The Human Upgrade: Biohacking for Longevity & Performance

Learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity.Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the latest scientific research on aging and longevity. Through his findings, he realized that the body has an incredible built-in healing system that can be activated through understanding the emerging science of longevity. He also managed to reduce his biological age by 20 years effectively.He consistently tackles the topic of inflammation and its impact on aging—or “Inflammaging” as he calls it. “The body only has so many ways to say ouch,” Dr. Mark says. “You have pain. You have inflammation. You have certain things that happen that create all these symptoms, but there're these common roots. So, inflammation is this common root that seems to accelerate as we get older. So, we can measure biomarkers of inflammation that are highly predictive of mortality.”This conversation covers many components of aging, like metabolic flexibility and resilience, mTor, meat- and plant-based protein, nutrition, environmental allergies and food sensitivities, histamine, autophagy, fasting, DEXA scans, and much more!In his newest book, "Young Forever: The Secrets to Living Your Longest, Healthiest Life,” Dr. Mark:shares the knowledge of how to unlock the causes of accelerated aging and treat it as a reversible disease.gives you practical tips for daily habits that will increase your energy and performance.teaches you why you age and what it really takes to live a longer, more vibrant life.Watch this episode on YouTube! Get all the links and resources in the show notes. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% off Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want" https://daveasprey.com/books/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Huhti 20231h 3min

Here's what you must know about the health risks and extensive symptoms of breast implant illness, as well as removal solutions. Dr. Robert Whitfield MD discusses the often-overlooked health risks associated with breast implants. Women who experience breast implant illness have symptoms like brain fog, memory loss, fatigue, joint pain, anxiety, and many more.While there’s not a definitive cause of breast implant illness, a common theory points to an immune system response. Breast implants in the body can lead to persistent foreign body reactions, silicone toxicity, heavy metal exposure, biofilm development around the implants, and free radical/oxidative damage. Over time, these reactions weaken the immune system and cause health symptoms from minor to severe. Your autoimmune response, endocrine system, thyroid & adrenals, and gut all could be affected.Dr. Robert Whitfield MD’s an Austin-based plastic surgeon who’s cared for hundreds of women with breast implant illness, performs breast explants, and teaches other surgeons about this illness and treatment methods. In his years of experience in breast reconstruction for cancer patients, microsurgery, and a deep understanding of the body's reactions to foreign materials, he's developed a unique insight into the world of breast implant illness.This episode serves as a guide to what could be happening in your body, what symptoms to watch for, and breast implant removal options if you suspect you may have breast implant illness. Get more information and take a quiz at https://breastimplantillnessexpert.com and share this important episode with your spouse, a family member, a friend, or a colleague.Watch this episode on YouTube! Find all the links and resources in the show notes. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountFeel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. dangercoffee.com, use code DAVE15 to save 15%Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. vitamindake.com, use code DAVE10 to save 10%See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Huhti 20231h 5min

Get actionable expert tips on testing, nutrition, and lifestyle changes you can do to achieve peak adrenal function. Izabella Wentz, PharmD., aka the “Thyroid Pharmacist,” takes on adrenal fatigue, its symptoms, and the importance of fixing adrenal function in addition to treating thyroid issues in her new book, “Adrenal Transformation Protocol: A 4-Week Plan to Release Stress Symptoms and Go from Surviving to Thriving.”She went deep into the research to develop an actionable guide for you. Her new book helps you identify and mitigate the effects of adrenal dysfunction. If you’re experiencing low energy, insomnia, brain fog, anxiety or burnout, your adrenals may be overworked.You’ll learn why adrenal, immune, and thyroid issues develop as an adaptive mechanism to protect you in times of danger.You’ll also learn how to manage four big stressors that influence your adrenals in a negative way.You’ll find out what lifestyle and mindset changes you can make that turn off danger signals and communicate safety messages to your body.Her protocol emphasizes providing the body with more safety signals to counteract the stress response. She recommends dietary changes, anabolic-focused exercises, and supplements such as carnitine. She also explains the role of adrenal dysfunction in allergies and histamine issues, the dangers of B6 supplements, and the importance of balancing sodium and potassium intake for adrenal health. She suggests Epsom salt baths, a cold bedroom, and paying attention to factors such as H. Pylori, malabsorption, and the CBS gene mutation to address ammonia levels in the body.If you suspect your adrenals are on the fritz, Izabella stresses the importance of a varied and holistic approach to treatment. She urges proper testing and diagnosis of adrenal dysfunction and thyroid issues to build resilience in your body.Watch this episode on YouTube!Find all the links and resources in the show notes. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Micronutrients Boost HRV: https://modemethod.com, use code DAVE to get 15% off your first orderFeel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. Go to dangercoffee.com, use code DAVE15 to save 15%Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. Go to vitamindake.com, use code DAVE10 to save 10%See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Huhti 202354min

