The Human Upgrade: Biohacking for Longevity & Performance

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kratom for Energy & Pain Relief: https://superspeciosa.com, use code DAVE to get 20% off High-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/ Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offSPECIAL OFFERS FOR BULLETPROOF RADIO #866 LISTENERSDental Detox Kit: davesdentalkit.comLED Teeth Whitener: naturalteethwhiteners.com/daveIN THIS EPISODE OF BULLETPROOF RADIO... you’re going to find out how your oral health and gut microbiome are connected.My guest today is Trina Felber, RN, BSN, MSN, CRNA, the creator and CEO of Primal Life Organics, an all-natural health product company that specializes in oral health and skin care.After more than 25 years as a registered nurse and nurse anesthetist, Trina turned her attention to the mouth microbiome and how it influences all your body systems--whether you know it or not.She focuses on oral health as the gateway to internal health, so discuss topics that could give you clues about your own biology:Saliva is the “lifeblood” of the mouth; Red light (and blue!) can improve gum tissue; andWhat you must stop doing when brushing your teeth and why it matters so much to your oral health.Your Saliva: “Saliva is a secretion no one's talking about,” Trina says. “And it's one of, if not the most important secretion in your body, because it does so many things, including nitric oxide production. If you have an imbalance in the microbiome inside your mouth and inside your gut, nitric oxide declines and your body can't produce nitric oxide. … Nitric oxide is a vasodilator, it's related to internal health, it's anti-inflammatory, it creates better sleep and better brain function.”Your Gums: “Red light therapy is going to help with the condition of your gums, it's going to improve the overall environment inside your mouth, and it's going to help with the right environment to grow the right bacteria that in the long-term is going to help with nitric oxide production,” Trina says. “Red light therapy actually penetrates your gum tissue and will increase blood flow and reduce inflammation of the gum tissue.”Your Brushing Habits: “Brushing too hard, we don't think about it, but it's common sense, but we still do it because you feel like you need to scrub to get your teeth clean and your gums,” Trina says. “But a lot of people just brush way too hard. It's really a soft motion. The softer you brush, the more you actually stimulate detoxification and increase blood flow. It's like a massage. Sometimes when you massage too hard, you create inflammation, you create more problems. And the softer that you massage, like lymphatic massages, are extremely, there's no depth to them. It's very light touch.” (Even with a sonic toothbrush!)Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Loka 20211h 11min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Find Out Your Biological Age: https://glycanage.com, use code DAVE to get 20% off testing packages Get Salty AF: https://drinklmnt.com/dave, from unflavored to classy combos like mango chili to the new watermelonControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIN THIS EPISODE OF BULLETPROOF RADIO...Do you know why you make choices that are bad for you? Or why you end up with burnout, bad diets and other things that cause you harm, when you know you’d be better off choosing something else? This episode cuts through the noise, everything you’re sold and told to want, and helps you answer those very questions.Luke Burgis researched and studied the theory that underlies your tendency to follow other peoples’ wants, called mimetic desire. Explored by prominent French thinker René Girard, mimetic theory of desire says humans don’t want anything autonomously and independently. “Girard discovered that we come to desire certain things not through biological drives or pure reason, nor as the longing of our deepest, most authentic selves, but through imitation,” Luke says in his book, “Wanting: The Power of Mimetic Desire in Everyday Life.” Desire, as Girard used the word, does not mean the drive for food or sex or shelter or security. But after meeting those needs, we enter the domain of desire. And knowing what to want is much harder than knowing what to need.”In studying the work of Gerard, Luke realized that his goals and dreams were a product of other people’s expectations of him and he was actually following the desire of what he was seeing in others (that’s why he was miserable, burnt out, in poor physical health and felt horrible). “The truth is that desires are derivative, contagious, and therefore competitive, and that’s why they often lead to conflict,” Luke explains. “The lie is that I want things entirely on my own, uninfluenced by others. By rejecting the truth, I deny the consequences of my desires on other people, and theirs