Why Women’s Joints Are Failing 10x Faster : 1349

Why Women’s Joints Are Failing 10x Faster : 1349

Modern joint pain isn’t just wear and tear—it’s a systemic, metabolic disease that starts years before symptoms show. In this episode, you’ll learn how inflammation, mitochondria dysfunction, and immune imbalance trigger cartilage loss… and how to reverse it using targeted cytokine modulation, cellular regeneration, and smarter supplements for longevity and human performance.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey sits down with Kiran Krishnan, an expert microbiologist and advisor to Calroy Health Sciences. He’s the founder of Microbiome Labs—one of the most trusted microbiome-focused brands in functional medicine—and a formulator behind cutting-edge supplements like Arterosil and Vascanox. With over two decades of experience, Kiran has launched multiple health ventures, authored scientific textbook chapters, published clinical trials, and holds global patents in human health. He’s a leading authority on systemic inflammation, mitochondrial dysfunction, and gut-driven disease—and one of the few voices making complex biology accessible for real-world results.


He breaks down their new supplement Cartigenix HP, and how cytokines like IL-6 and TNF-alpha flip your cartilage cells from anabolic repair to catabolic destruction, how mitochondrial decline speeds up joint damage, and why most modern painkillers make your joints worse. You’ll learn how a specialized blend of boswellia and celery seed reprograms inflammation, why walking beats medication in clinical trials, and how fasting, nitric oxide, and gut health work together to optimize joint regeneration.


You’ll learn:

• How cartilage cells (chondrocytes) rely on mitochondria for tissue repair

• Why global cytokines like IL-6 and TNF-alpha drive joint degradation and brain fog

• How cartilage begins to break down in your teens—and what to do about it now

• The surprising clinical data on walking distance, inflammation markers, and recovery

• Why most supplements and NSAIDs fail—and what actually rebuilds joints

• How diet and leaky gut create 5-day inflammation spikes from a single fast-food meal

• The mitochondrial link between joint pain, cardiovascular risk, and depression

• Why perimenopausal women are at 10x higher risk for arthritis—and how to prevent it

• How to track your biological joint age using imaging and systemic inflammation labs


This is essential listening for anyone serious about biohacking, functional medicine, pain-free aging, and human performance. Whether you’re lifting heavy, walking daily, or just trying to stay mobile into old age, this episode gives you the science and tools to reverse joint degeneration and extend your healthspan.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: Joint cartilage regeneration, IL-6 inflammation suppression, TNF-alpha cytokine modulation, Chondrocyte mitochondrial repair, Catabolic to anabolic tissue shift, Osteoarthritis reversal, Rheumatoid arthritis inflammation, Mitochondria and collagen synthesis, Boswellia seratol extract, Celery seed COX inhibition, Matrix metalloproteinase (MMP) inhibition, Synovial fluid inflammation, Leaky gut and joint pain, Six-minute walk test improvement, Global cytokine markers, High sensitivity CRP reduction, ESR sedimentation rate, Uric acid crystal formation, Post-prandial glucose walking, Cartilage MRI biomarkers, Functional medicine joint support, Fasted repair stacking, Vasodilation and nitric oxide, Anti-inflammatory supplement stacking, NF-kB pathway reduction, Joint space biological age, Microvascular circulation and cartilage, Caloric load and cytokine spike, Perimenopause and arthritis risk, Joint tissue anabolic activation


**Get an exclusive discount for podcast listeners at calroy.com/dave : https://calroy.com/product/cartigenix-hp/?lp=dave **


Thank you to our sponsors!

-BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off.

-BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order.

-Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

-Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order.


