CELMoDs for the treatment of non-Hodgkin lymphoma
Lymphoma Hub3 Heinä 2025

CELMoDs for the treatment of non-Hodgkin lymphoma

During the Lymphoma Hub Steering Committee Meeting, Gilles Salles, Memorial Sloan Kettering Cancer Center, New York, US, chaired a discussion on cereblon E3 ligase modulators (CELMoDs) for the treatment of non-Hodgkin lymphoma.


This discussion also featured Grzegorz Nowakowski, Sonali Smith, Ulrich Jäger, Catherine Thieblemont, Michael Dickinson, Francesc Bosch, Miles Prince, and Marek Trněný.


Prior to the discussion, Salles presented an overview of CELMoDs, highlighting their mechanism of action and introducing golcadomide as a novel agent under investigation for lymphomas. He reviewed emerging clinical data from early-phase trials evaluating golcadomide and iberdomide in relapsed/refractory non-Hodgkin lymphoma, including monotherapy and combinations with monoclonal antibodies. Additionally, he outlined the ongoing phase III GOLSEEK-1 and phase II GOLSEEK-2 trials investigating golcadomide in combination with rituximab-cyclophosphamide-doxorubicin-vincristine-prednisone (R-CHOP) for high-risk large B-cell lymphoma and with rituximab for newly diagnosed advanced-stage follicular lymphoma, respectively.


This educational resource is independently supported by Bristol Myers Squibb. All content was developed by SES in collaboration with an expert steering committee; funders were allowed no influence on the content of this resource.

Hosted on Acast. See acast.com/privacy for more information.

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(44)

ASH 2025 | Key highlights in lymphoma and CLL

ASH 2025 | Key highlights in lymphoma and CLL

During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the Lymphoma Hub was pleased to speak with Joshua Brody from the Icahn School of Me...

22 Joulu 20257min

ASH 2025 | Latest updates from the phase I NX-5948-301 trial of bexobrutideg in patients with R/R CLL

ASH 2025 | Latest updates from the phase I NX-5948-301 trial of bexobrutideg in patients with R/R CLL

During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the Lymphoma Hub was pleased to speak with Alexey Danilov, City of Hope Comprehensi...

18 Joulu 20254min

What do the clinical data tell us about fixed-duration ibrutinib + venetoclax for patients with CLL?

What do the clinical data tell us about fixed-duration ibrutinib + venetoclax for patients with CLL?

The Lymphoma Hub was pleased to speak to Susan O’Brien, Chao Family Comprehensive Cancer Center, University of California, Irvine, US. We asked, What do the clinical data tell us about fixed-duration ...

17 Joulu 20257min

ASH 2025 | EPCORE FL-1 phase III primary results: Epcoritamab with rituximab + lenalidomide (R2) vs R2 alone for R/R FL

ASH 2025 | EPCORE FL-1 phase III primary results: Epcoritamab with rituximab + lenalidomide (R2) vs R2 alone for R/R FL

During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the Lymphoma Hub was pleased to speak with Lorenzo Falchi, Memorial Sloan Kettering...

11 Joulu 20256min

ASH 2025 | 3-year follow-up results from the STARGLO trial of Glofit-GemOx vs R-GemOx in R/R DLBCL

ASH 2025 | 3-year follow-up results from the STARGLO trial of Glofit-GemOx vs R-GemOx in R/R DLBCL

During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the Lymphoma Hub was pleased to speak with Haifaa Abdulhaq, University of Californi...

10 Joulu 20254min

ASH 2025 | Epcoritamab for R/R DLBCL: Results from EPCORE NHL-6, by race and ethnicity

ASH 2025 | Epcoritamab for R/R DLBCL: Results from EPCORE NHL-6, by race and ethnicity

During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the Lymphoma Hub was pleased to speak with Adelba Torres, Hospital Auxilio Mutuo, S...

10 Joulu 20252min

Glofit-GemOx vs R-GemOx in patients with R/R DLBCL: Results from the STARGLO trial

Glofit-GemOx vs R-GemOx in patients with R/R DLBCL: Results from the STARGLO trial

During the Lymphoma Hub Steering Committee Meeting on October 6, 2025, key opinion leaders met to discuss the results from the phase III STARGLO trial (NCT04408638) of glofitamab (Glofit) + gemcitabin...

5 Joulu 202536min

What factors influence BTKi + BCL-2i treatment selection for patients with CLL?

What factors influence BTKi + BCL-2i treatment selection for patients with CLL?

The Lymphoma Hub was pleased to speak to Francesc Bosch, Vall d'Hebron Barcelona Hospital Campus, Barcelona, ES. We asked, what factors influence Bruton’s tyrosine kinase inhibitor (BTKi) + B-cell lym...

5 Marras 20257min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
psykopodiaa-podcast
voi-hyvin-meditaatiot-2
rss-rahamania
rss-koira-haudattuna
rss-narsisti
psykologia
rss-liian-kuuma-peruna
kesken
rss-hereilla
taytta-tavaraa
rahapuhetta
rss-duodecim-lehti
rss-radplus
rss-arkea-ja-aurinkoa-podcast-espanjasta
rss-niinku-asia-on
rss-valo-minussa-2
rss-vapaudu-voimaasi
dear-ladies
rss-eron-alkemiaa