#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep475-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/demis-hassabis-2-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Demis's X: https://x.com/demishassabis DeepMind's X: https://x.com/GoogleDeepMind DeepMind's Instagram: https://instagram.com/GoogleDeepMind DeepMind's Website: https://deepmind.google/ Gemini's Website: https://gemini.google.com/ Isomorphic Labs: https://isomorphiclabs.com/ The MANIAC (book): https://amzn.to/4lOXJ81 Life Ascending (book): https://amzn.to/3AhUP7z SPONSORS: To support this podcast, check out our sponsors & get discounts: Hampton: Community for high-growth founders and CEOs. Go to https://joinhampton.com/lex Fin: AI agent for customer service. Go to https://fin.ai/lex Shopify: Sell stuff online. Go to https://shopify.com/lex LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex AG1: All-in-one daily nutrition drink. Go to https://drinkag1.com/lex OUTLINE: (00:00) - Introduction (00:29) - Sponsors, Comments, and Reflections (08:40) - Learnable patterns in nature (12:22) - Computation and P vs NP (21:00) - Veo 3 and understanding reality (25:24) - Video games (37:26) - AlphaEvolve (43:27) - AI research (47:51) - Simulating a biological organism (52:34) - Origin of life (58:49) - Path to AGI (1:09:35) - Scaling laws (1:12:51) - Compute (1:15:38) - Future of energy (1:19:34) - Human nature (1:24:28) - Google and the race to AGI (1:42:27) - Competition and AI talent (1:49:01) - Future of programming (1:55:27) - John von Neumann (2:04:41) - p(doom) (2:09:24) - Humanity (2:12:30) - Consciousness and quantum computation (2:18:40) - David Foster Wallace (2:25:54) - Education and research PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

Jaksot(481)

#256 – Nationalism Debate: Yaron Brook and Yoram Hazony

#256 – Nationalism Debate: Yaron Brook and Yoram Hazony

Yaron Brook is an objectivist. Yoram Hazony is a national conservative. This is a conversation and debate about national conservatism vs individualism. Please support this podcast by checking out our sponsors: - Noom: https://trynoom.com/lex - InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off - SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera - ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free - Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Yaron's Twitter: https://twitter.com/yaronbrook Yaron's YouTube: https://www.youtube.com/ybrook Yoram's Twitter: https://twitter.com/yhazony Yoram's Website: https://www.yoramhazony.org/ Yaron Brook's Books: In Pursuit of Wealth: https://amzn.to/3qmXuGo Equal Is Unfair: https://amzn.to/3FopKOV Yoram Hazony's Books: Conservatism: https://amzn.to/3sv0Nhe The Virtue of Nationalism: https://amzn.to/3mtxqs6 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:11) - Conservatism (15:07) - Importance of history (27:09) - Rationalism vs empiricism (32:39) - Communism (40:43) - Otto von Bismarck (45:04) - Edmund Burke and the French Revolution (49:52) - USA's founding fathers (1:02:47) - Founding documents (1:24:36) - Cohesion and Individualism (1:45:29) - Love and relationships (1:53:41) - Individual freedom (2:08:08) - Having children (2:21:54) - Reason vs emotions (2:28:44) - Nationalism (2:40:56) - Finding love (2:52:44) - Hope for the future (2:58:08) - Meaning of life

15 Tammi 20223h 4min

#255 – Mark Normand: Comedy!

#255 – Mark Normand: Comedy!

Mark Normand is a stand-up comedian. Please support this podcast by checking out our sponsors: - Calm: https://calm.com/lex to get 40% off - InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off - Onnit: https://lexfridman.com/onnit to get up to 10% off - Grammarly: https://grammarly.com/lex to get 20% off premium - ROKA: https://roka.com/ and use code LEX to get 20% off your first order EPISODE LINKS: Mark's Twitter: https://twitter.com/marknorm Mark's YouTube: https://youtube.com/c/marknormand Out to Lunch (special): https://www.youtube.com/watch?v=tDolNU89SXI The Standups: Season 3 (Netflix): https://www.netflix.com/title/80175685 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (08:45) - Love (11:51) - Childhood in New Orleans (26:37) - New York (35:11) - LA vs NY (44:25) - Advice for new comedians (58:57) - Crafting jokes (1:00:59) - Norm Macdonald (1:08:32) - Favorite medium (1:12:43) - Austin (1:19:04) - Sending people to space (1:20:37) - Robots with human emotion (1:24:08) - Self-driving vehicles (1:28:15) - Future of human interaction (1:32:22) - Advice for young people (1:36:22) - Rapid random questions (1:54:09) - Meaning of life