Resources:

• Danger Coffee: https://dangercoffee.com/discount/dave15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 — Trailer

1:25 — Introduction

2:01 — Why Modern Medicine Fails at Joint Pain

3:07 — Painkillers That Accelerate Joint Damage

7:35 — Rheumatoid vs. Osteoarthritis Explained

8:54 — Cytokines That Destroy Cartilage

12:10 — Arthritis Begins in Your Teens

15:35 — 75% Pain Reduction in 7 Days

18:35 — The Science Behind Boswellia & Celery Seed

24:10 — Six-Minute Walk Test Results

25:45 — The $200/Month Painkiller Trap

28:53 — Proof Cartilage Can Regrow

31:01 — Mitochondria and Joint Repair

32:29 — Inflammation Links to Heart Disease

35:52 — Why Glucosamine Doesn’t Work

37:07 — Silent Arthritis in 90% of Adults

40:44 — Why Women Face Higher Joint Risk After 40

45:52 — Food as the #1 Inflammation Trigger

47:23 — Fasting & Cartogenics Stack for Repair

50:27 — Movement Snacks and Efficient Training

55:54 — Why Joints Heal Slower Than Muscles

57:48 — Dave’s Stack and Final Takeaways

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1415)

Dana Walsh & Brent Martin: Lyme Less, Live More - #255

Dana Walsh & Brent Martin: Lyme Less, Live More - #255

Dana and Brent come on Bulletproof Radio today to share their personal experience with Lyme disease and toxic mold exposure, as well as their suggestions on how you can cope with chronic illness. Dana Walsh, featured in the Lyme Documentary UNDER OUR SKIN, and Brent Martin are founders of Lyme Less Live More, identified a giant gap while recovering from Lyme: What to do in-between doctor visits? Each with a personal Lyme story and both having been down a long road with chronic illness (10 plus years), they recall that time when they felt they were left in the abyss. They realized to reverse an illness, it would take daily care and attention. Now, with the help of their expert faculty Dana and Brent teach a multi-facetted approach to recovering health that includes self-care, healthy mindset, and conscious awareness. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Loka 201544min

Eli Block: OneTaste, Orgasmic Meditation & Flow State - #254

Eli Block: OneTaste, Orgasmic Meditation & Flow State - #254

Eli Block comes on Bulletproof Radio today to discuss what it's like to be an Orgasmic Meditation instructor, choosing the right partner, how OMing helps get you into a flow state, and similarities between porn and empty calories. Eli Block is a teacher, trainer, blogger, and Lead Orgasmic Meditation Instructor at OneTaste. Eli works with clients participating in programs ranging from private coaching and training to OneTaste's professional training and leadership track through all levels of Orgasmic practice. He is a prolific speaker recently having been invited as a guest lecturer for Tony Robbins' coaching staff at their annual retreat as well as Jaiya Ma's VIP Program. A deep lover of the feminine and the lead instructor for the OneTaste's Men's Program, Eli is passionate about realigning our understanding of gender, sexuality, and orgasm with nature. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Loka 20151h 15min

Gerard Mullin: Gut Balance Revolution, Ketosis, & Artificial Sweeteners - #253

Gerard Mullin: Gut Balance Revolution, Ketosis, & Artificial Sweeteners - #253

Gerard Mullin comes on Bulletproof Radio today discuss his new book, The Gut Balance Revolution. As well his thoughts on detox fads, his favorite "superfoods," and how you can start hacking gut bacteria. Dr. Mullin is an associate professor of medicine at The Johns Hopkins Hospital. He is board-certified in internal medicine, gastroenterology, integrative medicine, functional medicine and nutrition. Nationally and internationally renowned for his work in integrative gastroenterology and nutrition, Dr. Mullin has more than 20 years of clinical experience in the field of integrative gastroenterology and earned his master's degree in nutrition while in practice. He is an associate editor of several nutrition and integrative medicine journals. Dr. Mullin was selected by Dr. Andrew Weil to serve as a senior editor for the first book for physicians on integrative gastroenterology by Oxford Press, which was released in May of 2011. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Loka 201556min