on me.”Luke and I dive into how to get past the innate desires of success and wealth that most of us are taught to value and really move into your own individual dreams and self-desires. “Mimetic desire exists on a spectrum,” he says. “And that there are some things that can't be explained medically at all. Something beautiful like a sunset, or like a beautiful woman that I'm attracted to. There are very clear scientific sort of physiological things going on there. So, let's make a distinction. Mimetic desire exists on a spectrum where those hardwired physiological things like thirst and hunger, those have been met, right? And we're sort of now in a more abstract world.”Armed with this knowledge, you can make better choices about who you trust and build self-awareness around your choices to empower your own life. You can find holistic models that work for you in all areas of your life (not just at your job), and why those models are important to find sooner rather than later.“​​The constant looking to what other people are doing or saying or wanting, or achieving, is just the fastest way to be miserable for one thing, but also the fastest way to miss opportunities, because we're just constantly looking to our right and our left rather than forward or up,” Luke says.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Loka 20211h 27min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Light Therapy: https://joovv.com/dave, use code DAVEOzone for Healing, Cognition & Performance: http://www.drsozone.com/asprey. Use code UPGRADED10 to save 10% on Dave’s Bulletproof BundleCustomized Nootropic Stacks: https://nootopia.com/dave, use code DAVE10 to save 10% on your first orderSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go tohttps://justthrivehealth.com. Use code “ASPREY” to get a 15% off discount.IN THIS EPISODE OF BULLETPROOF RADIO...Research microbiologist Kiran Krishnan, Ph.D., explores the world of microorganisms inside your body. He studies the human microbiome and knows just how much inflammation damages your gut and how your immune system fixes it.He’s particularly adept at explaining practical ways to apply the latest science he’s uncovering.His expertise lies in the newest frontier in microbiology—gut commensal spore bacteria. He partners with Just Thrive Health on prebiotics, probiotics and other gut health product development.When he was on the show previously, we got into probiotics and immune health. (Don’t miss those! Support Immune Health in Two Steps: Modulate Gut Bacteria & Neutralize Inflammation – #677 and Armor-Plated Immortal Probiotics from Space – #629. This time, he makes connections between your microbiome and immune function.“The inflammatory response is the biggest driver of gut related damage that occurs,” Kiran says. “You can also eat foods that are absolutely toxigenic to your microbiome.”The good news? Up to 80 percent of your immune system lies in your digestive tract, Kiran explains. “Your immune system is there, ready and waiting to help with the situation.”In this episode, you’ll learn that lipopolysaccharide (LPS) is the unknown villain of virtually everything. Kiran says it causes damage to the brain, contributes to metabolic disease, drives Alzheimer’s, Parkinson’s, and is the No. 1 driver of diabetes (to name a few).“LPS is the most pervasive toxin we have to deal with and it’s an endotoxin, which is a key because we can’t get away from it,” Kiran says.Kiran has a strict research background in the fields of molecular medicine and microbiology. For nearly 20 years, he’s conducted dozens of human clinical trials in human nutrition through his research organization: Clinical Research Organization.His recently published leaky gut study showed reversal of gut enteropathy within 30 days. He’s now involved with a longer, more extensive leaky gut trial. His current research also includes nine other ongoing human clinical trials. Some test the effect of gut commensal spore probiotics on conditions like Thyroid/Hashimoto’s, Irritable Bowel Syndrome and liver failure.Listening to this extensive interview, you’ll find out cool stuff, like what faecalibacterium prausnitzii is and how it helps you.“We all have all kinds of damage occurring in our large bowel all the time,” Kiran says. “But if you have faecalibacterium, it's constantly repairing it. If you don't have faecalibacterium, at some point, the damage overcomes the repair and you start getting significant inflammation in lining which then puts you at risk for things like inflammatory bowel disease. Right, so we're constantly battling this state of damage, oxidative stress, inflammation, and all that, and then repair recovery and so on. And then as it turns out, microbes are so important for that repair and recovery phase.”You’ll also gain new perspective of your own body biomes and the broader world: “I've always referred to the human system as a walking, talking rainforest,” Kiran says. “We are a holo-biome which is a super organism. We are an organism made up of a collective of organisms that together in a certain balance will function and work. But we are also in constant osmosis with the ecosystem, and we're designed to be that way.”Another positive for your gut and immune health is the vast number of microbial genes in your system.