#360: How Liz Parrish Is REWRITING the Rules of Aging (Gene Therapy, Telomeres & The Future of Longevity)

#360: How Liz Parrish Is REWRITING the Rules of Aging (Gene Therapy, Telomeres & The Future of Longevity)

Today, I’m joined by the trailblazing Liz Parrish, a true pioneer in the world of longevity science and regenerative medicine. Liz doesn’t just talk about cutting-edge gene therapies—she’s the first patient to actually undergo many of them herself. In our conversation, Liz shares how her journey from stem cell advocacy to biotech innovation was fueled by a deeply personal mission: her son’s diagnosis with type 1 diabetes.

What we discuss:

How Liz Parrish got into genetics and stem cells ... 00:06:45

Transition from childhood disease to treating aging ... 00:09:35

Difference between stem cells, gene therapy, and exosomes ... 00:14:20

Challenges in gene therapy delivery and cell reprogramming ... 00:19:22

Liz Parrish as patient zero for gene therapies ... 00:22:01

Results and lessons from Parrish’s self-experimentation ... 00:23:16

Senescent cells, telomeres, and aging interventions ... 00:29:22

Evolution and progress in gene therapy ... 00:34:14

Barriers and ethics of gene therapy for rare diseases and children ... 00:36:53

Public perception and future accessibility ... 00:44:55

Affordability, scaling, and redosing gene therapies ... 00:55:00

Practical longevity habits and hormones ... 01:03:54

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Episode # 72: Harness the Power of Ice Baths to Rewire Your Brain and Heal Chronic and Acute Conditions

Episode # 72: Harness the Power of Ice Baths to Rewire Your Brain and Heal Chronic and Acute Conditions

My guest this week is Adrienne Jezick, Co-Founder Morozko Forge, Master Deliberate Cold Exposure (DCE) Guide. In this episode, Adrienne shares an all-too-familiar story of a major battle with autoimmunity to the point where she thought she was dying. Low and behold, she tried one natural therapy for autoimmunity after another until she noticed that ice baths, or deliberate cold exposure therapy, made the biggest impact. While an anti-inflammatory diet was also helpful, ice bath’s opened her eyes to a totally new world of healing autoimmunity naturally. Ice baths have the power to heal chronic and acute conditions and can be a complementary therapy for many other diseases. We encourage you to comb through the clinical research out there.  Perhaps one of the biggest deterrents for deliberate cold exposure is the fear of discomfort. That’s normal. Adrienne speaks with us today with full confidence that we can, with the right guidance, be someone who tolerates and benefits from ice baths.  Today’s episode will help you understand how to prepare for deliberate cold exposure, how long to stay in an ice bath, who should NOT try ice baths, what kind of breathwork is helpful for ice baths, contrast therapy, and how often you should do ice baths. And of course, what to do if you don’t have access to a place that has ice baths. Learn more about deliberate cold exposure (DCE) at https://www.morozkoforge.com or if you would like to be put on the waiting list for new training in 2022 then shoot Adrienne an email at info@morozkoforge.com. Sponsor Info:  Oxford HealthSpan brings us Primeadine, the best formulated Spermidine supplement on the market!  What makes it stand out – it includes Spermine & Putrescine two other Polyamines that work hand in hand with Spermidine PLUS FOS, a prebiotic to feed the bacteria in your gut that make Spermidine!  I take Spermidine daily as do my family and my clients – it has become a solid member of my “foundation stack”.  Research has shown that Spermidine upregulates autophagy, helps the immune system to rejuvenate and it protects DNA – visible benefits experienced by myself and my clients include better sleep, hair, skin and nails!   Sponsor offer: If you haven’t tried it yet go to Primeadine.com and use promo code BIONAT15 to save 15% at https://oxfordhealthspan.com/products/best-spermidine-supplement Episode Timestamps: [4:00] How Adrienne got where she is today… [9:00] Elimination diet and low inflammation food… [10:35] Discovering deliberate cold exposure (DCE)... [14:35] Hormetic stress vs an overwhelming stress to the body… [25:00] Breathwork, is there a preferred method of breathing for ice baths such as Wim Hoff? How do you get yourself into a calm state?.. [32:20] Is more time in the water better with cold therapy?.. [34:44] What is the value of other cold therapies such as ice showers and cryotherapy?.. [43:45] How long should you stay in the cold? Is there an ideal amount of time? [45:30] Is contrast therapy good for you?  [49:48] How many times a week should you do DCE for it to be effective?.. [52:16] What are the contraindications for DCE?.. [56:10] Raynaud's syndrome and cold exposure… [58:42] Cortisol issues and cold exposure… [62:11] How long did it take Adrienne to heal with cold therapy?.. [66:18] What is special about morozko forge ice baths?.. FOLLOW NAT Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult

