Oct 03 2025 This Week in Cardiology

Oct 03 2025 This Week in Cardiology

Two great stories of translation science leading to beneficial drugs in terrible diseases of the heart and the Sisyphean task of predicting the need for pacing after TAVI are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I Sotatercept

  • HYPERION Trial https://www.nejm.org/doi/10.1056/NEJMoa2508170
  • ZENITH Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2415160
  • Evidence report on treatment for PAH https://icer.org/news-insights/press-releases/icer-publishes-final-evidence-report-on-treatment-for-pulmonary-arterial-hypertension/
  • PAH Sotatercept Editorial https://www.nejm.org/doi/full/10.1056/NEJMe2503944

II Acoramidis and ATTR Cardiomyopathy

  • ATTRIBUTE-CM Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2305434?logout=true
  • ATTRIBUTE-CM Analysis - Substudy https://www.jacc.org/doi/10.1016/j.jacc.2025.09.013
  • Tafamadis Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1805689

III Pacing After TAVI

  • Prophylactic pacemaker after TAVI https://www.jacc.org/doi/10.1016/j.jacep.2025.07.028
  • PROMOTE study https://doi.org/10.1016/j.hrthm.2024.12.019
  • Evaluation of ESC criteria on RBBB patients undergoing TAVI https://doi.org/10.1016/j.hrthm.2024.11.030
  • Editorial on Heart Rhythm journal papers https://www.heartrhythmjournal.com/article/S1547-5271(25)00114-6/abstract

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact news@medscape.net

Jaksot(396)

Jan 16, 2026 This Week in Cardiology

Jan 16, 2026 This Week in Cardiology

Some great listener feedback, one of the best studies of the year in atrial fibrillation and heart failure, imaging to exclude left atrial thrombus, and a truly amazing first cardiac procedure are the...

16 Tammi 30min

Jan 09 2026 This Week in Cardiology

Jan 09 2026 This Week in Cardiology

The limits of knowing coronary artery disease anatomy, fish oil and AF risk, a new drug for PSVT, and maybe I was wrong about a drug for AF conversion (the RAFF4 trial). These are the topics John Mand...

9 Tammi 28min

Dec 19 2025 This Week in Cardiology

Dec 19 2025 This Week in Cardiology

The MI paradox of risk scores, the CELEBRATE trial of a new subcutaneous glycoprotein IIb/IIIA inhibitor (with its funny endpoint), the SURPASS CVOT trial, and the bad story of andexanet alfa are the ...

19 Joulu 202535min

Dec 12 2025 This Week in Cardiology

Dec 12 2025 This Week in Cardiology

An elegant study in post-TAVI atrioventricular block, a PSA for my structural colleagues, revascularization in women, and a CTO PCI trial are the topics John Mandrola, MD, discusses in this week's pod...

12 Joulu 202527min

Dec 05 2025 This Week in Cardiology

Dec 05 2025 This Week in Cardiology

Less is more after PCI, the TARGET-FIRST trial, a negative blood pressure trial that is actually positive, aspirin vs OAC for bleeding, AEDs, and Factor XI is not dead yet are the topics discussed by ...

5 Joulu 202529min

Nov 21 2025 This Week in Cardiology

Nov 21 2025 This Week in Cardiology

Listener feedback, huge news in the world of carotid disease with the CREST-2 publication, prasugrel beats ticagrelor again, and a big coffee trial are the topics John Mandrola, MD, discusses in this ...

21 Marras 202529min

Nov 14 2025 This Week in Cardiology

Nov 14 2025 This Week in Cardiology

Listener feedback on the PISCES trial, AHA news (including a big PCSK9i trial), beta-blockers post MI, LAAC, and post-AF ablation OAC use are the topics John Mandrola, MD, discusses in this week's pod...

14 Marras 202536min

Nov 07, 2025 This Week in Cardiology

Nov 07, 2025 This Week in Cardiology

Listener feedback on non-culprit PCI in STEMI, a major cardiac result in patients on hemodialysis, news on GLP-1 agonists, a dubious stroke trial, and an AHA preview are the topics John Mandrola, MD, ...

7 Marras 202532min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
mielipaivakirja
rss-duodecim-lehti
rss-poliisin-mieli
utelias-mieli
radio-antro
docemilia
menologeja-tutkimusmatka-vaihdevuosiin
rss-metsa
rss-ylistys-elaimille
rss-sosiopodi