“We have such limited amount of genetic capability as a species,” Kiran says. “We barely have enough genetic material as an earthworm does, and so we're not that cool or sophisticated. What makes us as sophisticated as we are, is the two and a half million or so microbial genes in our system. And so, being able to outsource functionality to microbes is a big part of being human. There are sets of organisms that we have outsourced through the course of evolution, the ability to modulate and monitor the rest of the microbiome. We're finding that when you start putting in these microbes back into your system, you really start getting the positive changes. They start refereeing the ecosystem and making things more balance and improved.” Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Loka 20211h 32min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Solve Sitting: https://us.harmonidesk.com/, use code DAVE20 and get $20 off any standing deskTrack Your Health: https://info.insidetracker.com/dave, save 25%Breathe More, Snore Less: https://mutesnoring.com/DAVE; use promo code DAVE10 to save 10%and get free shippingControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIn Part 1 of our two-part episode with John Jaquish, Ph.D., I talked with him about building bone density—an important factor in your strength and longevity. Don’t miss! Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D., with Dave Asprey, Part 1 – #862.This inventor, author, and scientist created OsteoStrong and the X3 System, a series of devices that combine rehabilitation and advancements in human physiology to build bone density. His extensive research into bone density and strength found that you can approach weight lifting much differently than you may think.“It appears that the most biological adaptation comes from not the area under the curve, the total volume of work you did, but has to do with how quickly did you go from zero to 100 and back to zero,” John says. “So, a very brief spike of almost anything causes way more adaptation than spiking up to 70% and holding it.”Now in Part 2, our conversation dives into John’s other findings and lifestyle choices, both as a public figure, a mentor for professional athletes and a fasting enthusiast. We go off the beaten path on a few things:Anabolic rebound after fasting (what fasting does to build muscle mass)Tendon mutations (and how they make people outrageously strong)Taking Viagra (or other non-pharmaceuticals) and carbs to trigger a muscle cell splittingThe difference between fructose, glucose and sucrose (is there any real difference in the body?)We also talk about ways to eat for strength and the quest for longevity that guides him. He knows about the tempting danger of eating to only look good (but you feel like crap). He offers tips to make sure you don’t go there.Check out John’s book to learn more: Weight Lifting Is a Waste of Time: So Is Cardio, and There’s a Better Way to Have the Body You WantEnjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Loka 202144min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nervous System Recovery: https://apolloneuro.com/pages/dave10 to get 10% off an Apollo Neuro deviceControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProIN THIS EPISODE OF BULLLETPROOF RADIO...Inventor, author, and scientist John Jaquish, Ph.D., downloads his knowledge about the importance of bone density. When his mom was diagnosed with osteoporosis he set out to develop bioDensity, a system that builds bone density by triggering the effects of weightlifting without the risk of injury. He’s talked about it on Bulletproof Radio before.He’s developed a way to put on muscles three times faster than you can by weightlifting. I’m asking him to explain why that matters and what devices and routines can help you get there. He created OsteoStrong and the X3 System, a series of devices that combine rehabilitation devices and advancements in human physiology to build bone density. Why so much focus on bone density?“You're avoiding the potential for fragility fractures later in life,” John says. “The bone you build through the osteogenic loading process, through this heavy loading, you're getting bone built that's going to last in your body for 30 years. It doesn't go away like muscle. Detraining of a muscle starts in 10 days. If you stop working out, you lose your muscle in 10 days. It takes you 30 years to lose the bone.”In part one of this two-part episode, we talk about John’s inventions and research, as well as the three aspects of strength that most people don’t think about when they start a fitness routine. You’ll learn what vitamins and protein habits matter and what kind of exercise truly increases your longevity.You can also check out John’s book: "Weight Lifting Is a Waste of Time: So Is Cardio, and There’s a Better Way to Have the Body You Want"And stay tuned for Part 2 of this episode, coming soon!Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Syys 202139min

