TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Jaksot(1344)

TWiV #143 - Live at ASV in Minneapolis

TWiV #143 - Live at ASV in Minneapolis

Vincent, Rich, Julie and Stacey recorded TWiV at the 30th Annual Meeting of the American Society for Virology in Minneapolis, where they discussed the role of neutralizing antibodies in protection aga...

24 Heinä 20111h 5min

TWiV #142 - Viral oinkotherapy

TWiV #142 - Viral oinkotherapy

Vincent, Rich, and Alan discuss a method for identifying viruses of individual environmental bacteria, and the using a picornavirus for oncotherapy.

17 Heinä 20111h 35min

TWiV #141 - Mickey gets HCV

TWiV #141 - Mickey gets HCV

Matt Evans joins Vincent, Dickson, Alan, and Rich to deconstruct a mouse model for hepatitis C virus infection.

10 Heinä 20111h 37min

TWiV #140 - An aptitude for microbicides

TWiV #140 - An aptitude for microbicides

Vincent, Alan, Rich, and Judy Lieberman review the use of CD4 aptamer-siRNA chimeras to inhibit HIV transmission.

3 Heinä 20111h 31min

TWiV #139 - Honey, I shrunk the virus

TWiV #139 - Honey, I shrunk the virus

Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees.

26 Kesä 20111h 20min

TWiV #138 - RISCy business with Raul Andino

TWiV #138 - RISCy business with Raul Andino

Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses.

19 Kesä 20111h 12min

TWiV #137 - Look what the dog dragged in

TWiV #137 - Look what the dog dragged in

The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus.

12 Kesä 20111h 36min

TWiV #136 - Exit XMRV

TWiV #136 - Exit XMRV

Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer.

6 Kesä 20111h 23min

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