10-Minute Biohacking News Update : 1367

10-Minute Biohacking News Update : 1367

This episode covers:


Nano CBD Pain Relief Without Cognitive Side Effects


A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support.

Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm



Moderate Calorie Restriction Slows Biological Aging


A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting.

Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults


FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s


The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair.

Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/


Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules


Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.”

Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged)


Klotho: The Longevity Protein Nears Clinical Reality


The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols.

Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged)


All source links provided for easy reference to the original reporting and research above.


This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates


Thank you to our sponsors!



Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 — Intro

0:19 — Story 1: Nano CBD for Pain Relief

1:53 — Story 2: Caloric Restriction and Aging

3:20 — Story 3: AI Robotic Surgery for Alzheimer’s

4:50 — Story 4: Microbiome Reprogramming

6:05 — Substack Announcement

7:04 — Story 5: Klotho Longevity Protein

8:39 — Weekly Homework

9:31 — Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1429)

Robert Cooper: Rewiring Your Brain & Creating New Habits #261

Robert Cooper: Rewiring Your Brain & Creating New Habits #261

Robert Cooper comes on Bulletproof Radio today to discuss the human brain, how certain words reshape your brain, developing new habits in less than a minute, and the effects of self-talk. Today's guest is a neuroscientist, New York Times bestselling author (with over 4 million books sold), and a leading high-performance business strategist. Robert Cooper serves as CEO of Cooper Neuroscience Lab and Cooper Strategic, a global consulting firm that draws on a peak performance database with more than one million leaders, professionals and teams. Robert brings a long history of working with elite performers and top leaders using neuro- science to get the most out of their brains, their time, and their performance. I sat down with Robert after his keynote address at the 3rd annual Bulletproof Biohacking Conference. He and I talked about the neuroscience of aiming your brain, how to hack the hard-wired human nature that can limit your performance, and how to build new habits that burn better programs into the structure of the brain. Find out more about Roberts work at Cooperstrategic.com. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Marras 201545min

Nir Eyal: Addictive Tech, Killing Bad Habits & Apps for Life Hacking - #260

Nir Eyal: Addictive Tech, Killing Bad Habits & Apps for Life Hacking - #260

Nir Eyal comes on Bulletproof Radio today to discuss life hacking with apps, making addictive products, being addicted to technology and FOMO (Fear Of Missing Out). Nir Eyal writes, consults, and teaches about the intersection of psychology, technology, and business. The M.I.T. Technology Review dubbed Nir, "The Prophet of Habit-Forming Technology." Nir founded two tech companies since 2003 and has taught at the Stanford Graduate School of Business and the Hasso Plattner Institute of Design at Stanford. He is the author of the bestselling book, Hooked: How to Build Habit-Forming Products, which won the "Marketing Book of the Year" award from 800 CEO Read. In addition to blogging at NirAndFar.com, Nir's writing frequently appears in TechCrunch, Inc, The Harvard Business Review, and Psychology Today. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Marras 201558min

Jackie Warner: Why You?re Sick and Tired ? #259

Jackie Warner: Why You?re Sick and Tired ? #259

Jackie Warner comes on Bulletproof Radio today to discuss her workout regiment, why protein is so important, the best sources of nutrient dense calories, and when it's a good idea to be vegetarian. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Marras 20151h 3min

Anthony Meindl: Solving Problems Creatively & Failure as an Option - #258

Anthony Meindl: Solving Problems Creatively & Failure as an Option - #258

Anthony Meindl comes on Bulletproof Radio today to discuss overcoming personal fears, what it's like coaching actors, handling problems creatively, and why failure should always be an option. Anthony Meindl is an award-winning writer/director/producer, creativity expert, inspirational speaker, and artistic director of Anthony Meindl's Actor Workshop (AMAW) with studios in Los Angeles, New York, London, Vancouver, and Sydney. AMAW was honored by Backstage four years in a row and named the Best Acting Studio in Los Angeles (Best Scene Study and Best Cold Read). Meindl is known for teaching the new generation of Hollywood stars led by Golden Globe Nominee Shailene Woodley (Divergent). He is a contributor to the Huffington Post, and Backstage. He is the author of the best-selling creativity book At Left Brain Turn Right, and his new book Alphabet Soup For Grown-Ups is available now. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Marras 20151h 2min