7 Joulu 20211h 12min

Episode # 71: How to Boost the Effects of Anti-Aging Skincare and Light Therapy

Episode # 71: How to Boost the Effects of Anti-Aging Skincare and Light Therapy

My guest this week is Amitay Eshel, the co-founder, and CEO of Young Goose, the biohacking skincare brand. After serving in leading roles in Israel's special forces community, he has held executive roles in the health, wellness, and beauty industry for over a decade.  Young Goose embodies his two passions, performance optimization, and skin health, with products that boost the functions of natural rejuvenation processes in the skin. We're discussing anti-aging, biohacking for the skin and whole body, and red light therapy.  Guest Offer: Save 20% on your purchase of Young Goose SkinCare:  http://bit.ly/YOUNGGOOSE20 Code: SUPERHUMAN20 Follow Amitay https://www.instagram.com/young_goose_skincare https://www.younggoose.com/   Sponsor: Thanks to our Episode Sponsor BiOptimizers. BiOptimizers make the only full-spectrum and most bioavailable Magnesium Supplement on the market called Magnesium Breakthrough – I use it every day and every night for brain benefits, to optimize my sleep, and much more. This month is also when they are offering huge discounts and free products on all qualifying orders! Just use my exclusive link: www.magnesiumbreakthrough.com/bionat and use discount code "bionat" to stock up and SAVE! That's www.magnesiumbreakthrough.com/bionat with promo code “bionat”   Show Notes: [04:30] How do you go from Green Beret to Red Light Therapy to Skincare line? .. [11:00] Can you look younger without optimizing your overall health?.. [19:15] Light therapy for anti-aging, longevity, medical purposes and more… [32:25] Red light masks for anti-aging… [37:00] Can red light affect the infrastructure underneath the skin?.. [41:05] Red light therapy for the brain and gut… [49:45] Red light for hair growth… [56:45] Let’s talk about skincare… [62:15] NAD for health and skin… [73:40] Talking more about ingredients.. Chamomile to downregulate CD38.. Using fermented resveratrol, a polyphenol, and antioxidant. Ghk-cu for glycation and more… [79:30] Should all GHK-cu products be blue to be effective?.. [81:34] How do you figure out what products you should and shouldn’t trust?.. [85:06] What results should we expect from skincare as far as a reversal of skin damage?.. [86:55] Damaging the skin in order to remodel your skin.. Is there a limit to the number of procedures you can do for improvement?.. [93:03] What is in the face mask that Amitay gave Nathalie?..

30 Marras 20211h 39min

Episode #70: How an Endocrinologist Uses Peptides and Why Peptides Might be Banned by the FDA

Episode #70: How an Endocrinologist Uses Peptides and Why Peptides Might be Banned by the FDA