Learn about nitric oxide’s crucial role in your body systems, how to naturally produce more of it, and how to supplement effectively and safely. Research scientist Nathan Bryan, Ph.D., has been involved in nitric oxide research for the past 25 years and has made many discoveries in the field. He’s an international leader in molecular medicine and nitric oxide biochemistry. You'll find out how nitric oxide works within major body functions and what you can do to increase your body's natural production of it.Pneuma Nitric Oxide sponsored this episode.Human performance depends on sufficient oxygen and nutrient delivery to organs, tissues, and cells so they can do their job. Nitric oxide controls oxygen and nutrient delivery. It’s now recognized “as one of the most important molecules produced in the body of humans,” Nathan says. “It's a vasodilator, so it controls the regulation of blood flow. It's what's responsible for oxygen and nutrient delivery to every organ, tissue, and cell in the body.”That’s why it’s so important to find the right carrier to effectively deliver this complex and bioactive gas that’s gone in less than a second. Nathan was one of the first scientists to develop a technology to make a solid dose form of nitric oxide.He shares information about Pneuma Nitric Oxide’s key products, like its lozenges, and the N1O1 skincare line. The lozenges open small blood vessels internally and the topicals open superficial blood vessels on the skin to improve blood flow and cellular turnover. He explains how to use a nitric oxide-generating serum on your skin from his N1O1 skincare line that enhances blood flow and promotes wound healing. Nathan presents the anti-aging, performance-enhancing, and nootropic benefits of nitric oxide along with its role in improving stem cell function, controlling telomerase activity, and improving mitochondrial function.He identifies the different isoforms of nitric oxide for you, noting that you should choose a nitric oxide supplement that delivers the same amount of nitric oxide that the body would normally produce. He emphasizes the importance of restoring the body's ability to naturally produce nitric oxide and debunks the use of nitric oxide precursors such as L-arginine and citrulline. He also stresses using safe and effective nitric oxide products.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://n1o1.com and use code DAVE to get 10% off and free shipping.Watch this episode on YouTube! Find all the links and resources in the show notes. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Huhti 202330min

IN THIS EPISODE OF THE HUMAN UPGRADE™... a legacy upgrade conversation with Ingrid Fetell Lee gets into the topic of joy and the influence of your surroundings on your emotions and well-being. You may be hacking your body and mind, but are you embracing joy along the way? This episode shows you how—and explains why it’s essential. You’ll also find out the difference between happiness vs. joy. Fun Fact: While you may be able to fake a smile, you can’t fake joy.Ingrid brought joy into the popular culture conversation with her book, “Joyful: The Surprising Power of Ordinary Things to Create Extraordinary Happiness.” She’s a designer, author, TEDtalk speaker and founder of “The Aesthetics of Joy.” Her work empowers people to find more joy through the purposeful and emotion-driven design of their environments. She’s identified 10 elements of joy that resonate with nearly everyone.EnergyAbundanceFreedom HarmonyPlaySurpriseTranscendenceMagicCelebrationRenewalIngrid explains how to recognize, feel and incorporate more joy into your everyday life.FREE JOY RESOURCES: Downloadable guides: 50 Ways to Find Joy Every Day and Joyspotter’s GuideWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Electrolytes That Taste Good With Zero Sugar Hydration: https://drinklmnt.com//dave, get a FREE LMNT Sample PackGet Your Tickets! 9th Annual Biohacking Conference: https://biohackingconference.comDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Huhti 20231h

