TWiV 819: How to stall a copy machine

TWiV 819: How to stall a copy machine

TWiV explains how remdesivir inhibits the SARS-CoV-2 RNA polymerase: the drug is incorporated into the growing RNA chain and causes synthesis to stall when the drug clashes with an amino acid in the active site.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode Weekly Picks

Kathy – Great Lakes Science Center, Cleveland
Rich How to Temporarily Disable Your Keyboard with a Keyboard Shortcut in Windows
Alan – How to Make a Slave and Other Essays by Jerald Walker
VincentA structure for deoxyribose nucleic acid

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Intro music is by Ronald Jenkees

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