Digital Twins: The End of Human Drug Testing for Biohackers  : 1342

Digital Twins: The End of Human Drug Testing for Biohackers : 1342

AI is transforming medicine at a speed never seen before. In this episode, you’ll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to create truly individualized medicine.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Dr. Derya Unutmaz is a world-renowned immunologist, systems biologist, and professor at The Jackson Laboratory. With more than 150 scientific papers, he’s a leading expert in immune system research and one of the first scientists to pioneer the concept of digital twins for biology. His groundbreaking work uses AI to model how immunity, metabolism, and aging interact—creating new possibilities for personalized medicine, disease prevention, and lifespan extension.


Host Dave Asprey and Dr. Unutmaz reveal how AGI will soon outperform doctors, accelerate functional medicine, and optimize human biology far beyond today’s standards. You’ll learn how the immune system drives inflammation and aging, how to re-engineer it for resilience, and why compounds like GLP-1 and metformin may add years to your life.


You’ll Learn:

• How digital twins will end human drug testing

• Why AGI could replace doctors and computer jobs within five years

• How AI models immune function, metabolism, and aging

• The role of mitochondria and inflammation in longevity

• How GLP-1 drugs and metformin extend lifespan

• What continuous biological monitoring means for health tracking

• How AI is transforming functional medicine and personalized care

• Why NAD and energy metabolism are key to human performance


They explore how artificial intelligence, biohacking, and systems biology intersect to create a smarter approach to health and longevity. You’ll also learn how understanding immune balance, metabolism, and mitochondrial function helps build resilience and extend your lifespan.


This is essential listening for anyone serious about biohacking, hacking human performance, and extending longevity through personalized medicine, functional biology, and cutting-edge AI innovation.


This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You’ll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: AI medicine, Digital twins, Functional medicine, Biohacking, Longevity, Immune system, Inflammation, Personalized medicine, GLP-1 therapy, Metformin, NAD boosters, Mitochondrial function, Metabolism, AGI, Clinical trials, Human performance, Aging research, Systems biology, Immunology, Smarter Not Harder


Thank you to our sponsors!


Resources:

• Keep up with Derya’s work: https://x.com/derya_?lang=en

• Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/

• Danger Coffee: https://dangercoffee.com/discount/dave15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

00:00 — Trailer

01:25 — Intro

02:26 — AI’s Role in Extending Lifespan

02:56 — Regulatory Frameworks and Medical Adoption

05:19 — Problems with the Immune System

08:19 — Chronic Fatigue and Long COVID Research

10:32 — Modern Testing and Multi-Omic Analysis

14:07 — Personal Longevity Strategy and Supplements

15:17 — Understanding Exhausted Cells

23:43 — Personalization in Medicine and AI Analysis

31:35 — Longevity Escape Velocity

36:13 — AI Doctors and Prescriptions

39:55 — Data Quality Concerns in AI Training

43:19 — The Future of Wearable Technology

45:50 — Revolutionizing Education with AI

49:04 — The Future of Higher Education

52:03 — Future of Work and AI Agents

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1437)

Podcast #30: Sweet Potato Power with Ashley Tudor

Podcast #30: Sweet Potato Power with Ashley Tudor

Ashley Tudor is a Design Strategist with the Spruce Street Institute where she works to create innovations in healthcare for doctors, patients and kids. She has worked with a wide range of Fortune 500 companies on a variety of projects including envisioning the future of cars, finding new ways for people to invest their money, designing ways to help food companies fight obesity, and coming up with new medical devices for primary care physicians. Ashley was named one of San Francisco’s Top Innovators in Health in 2010.Aside from her business exploits, Ashley is the author of Sweet Potato Power, a book aimed at promoting what she believes to be one of the healthiest and most high performance foods you can eat.  Ashley comes on Upgraded Self Radio to talk about how you can use the power of sweet potatoes to look, feel, and perform better. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Elo 20121h 12min

Podcast #29: How Real Food Improves Your Performance with Joel Salatin

Podcast #29: How Real Food Improves Your Performance with Joel Salatin

Joel F. Salatin is an American farmer, lecturer, and author whose books include Folks, This Ain't Normal, You Can Farm, and Salad Bar Beef. Salatin raises livestock using holistic methods of animal husbandry, free from harmful chemicals, on his Polyface Farm in Swoope, Virginia, in the Shenandoah Valley. Joel joins us today to talk about his unique farming methods, and why they improve both your health, and the health of the animals. Click here to subscribe to the podcast in iTunes. Click here to read the free transcript of this episode (coming soon). See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Kesä 20121h 20min

Podcast #28: Monitoring Your Brain with Chris Berka

Podcast #28: Monitoring Your Brain with Chris Berka

Chris Berka is the CEO and Co-Founder at Advanced Brain Monitoring (ABM). She has over 25 years experience managing clinical research and developing and commercializing new technologies. Co-inventor of nine patented and 11 patent-pending technologies, Ms. Berka is the principal investigator or co-investigator for grants & contracts awarded by the National Institutes of Health, DARPA, ONR and NSF that provided more than $22 million of research funds to ABM. Chris Berka comes on Upgraded Self Radio to talk about how you can use advanced brain monitoring technology to improve your mental and physical performance. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Touko 20121h 18min

Podcast #27: Minding My Mitochondria with Dr. Terry Wahls, MD

Podcast #27: Minding My Mitochondria with Dr. Terry Wahls, MD

16 Touko 20121h 8min

Podcast #26: Body By Science with Dr. Doug McGuff, MD

Podcast #26: Body By Science with Dr. Doug McGuff, MD

9 Touko 20121h 17min

Podcast #25: Wheat Belly with Dr. William Davis, MD

Podcast #25: Wheat Belly with Dr. William Davis, MD

2 Touko 20121h 9min

Podcast #24: Becoming Awesome with Julien Smith

Podcast #24: Becoming Awesome with Julien Smith

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Podcast #23: The Art of Less Doing with Ari Meisel

Podcast #23: The Art of Less Doing with Ari Meisel

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