Blue Zones: How to live longer and happier lives w/ Dan Burden - #252

Blue Zones: How to live longer and happier lives w/ Dan Burden - #252

Dan Burden and Samantha Thomas come on Bulletproof Radio today to discuss the Blue Zones project, a project that focuses on enabling cities to develop strong, healthy communities and how they have already upgraded longevity across the country. Dan Burden, the Director of Innovation and Inspiration for Blue Zones, LLC, has focused his entire career on helping the world get back on its feet. Dan created the walking audit; a highly interactive way to help people see their community through a sharper, more people focused lens. This popular annual NPSG walking audit workshop is designed to help participants fine-tune their most engaging public interaction skills. Dan illustrates the benefits of sometimes-simple and oft-difficult changes, and provides a roadmap for people to create neighborhoods, streets and cities that are more healthy and better connected. Samantha helps communities-neighborhoods, towns and cities-become healthier, better connected, more accessible and age-friendly. Over the last four years, Samantha has worked in over 100 cities, facilitating walkability, active-living and safe routes to school workshops and developing community-led action plans for communities. She brings to this effort a diversity of experience in community engagement, the power of neighborhood leadership, and civic co-creation from living and working in South Africa for a year, to two years as AmeriCorps volunteer with Amherst H. Wilder Foundation and the City of Saint Paul Office of the Mayor. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Loka 201556min

Summer Bock: Can Fermented Foods Restore Your Gut? - #251

Summer Bock: Can Fermented Foods Restore Your Gut? - #251

Summer Bock comes on Bulletproof Radio today discuss her treatment for food allergies, what a "fermentationist" is, how you can cultivate healthy gut bacteria, and the best foods to eat for gut health. Summer Bock is a Master Fermentationist who guides people to experience a deeper level of healing. Her mission is to radically improve people's health while empowering them to revolutionize the local food system using delicious, local and healthy food. A skilled herbalist with a background in microbiology, she is certified by the Institute of Integrative Nutrition and Columbia University. Summer has created an avid following with her signature programs The Probiotic Power Cleanse, Gut Rebuilding, and the yearlong Fermentationist Certification Program. Enjoy the Show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Loka 201557min

Dr. David Perlmutter: Autism, Alzheimer's & The Gut Microbiome - #250

Dr. David Perlmutter: Autism, Alzheimer's & The Gut Microbiome - #250

Dr. David Perlmutter comes on Bulletproof Radio today discuss the gut microbiome, it's relation to autism and Alzheimer's, prebiotics you should be taking, and the importance of a balanced gut. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Loka 20151h 14min

Jeff Chilton: Medicinal Mushrooms & Industrial Mushroom Cultivation - #249

Jeff Chilton: Medicinal Mushrooms & Industrial Mushroom Cultivation - #249

Jeff Chilton comes on Bulletproof Radio today to discuss medicinal mushrooms, mushroom industry flaws, understanding mushroom spores, and vitamin D in mushrooms. Jeff Chilton has been in the mushroom industry since 1973. He is a founding member of the World Society for Mushroom Biology and Mushroom Products and a member of the International Society for Mushroom Science. Jeff Chilton's company, Nammex, was the first company to offer certified organic mushrooms to the supplement industry in the United States. Nammex extracts are used by many supplement companies and are considered high quality based on scientific analysis of the active compounds. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Loka 201549min

Nadine Artemis: Holistic Dentistry, Root Canal Dangers & Benefits of Essential Oils - #248

Nadine Artemis: Holistic Dentistry, Root Canal Dangers & Benefits of Essential Oils - #248

Nadine Artemis and comes on Bulletproof Radio today to discuss her approach to dentistry, how to whiten teeth naturally, anti-aging in the sun, and why you should avoid fluoride. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Syys 201552min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
rss-valo-minussa-2
psykologia
adhd-podi
esa-saarinen-filosofia-ja-systeemiajattelu
rss-vegaaneista-tykkaan
rss-koira-haudattuna
rss-vapaudu-voimaasi
avara-mieli
rahapuhetta
queen-talk
filocast-filosofian-perusteet
rss-luonnollinen-synnytys-podcast
rss-narsisti
rss-ihana-elamani
rss-niinku-asia-on
rss-psykalab
rss-eron-alkemiaa