My guest this week is Dr. Edwin Lee Co-Founder of Clinical Peptide Society. In this episode, Dr. Edwin Lee and I discuss peptides, his book, and the many ways to heal the body without surgery. We also discuss stem cells, growth hormone secretagogues, and his passion project saving peptides from being taken away by the FDA. You can learn more about that here. Thank you to our sponsor Oxford HealthSpan. Primeadine is the best formulated Spermidine supplement on the market!  What makes it stand out – it includes Spermine & Putrescine two other Polyamines that work hand in hand with Spermidine PLUS FOS, a prebiotic to feed the bacteria in your gut that make Spermidine!  I take Spermidine daily as do my family and my clients – it has become a solid member of my “foundation stack”.  Research has shown that Spermidine upregulates autophagy, helps the immune system to rejuvenate and it protects DNA – visible benefits experienced by myself and my clients include better sleep, hair, skin, and nails!   Sponsor offer: If you haven’t tried it yet go to Primeadine.com and use promo code BIONAT15 to save 15% at https://oxfordhealthspan.com/products/best-spermidine-supplement Dr. Lee Bio:Dr. Edwin Lee is an endocrinologist, author, and international speaker. Dr. Lee founded the Institute for Hormonal Balance, Orlando, FL in 2008, is board-certified in Internal Medicine, Endocrinology, Diabetes, and Metabolism, and has completed special training in Regenerative and Functional Medicine.  He is a graduate of the Medical College of Pennsylvania and finished his fellowships of Critical Care Medicine and Endocrinology, Diabetes and Metabolism at the University of Pittsburgh. Follow Dr. Edwin Lee Save Peptides Website Peptide Study   Episode Timestamps: [05:20] How Dr.Lee got to where he is now… [10:49] Turning a patient's life around with peptides, exosomes and stem cells… [13:55] The difference between stem cells and exosomes… [20:35] Kisspeptin-10, does it actually help with testosterone? [23:50] Studies on knee pain treated with BPC-157… [41:30] Bioregulator peptides for prostate issues… [43:52] Growth hormone secretagogues: do they work, how do you monitor them, ect… [47:00] Are you a mouth breather?.. [50:41] Study on regeneration of the thymus gland using DHEA, metformin and growth hormone… [54:14] Do you see people whose bodies do not like secretagogues?.. [56:30] Thoughts on senolytics? What are the best senolytics… [67:45] How to save peptides and why does the FDA want to take them away?..   Follow Nat: Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult

23 Marras 20211h 17min

Episode # 69: The Best Way To Use Hyperbaric Oxygen Therapy For Chronic and Acute Conditions

Episode # 69: The Best Way To Use Hyperbaric Oxygen Therapy For Chronic and Acute Conditions

My guest this week is Dr. Scott Sherr of Integrative Hyperbaric Oxygen Therapy (HBOT). In this episode, Dr. Scott and I discuss Hyperbaric Oxygen Therapy, the many applications for it, and what to use in conjunction with HBOT for the best success. HBOT can be used for acute and chronic conditions however it should be done with someone who is very experienced in the field because it can have negative effects if the individual isn’t yet ready for that type of therapy.  HBOT is a treatment that utilizes two things: air/oxygen and pressure. These two factors can be particularly powerful in helping one’s body heal and regenerate.  Learn more about Hyperbaric Oxygen Therapy at hbot.plus/integrativehbot.   Dr. Scott Sherr is a Board Certified Internal Medicine Physician Certified in Hyperbaric Oxygen Therapy (HBOT) and Health Optimization Medicine (HOMe). He graduated Summa Cum Laude from UCLA as an undergraduate and Magna Cum Laude with Alpha Omega Alpha distinction from the University of Maryland Medical School in Baltimore.  Dr. Scott is one of the few HBOT providers in the country that creates personalized treatment plans for patients that include Health Optimization Medicine as its foundation, cutting edge & dynamic HBOT protocols as well as adjunctive technologies, practices, and practitioners. He consults, educates, and advocates for patients worldwide virtually through his website, www.integrativehbot.com.   His formal titles include Cofounder of Hbot Plus, COO of Health Optimization Medicine (a nonprofit education company) the USA, COO of Smarter Not Harder, Medical Advisor to the One Hit Away Foundation, and Hospitalist at Sequoia Hospital in Redwood City, CA.  Dr. Scott has consulted with clinics and wellness projects around the world including Upgraded Labs Lab (LA), Remedy Place (LA), LMS Wellness (London), and others. Follow Dr.Scott: https://hbot.plus/integrativehbot https://www.instagram.com/drscottsherr/?hl=en Episode Timestamps: [04:50] Dr.Scott’s story of how he got started on the path he is on… [11:40] Hyperbaric therapy for chronic health conditions vs acute conditions… [15:20] How hyperbaric therapy works… [20:45] Reactive oxygen species (ROS) and HBOT… [25:00] For people that do not make enough of their own glutathione and antioxidants is it helpful to replace those through supplementation?.. [27:45] Different types of chambers and pressures for different conditions [40:05] Molecular hydrogen in combination with HBOT?.. [49:50] What is the best way to use HBOT?.. [57:17] BPC-157 Stacked with HBOT for optimization?..   Follow Nat: Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult Thanks to our Episode Sponsor BiOptimizers. BiOptimizers make the only full-spectrum and most bioavailable Magnesium Supplement on the market called Magnesium Breakthrough – Iuse it every day and every night for brain benefits, to optimize my sleep, and much more. This month is also when they are offering huge discounts and free products on all qualifying orders! Just use my exclusive link: www.magnesiumbreakthrough.com/bionat and use discount code bionat to stock up and SAVE! BioOptimizers is launching their biggest sale of the entire year with a discount and bonus gifts. Visit www.magnesiumbreakthrough.com/bionat and use promo code bionat at checkout.  Sponsor offer: go to www.magnesiumbreakthrough.com/bionat and use code bionat for 10% off!

