#153 – Dmitry Korkin: Evolution of Proteins, Viruses, Life, and AI
Dmitry Korkin is a professor of bioinformatics and computational biology at WPI. Please support this podcast by checking out our sponsors: - Brave: https://brave.com/lex - NetSuite: http://netsuite.com/lex to get free product tour - Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off - Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Dmitry's Website: http://korkinlab.org/ Dmitry's Twitter: https://twitter.com/dmkorkin PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:21) - Proteins and the building blocks of life (14:23) - Spike protein (21:11) - Coronavirus biological structure explained (26:09) - Virus mutations (32:39) - Evolution of proteins (42:25) - Self-replicating computer programs (50:02) - Origin of life (57:34) - Extraterrestrial life in our solar system (59:31) - Joshua Lederberg (1:05:30) - Dendral (1:08:24) - Why did expert systems fail? (1:10:35) - AlphaFold 2 (1:32:13) - Will AI revolutionize art and music? (1:39:12) - Multi-protein folding (1:43:39) - Will AlphaFold 2 result in a Nobel Prize? (1:46:10) - Will AI be used to engineer deadly viruses? (2:01:17) - Book recommendations (2:11:00) - Family (2:13:38) - A poem in Russian
11 Tammi 20212h 18min
#152 – Dan Gable: Olympic Wrestling, Mental Toughness & the Making of Champions
Dan Gable is one of the greatest Olympic athletes and wrestling coaches of all time. Please support this podcast by checking out our sponsors: - Tryolabs: https://tryolabs.com/lex - ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free - Grammarly: https://grammarly.com/lex to get 20% off premium - SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera EPISODE LINKS: Dan's Twitter: https://twitter.com/dannygable Dan's Website: https://dangable.com/ Dan's Books: https://amzn.to/2VK5nbn PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:31) - Russian wrestling (11:09) - Coaching the science, art, and toughness of wrestling (18:05) - The pain of defeat and the tattoo of a hawk clawing out the heart (21:04) - Roger Bannister and the 4 minute mile (24:09) - The dream of becoming an Olympic champion (26:38) - The day in 1972 of the Olympic final (30:10) - Sauna story (31:39) - Match against the Russian (37:13) - The role of fear in wrestling (42:14) - The line between physical wrestling and anger (46:53) - Tragic loss of Dan's sister (54:21) - The role of family in wrestling (59:43) - Wrestling being voted out of the Olympics (1:04:26) - To beat the best you must study the best (1:09:39) - The role of luck (Old Man and the Sea)
9 Tammi 20211h 16min
#151 – Dan Kokotov: Speech Recognition with AI and Humans
Dan Kokotov is VP of Engineering at Rev.ai, an automatic speech recognition company. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium - Business Wars: https://wondery.com/business-wars/ - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Rev: https://www.rev.com Rev.ai: https://www.rev.ai PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:17) - Dune (12:34) - Rev (18:33) - Translation (25:22) - Gig economy (34:02) - Automatic speech recognition (44:53) - Create products that people love (53:02) - The future of podcasts at Spotify (1:14:41) - Book recommendations (1:16:02) - Stories of our dystopian future (1:19:45) - Movies about Stalin and Hitler (1:24:59) - Interviewing Putin (1:30:56) - Meaning of life
4 Tammi 20211h 34min
#150 – Michael Malice: The White Pill, Freedom, Hope, and Happiness Amidst Chaos
Michael Malice is a political thinker, podcaster, and author. Please support this podcast by checking out our sponsors: - NetSuite: http://netsuite.com/strategy to get free product tour - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Michael's Twitter: https://twitter.com/michaelmalice Michael's Community: https://malice.locals.com/ Michael's YouTube: https://www.youtube.com/channel/UC5tj5QCpJKIl-KIa4Gib5Xw Michael's Website: http://michaelmalice.com/about/ Your Welcome podcast: https://bit.ly/30q8oz1 The New Right (book): https://amzn.to/34gxLo3 Dear Reader (book): https://amzn.to/2HPPlHS Podcast (Round 1): https://www.youtube.com/watch?v=BIk1zUy8ehU PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:47) - Conversation with Alex Jones and Tim Pool (18:31) - Michael's outfit (26:53) - Self-publishing a book (36:41) - The white pill (48:05) - What did the volcano say to his true love? (49:28) - Myth of Sisyphus (53:09) - Journalism failed to stop Stalin and Hitler (1:00:53) - Good Germans (1:04:49) - Richard Wolff (1:08:20) - Could United States have stayed out of World War II (1:11:12) - Trump Derangement Syndrome (1:12:58) - Nazism and Antisemitism (1:15:40) - Knock knock (1:22:20) - Putin (1:30:00) - The evil of Kim Jong-il and North Korea (1:38:32) - Dark humor (1:43:18) - Comedy is tragedy plus timing (1:50:34) - Interviewing difficult guests (2:00:06) - Curtis Yarvin (Mencius Moldbug) (2:16:24) - Violence under anarchism (2:31:58) - Ayn Rand (2:35:07) - Secession in United States (2:44:46) - Politics over next 4 years (2:52:14) - Mars (2:56:17) - UFOs (2:59:12) - Psychedelics (3:03:08) - What is love?
