Ep 108 Gout: Toetally fascinating

Ep 108 Gout: Toetally fascinating

Although today we tend to think about diseases in terms of signs and symptoms, tests and treatments, that hasn’t always been the case. For much of history, diseases carried with them a deeper meaning beyond the pathophysiological processes leading to their development. A diagnosis was as much about the identity and personality of an individual as it was about the disease itself, and this was especially the case for the topic of today’s episode: gout. But before we get into the tangled history of this “monarch among maladies”, we first break down its biology and possible evolutionary origins. Once we have a solid understanding of this crystalline illness, we turn our attention to the changing perceptions of gout over time and why gout was once a welcomed diagnosis, in sharp contrast with so many other diseases. Finally, we take stock of gout around the world today, no easy feat. Tune in for a fascinating deep dive into this incredibly common but often overlooked illness.

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Jaksot(282)

Ep 187 Hypothermia Part 2: How it helps

Ep 187 Hypothermia Part 2: How it helps

Last week, we took you through all the ways that cold can harm us and the harrowing history of humans perishing at its icy hands. Ending the story there would be skipping over the parts where cold get...

9 Syys 20251h 5min

Ep 186 Hypothermia Part 1: How it hurts

Ep 186 Hypothermia Part 1: How it hurts

For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dw...

2 Syys 202557min

Special Episode: Lina Zeldovich & The Living Medicine

Special Episode: Lina Zeldovich & The Living Medicine

The development of antibiotics was one of the greatest turning points in the history of medicine. Bacterial infections that were once death sentences were cured within a matter of days after administr...

26 Elo 202551min

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the f...

19 Elo 20251h 14min

Ep 184 The Gallbladder: Humor us

Ep 184 The Gallbladder: Humor us

For most of us, there probably hasn’t been a good reason for you to think about your gallbladder. Ever. Much of the time, it sits there, silently storing, concentrating, and, when needed, churning out...

12 Elo 20251h 22min

Special Episode: Carl Zimmer & Airborne

Special Episode: Carl Zimmer & Airborne

In the first years of the COVID pandemic, a debate raged: was the virus transmitted via respiratory droplets, or was it airborne? For some, this distinction seemed overly technical, pedantic even. But...

5 Elo 202549min

Ep 183 SSRIs Part 2: Action

Ep 183 SSRIs Part 2: Action

Last week, we took you on a journey of discovery and innovation, and this week we’re gonna tell you how the heck it all works. That means a deep dive into the nitty gritty of SSRIs, from what serotoni...

29 Heinä 20251h 10min

Ep 182 SSRIs Part 1: Origin

Ep 182 SSRIs Part 1: Origin

Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunde...

22 Heinä 20251h 2min

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