16 Marras 20211h 3min

Episode #68: Affordable Live Cell Banking with Acorn Biolabs

Episode #68: Affordable Live Cell Banking with Acorn Biolabs

My guest this week is Dr. Drew Taylor, co-founder, and CEO of Acorn Biolabs. In this episode, Dr. Taylor and I discuss live-cell banking, current applications for such cells, and future applications such as anti-aging, organ regeneration, and more. Acorn Biolans is an economical way for people to have access to their live cells. If you can afford Netflix, you can afford to bank your cells with Acorn Biolabs.  Learn more about Acorn Biolabs at https://landing.acorn.me/nat/  and receive three FREE months of cell banking on them! Thank you to Oxford Health for sponsoring this episode! Oxford HealthSpan brings us Primeadine, the best formulated Spermidine supplement on the market!  What makes it stand out – it includes Spermine & Putrescine two other Polyamines that work hand in hand with Spermidine PLUS FOS, a prebiotic to feed the bacteria in your gut that make Spermidine!  I take Spermidine daily as do my family and my clients – it has become a solid member of my “foundation stack”.  Research has shown that Spermidine upregulates autophagy, helps the immune system to rejuvenate and it protects DNA – visible benefits experienced by myself and my clients include better sleep, hair, skin, and nails!   Sponsor offer: If you haven’t tried it yet go to Primeadine.com and use promo code BIONAT15 to save 15% at https://oxfordhealthspan.com/products/best-spermidine-supplement Dr. Drew Taylor is Co-Founder and Chief Executive Officer at Acorn Biolabs.  Biologist and former professional athlete, Drew has charted his path across molecular cell biology, science and baseball with steadfast passion over his career.   Follow Drew Taylor at https://www.acorn.me/ https://www.facebook.com/acornbiolabs/ https://www.instagram.com/acornbiolabs/ https://www.linkedin.com/company/acornbiolabs/ [04:05] Dr. Taylor opens up about his life and how he got to where he is today… [07:55] What is tissue engineering?.. [13:09] After Dr. Taylor got his PHD what led him to this slightly different path?.. [27:40] How do you capture healthy cells and make sure you have them as a resource?.. [30:17] Cell banking from hair follicles?.. [36:50] When is the best time to bank your cells?.. [41:12] What exactly does Acorn Biolabs do? How do you know your cells are safe and secure?.. [43:40] What technologies are currently available for banked cells? What does the timeline look like for when different uses will be available? [53:00] Regenerating organs using stem cells.. [59:00] Is it possible to use a family member's banked cells?.. [62:30] What is the age of the youngest and oldest clients at Acorn Biolabs?.. [64:46] Who can access Acorn Biolabs services financially and location-wise?..

