#517: Agentic Al Programming with Python

#517: Agentic Al Programming with Python

Agentic AI programming is what happens when coding assistants stop acting like autocomplete and start collaborating on real work. In this episode, we cut through the hype and incentives to define “agentic,” then get hands-on with how tools like Cursor, Claude Code, and LangChain actually behave inside an established codebase. Our guest, Matt Makai, now VP of Developer Relations at DigitalOcean, creator of Full Stack Python and Plushcap, shares hard-won tactics. We unpack what breaks, from brittle “generate a bunch of tests” requests to agents amplifying technical debt and uneven design patterns. Plus, we also discuss a sane git workflow for AI-sized diffs. You’ll hear practical Claude tips, why developers write more bugs when typing less, and where open source agents are headed. Hint: The destination is humans as editors of systems, not just typists of code.

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#550: AI Contributions and Maintainer Load in Open Source

#550: AI Contributions and Maintainer Load in Open Source

You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your open source project. Thirteen thousand lines added. No issue filed first. No discussion. Just "here, please rev...

30 Touko 1h 2min

#549: Great Docs

#549: Great Docs

Your documentation has two audiences now - humans reading the rendered HTML, and AI agents trying to make sense of your library. Rich Iannone and Michael Chow from Posit are back on Talk Python with a...

25 Touko 1h 7min

#548: Event Sourcing Design Pattern

#548: Event Sourcing Design Pattern

What if your database worked more like Git? Every change captured as an immutable event you can replay, instead of a single mutating row that quietly forgets its own history. That's event sourcing, an...

11 Touko 1h 8min

#547: Parallel Python at Anyscale with Ray

#547: Parallel Python at Anyscale with Ray

When OpenAI trained GPT-3, they didn't roll their own orchestration layer. They used Ray, an open source Python framework born out of the same Berkeley research lab lineage that gave us Apache Spark. ...

6 Touko 59min

#546: Self hosting apps for Python people

#546: Self hosting apps for Python people

The cloud is convenient until it isn't. You upload your photos, sync your contacts, click through the cookie banners. Then prices go up again or you read about a family that lost their entire Google a...

27 Huhti 1h 3min

#545: OWASP Top 10 (2025 List) for Python Devs

#545: OWASP Top 10 (2025 List) for Python Devs

The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Tanya Janca is back on Talk Python to walk us through every si...

16 Huhti 1h 6min

#544: Wheel Next + Packaging PEPs

#544: Wheel Next + Packaging PEPs

When you pip install a package with compiled code, the wheel you get is built for CPU features from 2009. Want newer optimizations like AVX2? Your installer has no way to ask for them. GPU support? Yo...

10 Huhti 1h 11min

#543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate

#543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate

When you type a question into ChatGPT, the model only has what you typed to work with. But tools like Claude Code can plan, iterate, test, and recover from mistakes. They work more like we do. The dif...

1 Huhti 1h 3min