E129: Sam Altman plays chess with regulators, AI's "nuclear" potential, big pharma bundling & more

E129: Sam Altman plays chess with regulators, AI's "nuclear" potential, big pharma bundling & more

(0:00) Bestie intros!: Reddit Performance Reviews

(5:14) Quick AIS 2023 update

(6:27) AI Senate hearing: Sam Altman playing chess with regulators, open-source viability

(21:25) Regulatory capture angle, "preemptive regulation," how AI relates to nuclear, insider insights from the White House's AI summit

(43:33) Elon hires new Twitter CEO

(48:46) Lina Khan moves to block Amgen's $27.8B acquisition of Horizon Therapeutics

(1:02:30) Apple's AR goggles are reportedly being unveiled at WWDC in early June, platform shift potential, how it deviates from Apple's prior launch strategies

(1:07:45) Residential and commercial real estate headwinds

(1:15:29) Unrest in SF and NYC after two recent tragic incidents ended in death

(1:24:20) Soros political motivations for backing progressive DAs

Follow the besties:

https://twitter.com/chamath

https://linktr.ee/calacanis

https://twitter.com/DavidSacks

https://twitter.com/friedberg

Follow the pod:

https://twitter.com/theallinpod

https://linktr.ee/allinpodcast

Intro Music Credit:

https://rb.gy/tppkzl

https://twitter.com/yung_spielburg

Intro Video Credit:

https://twitter.com/TheZachEffect

Referenced in the show:

https://techcrunch.com/2023/05/18/psst-gary-marcus-is-happy-to-help-regulate-ai-on-behalf-of-the-u-s-government/

https://twitter.com/chamath/status/1658913074106236931

https://www.mosaicml.com/blog/mpt-7b

https://huggingface.co/spaces/HuggingFaceH4/open_llm_leaderboard

https://artificialintelligenceact.eu

https://futurism.com/the-byte/warren-buffett-ai-atom-bomb

https://www.cnbc.com/2023/05/12/nbcuniversal-ad-chief-yaccarino-resigns-as-sources-say-shes-in-talks-to-be-twitter-ceo.html

https://www.wsj.com/articles/ftc-poised-to-block-amgens-27-8-billion-deal-for-horizon-therapeutics-a9c1b499

https://www.ftc.gov/system/files/ftc_gov/pdf/2310037amgenhorizoncomplainttropi.pdf

https://www.benefitspro.com/2023/05/12/pbms-the-brokers-who-control-drug-prices-finally-get-washingtons-attention

https://sharegpt.com/c/O6OKM9D

https://www.wsj.com/articles/apple-mixed-reality-headset-9213ac1b

https://twitter.com/PalmerLuckey/status/1657828947877560323

https://twitter.com/DavidSacks/status/1658955195450286081

https://www.foxnews.com/us/witness-jordan-neely-chokehold-death-calls-daniel-penny-hero

https://www.reddit.com/r/nyc/comments/1njfls/try_to_stay_away_from_the_michael_jackson

https://en.wikipedia.org/wiki/1984_New_York_City_Subway_shooting

https://en.wikipedia.org/wiki/Guardian_Angels

https://www.messynessychic.com/2019/03/26/in-the-shadows-with-nycs-self-styled-guardian-angels

https://www.eviemagazine.com/post/media-falsely-representing-jordan-neely-10-year-old-photos-crucial-information

https://twitter.com/Jason/status/1655716240500080640

https://www.foxnews.com/politics/george-soros-son-visited-white-house-dozen-times-since-biden-took-office-records-show

Jaksot(350)

E104: FTX collapse with Coinbase CEO Brian Armstrong + election results, macro update & more

E104: FTX collapse with Coinbase CEO Brian Armstrong + election results, macro update & more

(0:00) New bestie game show! (6:20) Election recap: Red wave falls flat, Republican party flips from Trump to DeSantis, a rebuke of extremism (20:47) Coinbase CEO Brian Armstrong joins to break down t...

12 Marras 20221h 25min

E103: Tech layoffs surge, big tech freezes hiring, optimizing for profits, election preview & more

E103: Tech layoffs surge, big tech freezes hiring, optimizing for profits, election preview & more

(0:00) Jason's new brand deal (1:18) Bestie updates (9:12) "Ligma/Johnson" blunder outside of Twitter HQ (15:38) Surge of tech layoffs at Twitter, Stripe, Lyft, Opendoor, Chime and others; preparing f...

5 Marras 20221h 28min

E102: Elon closes Twitter deal, $META uncertainty, Zuck's historic bet, big tech decline & more

E102: Elon closes Twitter deal, $META uncertainty, Zuck's historic bet, big tech decline & more

(0:00) Sacks is back! (1:01) Sacks recaps his week off (3:13) Elon finalizes Twitter deal, immediate content moderation decisions, platform potential (31:19) Meta's historic bet on VR and stock price ...

29 Loka 20221h 36min

E101: Ye acquires Parler, Snap drops 30%, macro outlook, VC metrics, valuing stocks & more

E101: Ye acquires Parler, Snap drops 30%, macro outlook, VC metrics, valuing stocks & more

(0:00) Bestie intros: Brad Gerstner joins in place of Sacks, and brigadoons! (2:02) Ye's current situation and acquisition of Parler (14:17) Snap drops ~30%, corporate misgovernance, super-voting shar...

22 Loka 20221h 41min

E100: Reflecting on the first 100 shows, fan questions, nuclear threat, markets, Amazon & more

E100: Reflecting on the first 100 shows, fan questions, nuclear threat, markets, Amazon & more

(0:00) Bestie intros are back! (6:35) Reflecting on the first 100 episodes and what makes the show special (29:12) Fan questions: Building in a downturn, how to be successful in tech, importance of un...

14 Loka 20221h 29min

E99: Cheating scandals, Twitter updates, rapid AI advancements, Biden's pardon, Section 230 & more

E99: Cheating scandals, Twitter updates, rapid AI advancements, Biden's pardon, Section 230 & more

0:00 Bestie intros! 1:34 Breaking down major cheating scandals: chess, poker, fishing 16:13 Twitter deal updates 30:05 AI making rapid advancements: Tesla AI Day, Meta's text-to-video tool, where this...

7 Loka 20221h 25min

E98: Big tech starts making cuts, Fed incompetency, global debt, Russia/Ukraine & more

E98: Big tech starts making cuts, Fed incompetency, global debt, Russia/Ukraine & more

0:00 Bestie intros! 1:36 Big tech starts making cuts, plus what this means for the broader economy and startups 31:09 Global debt numbers, Fed incompetency 54:06 RIP Coolio 1:00:30 Russia / Ukraine up...

1 Loka 20221h 19min

E97: SPAC updates, public/private market overview, Putin's end game & more

E97: SPAC updates, public/private market overview, Putin's end game & more

0:00 Bestie intros! 1:03 SPAC updates, state of the public/private markets 20:26 US VCs have $290B in dry powder and raised a record amount in H1 2022, is the market nearing a bottom? 31:14 Risks of b...

23 Syys 20221h 24min

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