9 Marras 20211h 11min

Episode 67: You Do Not Have a Prozac Deficiency

Episode 67: You Do Not Have a Prozac Deficiency

My guest this week is Suzanne F. Turner, MD of Vine Medical. In this episode, Dr. Turner and I discuss why the common treatments for depression are not always the needed treatments for depression. Depression can be rooted in SO many different health issues that are treatable which is why jumping straight to Prozac and other antidepressants is premature. We discuss treating depression with nutrition, hormone therapy, peptides, eliminating certain medications, addressing trauma, and so much more. This is not to say that antidepressants aren’t needed at all. They can be helpful for some people however it is more important to treat the potential root causes of depression first, if more support is needed, then antidepressants can be warranted.   Learn more about Dr. Turner at Vine Medical Associates here. BiOptimizers is launching their biggest sale of the entire year with a discount and bonus gifts. Visit www.magnesiumbreakthrough.com/bionat and use promo code BIONAT at checkout. Dr. Turner is a physician/teacher/speaker/urban farmer/salsero/powerlifter/wife/bonus mom/ and "Birdie" practicing human performance and longevity medicine in Atlanta, GA. She is a recognized expert in the field of cellular medicine and the use of peptides and hormones. She has served on the faculty of Emory University, A4M, SSRP, ACAM, and BioTE and has been a featured guest on many podcasts. Follow Suzanne F Turner, MD Website Instagram LinkedIn YouTube EPISODE TAKEAWAYS [02:47] What made Dr. Turner choose the topic of depression for this episode?.. [06:30] What are some of the causes that can drive depression?.. [10:30] Your gut microbiome and how it affects mood.. [14:30] Hormones and depression… [20:40] The underperforming thyroid and depression… [26:55] What do lyne, mold and CIRS have in common that causes depression?.. [32:00] PE 3228; the bpeptide for depression? What about using semax and selank?.. [40:05] Anti-aging therapies for depression such as liraglutide, semaglutide, CJC and ipamorelin… [43:00] How can spermidine and butyrate help with depression?.. [47:00] Is depression a lack of fuel? Can something like ketone esters help depression?.. [50:10] Molecular hydrogen, a miracle selective antioxidant… [52:23] Oxytocin for repairing hippocampal function… FOLLOW NAT Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult   LINKAGE https://vinemedical.com/ https://www.instagram.com/drsturner/ https://www.linkedin.com/company/dr-s/ YouTube.com/dr-s-cellular-medicine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868755/ https://academic.oup.com/edrv/article/41/2/121/5658523 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457402/

2 Marras 20211h 1min

Episode #66 Inhale, Drink, and Topically Apply Your Way to Better Health with Brown's Gas

Episode #66 Inhale, Drink, and Topically Apply Your Way to Better Health with Brown's Gas

