The Startup Powering The Data Behind AGI

The future of AI is physical. In this episode, Lukas Biewald talks to Nikolaus West, CEO of Rerun, about why the breakthrough required to get AI out of the lab and into the messy real world is blocked by poor data tooling. Nikolaus explains how Rerun solved this by adopting an Entity Component System (ECS), a data model built for games, to handle complex, multimodal, time-aware sensor data. This is the technology that makes solving previously impossible tasks, like flexible manipulation, suddenly feel "boring." Connect with us here: Nikolaus West: https://www.linkedin.com/in/nikolauswest/Rerun: https://www.linkedin.com/company/rerun-io/Lukas Biewald: https://www.linkedin.com/in/lbiewald/Weights & Biases: https://www.linkedin.com/company/wandb/

16 Joulu 1h

Is video AI a viable path toward AGI? Runway ML founder Cristóbal Valenzuela joins Lukas Biewald just after Gen 4.5 reached the #1 position on the Video Arena Leaderboard, according to community voting on Artificial Analysis. Lukas examines how a focused research team at Runway outpaced much larger organizations like Google and Meta in one of the most compute-intensive areas of machine learning.Cristóbal breaks down the architecture behind Gen 4.5 and explains the role of “taste” in model development. He details the engineering improvements in motion and camera control that solve long-standing issues like the restrictive “tripod look,” and shares why video models are starting to function as simulation engines with applications beyond media generation.Connect with us here:Cristóbal Valenzuela: https://www.linkedin.com/in/cvalenzuelabRunway: https://www.linkedin.com/company/runwayml/Lukas Biewald: https://www.linkedin.com/in/lbiewald/Weights & Biases: https://www.linkedin.com/company/wandb/

1 Joulu 14min

In this episode of Gradient Dissent, Lukas Biewald talks with Tuhin Srivastava, CEO and founder of Baseten, one of the fastest-growing companies in the AI inference ecosystem. Tuhin shares the real story behind Baseten’s rise and how the market finally aligned with the infrastructure they’d spent years building.They get into the core challenges of modern inference, including why dedicated deployments matter, how runtime and infrastructure bottlenecks stack up, and what makes serving large models fundamentally different from smaller ones.Tuhin also explains how vLLM, TensorRT-LLM, and SGLang differ in practice, what it takes to tune workloads for new chips like the B200, and why reliability becomes harder as systems scale. The conversation dives into company-building, from killing product lines to avoiding premature scaling while navigating a market that shifts every few weeks.Connect with us here: Tuhin Srivastva: https://www.linkedin.com/in/tuhin-srivastava/ Lukas Biewald: https://www.linkedin.com/in/lbiewald/Weights & Biases: https://www.linkedin.com/company/wandb/

18 Marras 59min

In this episode of Gradient Dissent, Lukas Biewald sits down with Arvind Jain, CEO and founder of Glean. They discuss Glean's evolution from solving enterprise search to building agentic AI tools that understand internal knowledge and workflows. Arvind shares how his early use of transformer models in 2019 laid the foundation for Glean’s success, well before the term "generative AI" was mainstream.They explore the technical and organizational challenges behind enterprise LLMs—including security, hallucination suppression—and when it makes sense to fine-tune models. Arvind also reflects on his previous startup Rubrik and explains how Glean’s AI platform aims to reshape how teams operate, from personalized agents to ever-fresh internal documentation.Follow Arvind Jain: https://x.com/jainarvindFollow Weights & Biases: https://x.com/weights_biasesTimestamps: [00:01:00] What Glean is and how it works [00:02:39] Starting Glean before the LLM boom [00:04:10] Using transformers early in enterprise search [00:06:48] Semantic search vs. generative answers [00:08:13] When to fine-tune vs. use out-of-box models [00:12:38] The value of small, purpose-trained models [00:13:04] Enterprise security and embedding risks[00:16:31] Lessons from Rubrik and starting Glean [00:19:31] The contrarian bet on enterprise search [00:22:57] Culture and lessons learned from Google [00:25:13] Everyone will have their own AI-powered "team" [00:28:43] Using AI to keep documentation evergreen [00:31:22] AI-generated churn and risk analysis [00:33:55] Measuring model improvement with golden sets[00:36:05] Suppressing hallucinations with citations [00:39:22] Agents that can ping humans for help [00:40:41] AI as a force multiplier, not a replacement [00:42:26] The enduring value of hard work

5 Elo 43min

In this episode of Gradient Dissent, Lukas Biewald talks with Jarek Kutylowski, CEO and founder of DeepL, an AI-powered translation company. Jarek shares DeepL’s journey from launching neural machine translation in 2017 to building custom data centers and how small teams can not only take on big players like Google Translate but win.They dive into what makes translation so difficult for AI, why high-quality translations still require human context, and how DeepL tailors models for enterprise use cases. They also discuss the evolution of speech translation, compute infrastructure, training on curated multilingual datasets, hallucinations in models, and why DeepL avoids fine-tuning for each individual customer. It’s a fascinating behind-the-scenes look at one of the most advanced real-world applications of deep learning.Timestamps: [00:00:00] Introducing Jarek and DeepL’s mission [00:01:46] Competing with Google Translate & LLMs [00:04:14] Pretraining vs. proprietary model strategy [00:06:47] Building GPU data centers in 2017 [00:08:09] The value of curated bilingual and monolingual data [00:09:30] How DeepL measures translation quality [00:12:27] Personalization and enterprise-specific tuning[00:14:04] Why translation demand is growing [00:16:16] ROI of incremental quality gains [00:18:20] The role of human translators in the future [00:22:48] Hallucinations in translation models [00:24:05] DeepL’s work on speech translation [00:28:22] The broader impact of global communication [00:30:32] Handling smaller languages and language pairs [00:32:25] Multi-language model consolidation [00:35:28] Engineering infrastructure for large-scale inference [00:39:23] Adapting to evolving LLM landscape & enterprise needs

8 Heinä 42min

In this episode of Gradient Dissent, Lukas Biewald sits down with Thomas Dohmke, CEO of GitHub, to talk about the future of software engineering in the age of AI. They discuss how GitHub Copilot was built, why agents are reshaping developer workflows, and what it takes to make tools that are not only powerful but also fun.Thomas shares his experience leading GitHub through its $7.5B acquisition by Microsoft, the unexpected ways it accelerated innovation, and why developer happiness is crucial to productivity. They explore what still makes human engineers irreplaceable and how the next generation of developers might grow up coding alongside AI.Follow Thomas Dohmke: https://www.linkedin.com/in/ashtom/Follow Weights & Biases:https://twitter.com/weights_biases https://www.linkedin.com/company/wandb

10 Kesä 1h 9min

In this episode of Gradient Dissent, Lukas Biewald talks with Martin Shkreli — the infamous "pharma bro" turned founder — about his path from hedge fund manager and pharma CEO to convicted felon and now software entrepreneur. Shkreli shares his side of the drug pricing controversy, reflects on his prison experience, and explains how he rebuilt his life and business after being "canceled."They dive deep into AI and drug discovery, where Shkreli delivers a strong critique of mainstream approaches. He also talks about his latest venture in finance software, building Godel Terminal “a Vim for traders", and why he thinks the AI hype cycle is just beginning. It's a wide-ranging and candid conversation with one of the most controversial figures in tech and biotech.Follow Martin Shkreli on TwitterGodel Terminal: https://godelterminal.com/Follow Weights & Biases on Twitterhttps://www.linkedin.com/company/wandb Join the Weights & Biases Discord Server:https://discord.gg/CkZKRNnaf3

20 Touko 1h 30min