Dr. Amy Shah: Toxic Mold, Intermittent Fasting & Vegan vs Low Carb - #257

Dr. Amy Shah: Toxic Mold, Intermittent Fasting & Vegan vs Low Carb - #257

Dr. Amy Shah comes on Bulletproof Radio today to discuss pros and cons about western medicine, prevention through nutrition, symptoms of toxic mold exposure, vegan vs. low carb diets and intermittent fasting benefits. Dr. Amy Shah is a double board certified MD with medical training From Columbia University Medical Center, Beth Israel Deaconness/Harvard Medical School, and Albert Einstein College of Medicine. Before medical school, she graduated magna cum laude from the famed school of Nutrition at Cornell University. She has a large private practice and since 2013- online. She is releasing her first online health coaching program in October 2015 Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Marras 20151h 4min

Dr. Izabella Wentz: Hashimoto's Thyroiditis & The Root Cause - #256

Dr. Izabella Wentz: Hashimoto's Thyroiditis & The Root Cause - #256

Dr. Izabella Wentz returns to Bulletproof Radio today to discuss Hashimoto's thyroiditis, symptoms of low thyroid function, supplements you should avoid, and an interesting fact about tobacco. Izabella Wentz is a passionate, innovative and solution focused clinical pharmacist. She has had a passion for health care from a very early age. After being diagnosed with Hashimoto's Thyroiditis in 2009, Dr. Wentz was surprised at the lack of knowledge about lifestyle interventions for Hashimoto's, hypothyroidism, and autoimmune conditions. She decided to take on lifestyle interventions as a personal mission in an effort to help herself and others with Hashimoto's. After two years of researching Hashimoto's and Hypothyroidism, she decided to combine emerging knowledge with her quality improvement expertise to run rapid tests of change on herself that led her to discover the root cause of her condition. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Loka 201556min

Dana Walsh & Brent Martin: Lyme Less, Live More - #255

Dana Walsh & Brent Martin: Lyme Less, Live More - #255

Dana and Brent come on Bulletproof Radio today to share their personal experience with Lyme disease and toxic mold exposure, as well as their suggestions on how you can cope with chronic illness. Dana Walsh, featured in the Lyme Documentary UNDER OUR SKIN, and Brent Martin are founders of Lyme Less Live More, identified a giant gap while recovering from Lyme: What to do in-between doctor visits? Each with a personal Lyme story and both having been down a long road with chronic illness (10 plus years), they recall that time when they felt they were left in the abyss. They realized to reverse an illness, it would take daily care and attention. Now, with the help of their expert faculty Dana and Brent teach a multi-facetted approach to recovering health that includes self-care, healthy mindset, and conscious awareness. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Loka 201544min

Eli Block: OneTaste, Orgasmic Meditation & Flow State - #254

Eli Block: OneTaste, Orgasmic Meditation & Flow State - #254

Eli Block comes on Bulletproof Radio today to discuss what it's like to be an Orgasmic Meditation instructor, choosing the right partner, how OMing helps get you into a flow state, and similarities between porn and empty calories. Eli Block is a teacher, trainer, blogger, and Lead Orgasmic Meditation Instructor at OneTaste. Eli works with clients participating in programs ranging from private coaching and training to OneTaste's professional training and leadership track through all levels of Orgasmic practice. He is a prolific speaker recently having been invited as a guest lecturer for Tony Robbins' coaching staff at their annual retreat as well as Jaiya Ma's VIP Program. A deep lover of the feminine and the lead instructor for the OneTaste's Men's Program, Eli is passionate about realigning our understanding of gender, sexuality, and orgasm with nature. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Loka 20151h 15min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
aamukahvilla
rss-sisalto-kuntoon
rss-niinku-asia-on
salainen-paivakirja
psykologia
rss-vapaudu-voimaasi
rss-liian-kuuma-peruna
rss-koira-haudattuna
rss-uskonto-on-tylsaa
rss-eron-alkemiaa
rss-valo-minussa-2
ensihoidon-ja-pelastustyoncast
puhutaan-koiraa
adhd-podi
rss-tripsteri
rss-narsisti
rss-kirja-kateen