Immune 11: Immunomimetic designer cells
Cindy and Vincent describe the construction of a gene network that programs mammalian cells to detect and eliminate bacterial infections. Hosts: Vincent Racaniello and Cynthia Leifer Become a patron o...
18 Elo 20181h 8min
Immune 10: Immune goes viral
The Immune team travels to the University of Maryland for ASV 2018, where they meet up with Rebecca Lynch to explore her work on broadly neutralizing antibodies against HIV-1. Hosts: Vincent Racaniell...
21 Heinä 20181h 15min
Immune 9: Neither mice nor lamprey lie
The Immune team explores the variable lymphocyte receptors of jawless vertebrates, a system of immunity that parallels the structurally unrelated antibodies of jawed vertebrates. Hosts: Vincent Racani...
20 Kesä 20181h 35min
Immune 8: Staying warm with γδ T cells
The Immune team reveals how γδ T cells that synthesize interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer...
25 Touko 20181h 19min
Immune 7: Contradictory complements in Alzheimer's disease
The Immune hosts discuss how the complement system functions, and its role in early synapse loss in a mouse model of Alzheimer's disease. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leife...
18 Huhti 20181h 13min
Immune 6: Potent antiviral antibodies without somatic mutation
The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antibodies against respiratory syncytial virus without somatic hypermutation. Hosts: ...
16 Maalis 20181h 29min
Immune 5: Mother knows best about food allergies
The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prevents allergic reactions in their offspring. Hosts: Vincent Racaniello, Stephanie...
22 Helmi 20181h 40min
Immune 4: Putting the immunotherapy CAR T before the cancer
The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work. Hosts: Vincent Racaniello, Stephanie Langel, and...
23 Tammi 20181h 23min