31 Joulu 20203h 9min
#149 – Diana Walsh Pasulka: Aliens, Technology, Religion, and the Nature of Belief
Diana Walsh Pasulka is a professor of philosophy and religion at UNCW and author of American Cosmic: UFOs, Religion, and Technology. Please support this podcast by checking out our sponsors: - LMNT: https://drinkLMNT.com/lex to get free shipping - Grammarly: https://grammarly.com/lex to get 20% off premium - Business Wars: https://wondery.com/business-wars/ - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Diana's Website: https://uncw.edu/par/faculty/faculty-pasulka.html American Cosmic (book): https://amzn.to/3aK2kaj PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (08:28) - What is real? (13:56) - Can beliefs become reality? (18:59) - Donald Hoffman (22:57) - Immanuel Kant's Critique of Pure Reason (26:27) - Ayn Rand (33:25) - How do religions start? (48:38) - Religion is an evolutionary advantage (53:59) - Religion used in propaganda (58:32) - What did Nietzsche mean by "God is Dead"? (1:03:59) - American Cosmic (1:07:45) - What do aliens look like? (1:16:28) - History of space programs (1:19:30) - Jacques Vallee (1:28:55) - Artificial intelligence (1:34:25) - Ufology community (1:45:38) - Psychedelics (1:49:35) - Tic Tac UFO (1:58:09) - Roswell UFO incident (2:09:14) - Bob Lazar (2:12:50) - Monoliths in the desert (2:23:39) - Humans will co-evolve with AI (2:26:58) - Neuralink (2:31:48) - Singularity (2:41:39) - Books: Nietzsche (2:46:44) - Books: Hannah Arendt (2:51:43) - Fear of death (2:56:11) - Meaning of life
28 Joulu 20203h 1min
#148 – Charles Isbell and Michael Littman: Machine Learning and Education
Charles Isbell is the Dean of the College of Computing at Georgia Tech. Michael Littman is a computer scientist at Brown University. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings - MasterClass: https://masterclass.com/lex to get 2 for price of 1 - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Charles's Twitter: https://twitter.com/isbellHFh Charles's Website: https://www.cc.gatech.edu/~isbell/ Michael's Twitter: https://twitter.com/mlittmancs Michael's Website: https://www.littmania.com/ Michael's YouTube: https://www.youtube.com/user/mlittman PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:51) - Is machine learning just statistics? (12:14) - NeurIPS vs ICML (14:30) - Data is more important than algorithm (20:14) - The role of hardship in education (28:57) - How Charles and Michael met (33:30) - Key to success: never be satisfied (36:47) - Bell Labs (48:15) - Teaching machine learning (58:25) - Westworld and Ex Machina (1:06:24) - Simulation (1:13:14) - The college experience in the times of COVID (1:41:52) - Advice for young people (1:48:44) - How to learn to program (2:00:07) - Friendship
26 Joulu 20202h 3min
#147 – Dmitri Dolgov: Waymo and the Future of Self-Driving Cars
Dmitri Dolgov is the CTO of Waymo, an autonomous vehicle company. Please support this podcast by checking out our sponsors: - Tryolabs: https://tryolabs.com/lex - Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium - BetterHelp: https://betterhelp.com/lex to get 10% off - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Waymo's Twitter: https://twitter.com/waymo Waymo's Website: https://waymo.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:46) - Computer games (12:52) - Childhood (15:24) - Robotics (16:14) - Moscow Institute of Physics and Technology (18:26) - DARPA Urban Challenge (28:46) - Waymo origin story (44:27) - Waymo self-driving hardware (53:00) - Connected cars (58:53) - Waymo fully driverless service in Phoenix (1:03:14) - Getting feedback from riders (1:11:28) - Creating a product that people love (1:17:18) - Do self-driving cars need to break the rules like humans do? (1:24:03) - Waymo Trucks (1:29:41) - Future of Waymo (1:42:53) - Role of lidar in autonomous driving (1:55:53) - Machine learning is essential for autonomous driving (1:59:55) - Pedestrians (2:06:32) - Trolley problem (2:11:00) - Book recommendations (2:22:26) - Meaning of life
20 Joulu 20202h 28min
#146 – Michael Mina: Rapid Testing, Viruses, and the Engineering Mindset
Michael Mina is an immunologist, epidemiologist, and physician at Harvard. Please support this podcast by checking out our sponsors: - Brave: https://brave.com/lex - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Michael's Twitter: https://twitter.com/michaelmina_lab Michael's Time article: https://time.com/5912705/covid-19-stop-spread-christmas/ Rapid Tests: https://www.rapidtests.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:28) - Interacting between viruses and bacteria (11:42) - Deadlier viruses (15:13) - Will COVID-19 mutate? (16:47) - Rapid testing (34:11) - PCR vs rapid antigen tests (43:55) - Medical industrial complex (47:47) - Lex takes COVID test (54:32) - FDA and cheap tests (57:17) - Explanation of Elon Musk's positive COVID tests (1:04:25) - Role of testing during vaccine deployment (1:07:54) - Public health policy (1:17:34) - A weather system for viruses (1:34:26) - Can a virus kill all humans? (1:40:05) - Engineering a deadly virus (1:44:47) - AlphaFold 2 and viruses (1:50:42) - Advice for young people (1:58:50) - Time as a Buddhist monk (2:04:54) - Meditation (2:12:32) - Meaning of life
19 Joulu 20202h 19min