8 Tammi 20221h 58min

#254 – Jay Bhattacharya: The Case Against Lockdowns

#254 – Jay Bhattacharya: The Case Against Lockdowns

Jay Bhattacharya is a professor of medicine at Stanford University and co-author of the Great Barrington Declaration. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off - Coinbase: https://coinbase.com/lex to get $5 in free Bitcoin - ROKA: https://roka.com/ and use code LEX to get 20% off your first order - Indeed: https://indeed.com/lex to get $75 credit EPISODE LINKS: Jay's Twitter: https://twitter.com/DrJBhattacharya Great Barrington Declaration: https://gbdeclaration.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (10:18) - How deadly is Covid? (39:48) - Covid vs Influenza (45:42) - Francis Collins email to Fauci (1:06:19) - Francis Collins (1:13:48) - Vaccine safety and efficacy (1:20:46) - Vaccine hesitancy (1:37:21) - Great Barrington Declaration and lockdowns (1:53:39) - Focused Protection (2:15:31) - Fear (2:19:57) - Advice for young people (2:24:56) - Fear of death (2:26:53) - Meaning of life

4 Tammi 20222h 28min

#253 – Michael Malice: New Year’s Special

#253 – Michael Malice: New Year’s Special

Michael Malice is a political thinker, podcaster, author, and anarchist. Please support this podcast by checking out our sponsors: - FightCamp: https://joinfightcamp.com/lex to get free shipping - Linode: https://linode.com/lex to get $100 free credit - Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off - Sunbasket: https://sunbasket.com/lex and use code LEX to get $35 off - ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Michael's Twitter: https://twitter.com/michaelmalice Michael's Community: https://malice.locals.com/ Michael's YouTube: https://www.youtube.com/channel/UC5tj5QCpJKIl-KIa4Gib5Xw Michael's Website: http://michaelmalice.com/about/ Your Welcome podcast: https://bit.ly/30q8oz1 Books & resources mentioned: The Anarchist Handbook (book): https://amzn.to/3yUb2f0 The New Right (book): https://amzn.to/34gxLo3 Dear Reader (book): https://amzn.to/2HPPlHS The Idiot (book): https://amzn.to/3zdHdHH Six-Word Memoirs (book): https://amzn.to/3zg51uv PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:07) - Truth, goodness, and beauty (19:35) - Save one life (26:26) - Jeffrey Epstein (45:21) - Jeffrey Epstein and Bill Clinton (51:33) - Christmas and New Years for Russians (58:14) - Russian cynicism and suffering (1:05:52) - Gift exchange (1:18:48) - Michael's move to Austin (1:24:14) - The Anarchist Handbook (1:30:46) - Ghislaine Maxwell (1:35:20) - Jeffrey Epstein (1:37:34) - Lex's move to Austin (1:46:21) - Elon Musk (1:49:31) - Writing The White Pill (1:54:18) - Camus (1:59:16) - Writing The White Pill continued (2:04:34) - New Year's resolutions (2:18:09) - 2024 elections (2:30:38) - National divorce (2:45:15) - Joe Rogan and Bret Weinstein vs Sam Harris (2:54:26) - Conversation with CEO of Pfizer (3:07:59) - Anthony Fauci (3:13:28) - Advice for young people (3:23:30) - Wife and kids (3:28:57) - Immortality