IN THIS EPISODE OF THE HUMAN UPGRADE™… former rocket scientist and former law professor Ozan Varol—an expert in creativity, innovation, and critical thinking—says that unlocking your full potential involves reimagining the status quo rather than simply resisting it. “The word resist for me gets in the way because often resistance becomes a different way of conformity, as in you're resisting something but you're not really offering a new path forward,” he says. “So, resistance becomes its own end in and of itself. The goal should be re-imagination.”In this discussion about Ozan’s newest book, “AWAKEN YOUR GENIUS: Escape Conformity, Ignite Creativity, and Become Extraordinary,” you’ll learn to access the best parts of your brain and create your own path as a leader and creator by acting instead of reacting. While people consider those who blaze their own trail as geniuses, Ozan contends that genius is not limited to a select few. Rather, it can be discovered by anyone. He loaded this book with smart tips, examples, things to think about, and things to do. For example, you’ll learn why you should ignore email until noon and spend the most valuable time of your day thinking in creativity. You’ll also learn how spending more time on the “why” than the “what” moves you toward the life you really want to be living. He lays out an action roadmap for you to cultivate your own genius and be in charge of your time and creativity.Watch this episode on YouTube!Find all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% off Feel Dangerously Good! Discover the energy, focus and performance that come from mineralized coffee designed with your biology in mind. Your cells will thank you. https://dangercoffee.com, use code DAVE15 to save 15%Vitamin DAKE & Minerals 101: Foundational vitamins and essential minerals that do the most good across every system in your body. vitamindake.com, use code DAVE10 to save 10%See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Huhti 20231h

In this Episode of The Human Upgrade™...​ Dave talks to David Hinds of Brisbane, Australia, about gut issues and weight loss for men at mid-life. David’s already biohacking, working out, and taking supplements he thinks are the right ones—yet the weight around his mid-section persists.This intervention looks at ways to tackle hard-to-budge love handles and extra mid-section weight with suggestions covering hormones, thyroid, sleep, SIBO, probiotics, supplements, inflammation, the pituitary gland, prolactin, and potassium. This discussion gets into libido and eyesight, too.David’s in his early 50s and a dad to two teenagers. He started biohacking over three years ago when he discovered the Bulletproof Radio podcast (now called The Human Upgrade). He then read Dave’s books, made some life changes, saw the results, and decided 150 years on this rock would be awesome! “So, I'm one-third of the way through life, and my aim is to be in the best physical and mental state possible for all of those years,” he says.Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.Find a full list of the Interventions With Dave episodes here.Listen to this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Protein Bars with All the Good Stuff and None of the Crap: https://rowdybars.com, use code DAVE to get 10% offKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planNature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Huhti 202335min

IN THIS EPISODE OF THE HUMAN UPGRADE™… Vincent Pedre, M.D., explains how consuming too much sugar can lead to insulin resistance and diabetes by causing shifts in the microbiome that reduce insulin signaling. He also highlights how omega-6 fats found in processed foods contribute to inflammation and chronic disease by carrying lipopolysaccharide toxins through cell membranes. For over a decade, board-certified internist and Functional Medicine certified practitioner, Dr. Pedre, founder of Happy Gut Life, has helped people improve their well-being and quality of life by building the foundation of gut health that supports total physical and mental wellness. He believes that healing begins in the kitchen through the foods we eat. He brings together years of research and clinical experience to offer you real solutions in his newest book, “The GutSMART Protocol: Revitalize Your Health, Boost Your Energy, and Lose Weight in Just 14 Days with Your Personalized Gut-Healing Plan.”The balance between good and bad bacteria is both important and nuanced—more microbial diversity in the gut is not always better. "The focus should be on metabolomics, not just diversity when it comes to gut bacteria,” Dr. Pedre says. Another focus includes gut interrelationships and the seven big systems in your body affected by leaky gut: skin, airway, brain, joints, energy, metabolism, and immune system.Watch this episode on YouTube!Find all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Anti-aging Powerhouse: https://spermidinelife.us/dave , use code DAVE25 to save 25% on your first purchaseMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Huhti 20231h 9min