My guest this week is George Wiseman. In this episode, George and I discuss Brown’s gas and the many applications Brown’s Gas can be used for like inflammation, arthritis pain, viral infections, Parkinson's, overall immune strength, virtually any skin issues, radiation recovery, interrupting and preventing a cytokine storm, and so much more.  Learn more about Brown’s gas and the Aquacure at https://eagle-research.com/ and you can use Promo Code: Vitality to save 10% For more info & studies:  See Brown’s Gas testimonials / studies / etc. here: http://eagle-research.life http://www.molecularhydrogeninstitute.com/ About: George Wiseman began researching Brown’s Gas in 1986 and has become a world-renowned expert. While Brown’s Gas has unique properties with many practical uses, it’s also had its fair share of people promoting myth applications. With his research and development, he has dispelled the myths with scientific evidence and learned to design machines optimized for a variety of useful applications. Episode Takeaways [09:50] How George got started… [16:57] How much Brown's gas can you safely breathe?.. [19:50] Brown's gas for heart murmurs, tinnitus, and psoriasis?.. [23:00] Studies on molecular hydrogen by Dr. Tyler LeBaron (the hydrogen man)… [24:55] Do we need electrons in our water?.. [30:21] What makes molecular hydrogen different from other antioxidants?.. [34:45] Hydrogen for scars?.. [37:40] How long does it take to see positive results from hydrogen gas?.. [41:15] Studies on immune system modulation of viruses with Brown’s Gas machines… [50:33] Other ways that Brown’s Gas supports immunity… [53:50] Inflammation and how hydrogen affects that… [55:59] Studies on using Brown’s Gas for Parkinson’s disease… [57:15] Are hydrogen and Brown’s Gas radioactive protective?..   Follow Nat Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult Sponsor Info: Oxford HealthSpan brings us Primeadine, the best formulated Spermidine supplement on the market!  What makes it stand out – it includes Spermine & Putrescine two other Polyamines that work hand in hand with Spermidine PLUS FOS, a prebiotic to feed the bacteria in your gut that make Spermidine!  I take Spermidine daily as do my family and my clients – it has become a solid member of my “foundation stack”.  Research has shown that Spermidine upregulates autophagy, helps the immune system to rejuvenate and it protects DNA – visible benefits experienced by myself and my clients include better sleep, hair, skin and nails!   Sponsor offer: If you haven’t tried it yet go to Primeadine.com and use promo code BIONAT15 to save 15% at https://oxfordhealthspan.com/products/best-spermidine-supplement

26 Loka 20211h 7min

Episode #65: The Best Sleep Strategies You Might Not Have Tried Yet

Episode #65: The Best Sleep Strategies You Might Not Have Tried Yet

My guest this week is Molly McGlockin the creator of sleepisaskill.com In this episode, Molly and I discuss everything sleep! We talk about how sleep is a learned skill and the things we can do to hone in on that skill. Learn more about Sleep is a Skill at https://www.sleepisaskill.com/ [8:40] What got Mollie into being the sleep guru she is today?.. [16:50] How to overcome sleep anxiety and how the program works… [24:58] Looking at the “why” of sleep. Why is sleep important? Why did I make certain decisions?.. [29:00] Focusing on the biggest things that impact sleep such as circadian rhythm and work your way down to the easier things… [30:15] Focus on what you can do during the day to help with sleep, such as get more morning sunlight… [36:13] Sunglasses are not your friend… [40:48] Is camping the cure for insomnia?.. [41:50] Genetics and insomnia… [48:05] Is melatonin the key to good sleep?  [49:40] Napping, is it beneficial or detrimental?.. [57:00] Food, fasting and sleep… [62:05] The importance of being able to track sleep with a device such as the Oura ring… [72:42] Mollie’s favorite sleep supplements… [78:23] Mollies’s top three sleep tips…   Follow Nat Facebook Facebook Group  Instagram Work with Nat: Book Your 20 MInute Optimization Consult   Mollie McGlocklin is the creator of Sleep Is A Skill and the host of The Sleep Is A Skill Podcast. Sleep Is A Skill is a company that optimizes people’s sleep through a unique blend of technology, accountability, and behavioral change. After navigating insomnia while traveling internationally, she created what she couldn’t find - a place to go to learn the skill set of sleep. With a background in psychology and behavioral change from The Nonverbal Group, she became fascinated with chronobiology and its practical application to sleep and our overall experience of life. Knowing the difference between a life with sleep and without, she’s now dedicated her life to sharing the forgotten skill set of sleep. Follow Molly at https://www.sleepisaskill.com/ https://www.instagram.com/molliemcglocklin/ https://www.facebook.com/sleepisaskill/ https://www.linkedin.com/in/mollie-mcglocklin-sleep-is-a-skill-82531825/

19 Loka 20211h 25min

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