31 Joulu 20213h 32min

#252 – Elon Musk: SpaceX, Mars, Tesla Autopilot, Self-Driving, Robotics, and AI

#252 – Elon Musk: SpaceX, Mars, Tesla Autopilot, Self-Driving, Robotics, and AI

Elon Musk is CEO of SpaceX, Tesla, Neuralink, and Boring Company. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - ButcherBox: https://butcherbox.com/lex to get offers & discounts - InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off - ROKA: https://roka.com/ and use code LEX to get 20% off your first order - Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Elon's Twitter: https://twitter.com/elonmusk PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:38) - Elon singing (08:26) - SpaceX human spaceflight (15:12) - Starship (23:48) - Quitting is not in my nature (25:23) - Thinking process (34:56) - Humans on Mars (40:27) - Colonizing Mars (44:13) - Wormholes (48:50) - Forms of government on Mars (55:54) - Smart contracts (57:24) - Dogecoin (58:55) - Cryptocurrency and Money (1:05:04) - Bitcoin vs Dogecoin (1:07:47) - Satoshi Nakamoto (1:10:10) - Tesla Autopilot (1:13:16) - Tesla Self-Driving (1:25:19) - Neural networks (1:34:16) - When will Tesla solve self-driving? (1:36:19) - Tesla FSD v11 (1:43:53) - Tesla Bot (1:54:33) - History (2:02:24) - Putin (2:08:04) - Meme Review (2:22:29) - Stand-up comedy (2:24:03) - Rick and Morty (2:25:42) - Advice for young people (2:33:39) - Love (2:36:33) - Meaning of life

28 Joulu 20212h 39min

#251 – Ray Dalio: Money, Power, and the Collapse of Empires

#251 – Ray Dalio: Money, Power, and the Collapse of Empires

Ray Dalio is an investor, author, and founder of Bridgewater Associates. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil - GiveWell: https://www.givewell.org/ and use code LEX to get donation matched up to $1k - Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off - Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium - MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Ray's Twitter: https://twitter.com/RayDalio Ray's Instagram: https://www.instagram.com/raydalio Books & resources mentioned: Ray's books: https://amzn.to/3swN5uw Ray's free personality test: https://principlesyou.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (08:14) - Money or power (11:50) - Big Cycle (31:43) - Collapse of the American Empire (40:10) - War (43:18) - Xi Jinping (49:21) - Importance of freedoms (55:24) - Democracy's vulnerability (58:49) - Communism's vulnerability (1:05:50) - Vladimir Putin (1:09:55) - Understanding China (1:17:23) - Henry Kissinger (1:27:44) - Elon Musk and Dogecoin (1:29:41) - How to take notes (1:33:24) - Advice for young people (1:37:30) - Hope for humanity

25 Joulu 20211h 40min

#250 – Peter Wang: Python and the Source Code of Humans, Computers, and Reality

#250 – Peter Wang: Python and the Source Code of Humans, Computers, and Reality

Peter Wang is the co-founder & CEO of Anaconda and one of the most impactful leaders and developers in the Python community. Also, he is a physicist and philosopher. Please support this podcast by checking out our sponsors: - Quip: https://getquip.com/lex to get first refill free - Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off - GiveWell: https://www.givewell.org/ and use code LEX to get donation matched up to $1k - Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off - BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Peter's Twitter: https://twitter.com/pwang Anaconda's Website: https://www.anaconda.com/ Books & resources mentioned: Zen and the Art of Motorcycle Maintenance (book): https://amzn.to/3EnCELK Lila (book): https://amzn.to/30VKIpE PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:49) - Python (10:20) - Programming language design (30:22) - Virtuality (40:22) - Human layers (47:21) - Life (52:45) - Origin of ideas (55:17) - Eric Weinstein (1:00:16) - Human source code (1:04:13) - Love (1:18:32) - AI (1:31:55) - Meaning crisis (1:54:28) - Travis Oliphant (2:00:53) - Python continued (2:30:36) - Best setup (2:37:54) - Advice for the youth (2:46:28) - Meaning of Life

23 Joulu 20212h 53min

#249 – Albert Bourla: Pfizer CEO

#249 – Albert Bourla: Pfizer CEO

Albert Bourla is the Chairman and CEO of Pfizer. Please support this podcast by checking out our sponsors: - Notion: https://notion.com/startups to get up to $1000 off team plan - Calm: https://calm.com/lex to get 40% off - Hunter Douglas: https://www.hunterdouglas.com/lex to get a free design guide - LMNT: https://drinkLMNT.com/lex to get free sample pack - Grammarly: https://grammarly.com/lex to get 20% off premium EPISODE LINKS: Albert's Twitter: https://twitter.com/AlbertBourla Pfizer's Website: https://www.pfizer.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (10:08) - Clinical trials (26:12) - Trust (45:59) - Safety (56:16) - Booster shots (59:09) - Mandates (1:05:39) - Antivirals (1:10:38) - Hope for future

18 Joulu 20211h 14min

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