

(10:09) | Introduction to the REDUCED-AMI Trial

(15:52) | Discussion on Trial Interpretation and Clinical Implications

(16:18) | Comparison with Other Trials and Future Directions

Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Cardiology

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out CovePure and use my code CovePure.com/coreim for a great deal: https://covepure.com
* Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io
* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com
* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim
* Get 15% off Branch Basics with the code COREIM at https://branchbasics.com/COREIM #branchbasicspod

Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(219)

#211 Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment

MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When...

29 Kesä 33min

#210 HTN in Dialysis: 5 Pearls Segment

What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practica...

17 Kesä 25min

#209 Dialysis and Fluid Management: 5 Pearls Segment

Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hy...

10 Kesä 31min

#208 AI vs. Human with Post-Op AFib: Bread & Butter Series

Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clini...

27 Touko 29min

#207 Is There a Doctor on Board? In-Flight Emergencies

We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when pla...

18 Touko 27min

#206 Eosinophilia: 5 Pearls Segment

Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside?In this high-yield episode, test your clinical reasoning as we tackle:When eosinophi...

28 Huhti 43min

#205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group

Is coffee helping or harming our patients’ hearts?In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question:How should clinicians interpret nutrition rese...

15 Huhti 32min

#204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment

Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical s...

1 Huhti 33min