Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson
Huberman Lab24 Heinä 2025

Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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How Your Thoughts Are Built & How You Can Shape Them | Dr. Jennifer Groh

How Your Thoughts Are Built & How You Can Shape Them | Dr. Jennifer Groh

My guest is Dr. Jennifer Groh, PhD, professor of psychology and neuroscience at Duke University. She explains how our brain encodes sights and sounds and integrates them so we can navigate and underst...

10 Marras 20252h 16min

Essentials: Erasing Fears & Traumas Using Modern Neuroscience

Essentials: Erasing Fears & Traumas Using Modern Neuroscience

In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses. I explain why successful fear treatment requir...

6 Marras 202540min

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

My guest is Dr. David Fajgenbaum, MD, professor of translational medicine and human genetics at the University of Pennsylvania. He explains how, unbeknownst to most doctors, many approved medications ...

3 Marras 20251h 59min

Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular a...

30 Loka 202539min

Improve Your Lymphatic System for Overall Health & Appearance

Improve Your Lymphatic System for Overall Health & Appearance

Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat...

27 Loka 20251h 40min

Essentials: The Science of Gratitude & How to Build a Gratitude Practice

Essentials: The Science of Gratitude & How to Build a Gratitude Practice

In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice. I explain why common gratitude practices (like simp...

23 Loka 202539min

How to Overcome Inner Resistance | Steven Pressfield

How to Overcome Inner Resistance | Steven Pressfield

My guest is Steven Pressfield, author of The War of Art and expert in how to overcome the inner force of "resistance"—the self-sabotaging tendency to procrastinate on your life's most important work t...

20 Loka 20252h 15min

Essentials: How Your Brain Functions & Interprets the World | Dr. David Berson

Essentials: How Your Brain Functions & Interprets the World | Dr. David Berson

In this Huberman Lab Essentials episode, my guest is Dr. David Berson, PhD, a professor of neuroscience at Brown University and an expert on the visual system and circadian biology. We explore how th...

16 Loka 202540min

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