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Enjoy!Here’s the current lineup for episode #15:A ketogenic diet impacts brain cancer.A surprising connection links calf muscles, blood pressure, and dementia risk.A dose of sunlight boosts romantic passion.An energy process involves brain cells, memory and sugar levels.A bunch of benefits support time-restrictive eating.An innovative way to transport mouse sperm.EPISODE SPONSOR: Monitor your glucose and ketone readings using the GK+ meter and sign up for MyMojoHealth to start connecting today. Go to keto-mojo.com/mymojohealth. Use code DAVE15 to get 15% off a meter kit — MyMojoHealth is free!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Syys 202112min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Measure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVE Minerals for Cellular Health: https://www.beamminerals.com, use code DAVE to get 20% offControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERSGo to https://nootopia.com/dave and use code DAVE10 to get 10% offIN THIS EPISODE OF BULLLETPROOF RADIO...We’re going deep on all things nootropics. Stacks, timing and what works for your brain.I didn’t want to be the guy who made nootropics. I wanted it to be the fact that it’s possible, therefore, let’s all do it. I mean, take them and let’s all make them. We need creators who build stuff that’s real. I just want people to see it was real so that we could all build it.You’re going to learn a lot in this episode, like:The promise of nootropics vs. the reality of nootropicsProblems with typical nootropicsHow brain chemistry and nervous systems are incredibly uniqueHow every high-performance state has a corresponding neurochemistry stackNine Nootopia base blends that have specific goals and purposesWhy Nootopia nootropics are differentTips to get the most out of your nootropics One of today’s guests has been on the show several times to talk about psychobiotics, magnesium, enzymes and blood sugar.As co-founder of BiOptimizers, Matt Gallant keeps researching and innovating ways to keep your whole body healthy. He sees important connections within body systems and finds unique ways to maximum human performance. He especially likes the brain and will be talking about new developments in nootropics that can be customized to your own body system.Matt Gallant: “A lot of nootropics rely on brute force,” Matt says. “They hammer one receptor or one pathway and they just push it to the max which has negative consequences, receptors downregulate, you can have more side effects. As a former addict, I thought, and I was hardwired to believe that more is better. And now I know better and optimal is better. So, it's about really finding the optimal dose for each person. And that's why we're all about customization and personalization.”He’s joined by Mr. Noots, his partner in custom nootropic development. Between ages 5 and 10, he built radio, conducted dangerous chemistry experiments and built a Helium-Neon Laser from scratch. His favorite childhood activities were science, chemistry and physics. He spent his 20’s in the US Air Force, which was the perfect platform to become an endurance athlete and eventual bodybuilder. Life happened and as Mr. Noots moved from sick to superhuman, he dove deep into performance-enhancing nutrition. That, in turn, led him to become a Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia.“This is one of the things where I want everyone listening to just say, "Okay, I admit to myself that it is possible for plant extracts or other compounds to improve cognitive function because it's abundantly obvious,” “says Mr. Noots.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Syys 20211h 22min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Copper-Technology Pillow: https://www.envypillow.com, use code DAVE15 to get 15% off any pillowNatural Memory Foam Mattress: www.myessentia.com, use code DAVE25 to get 25% off any mattressBetter Food Delivered: https://www.greenchef.com, use code DAVE100 to get $100 off your first order (U.S. delivery only)Trigger Autophagy: https://spermidinelife.us/dave, use code DAVE25 for 25% off your first month’s orderIN THIS EPISODE OF BULLLETPROOF RADIO...You've been asking for experts who can talk about food that's in line with the way we evolved as humans, so this episode brings together two guests who are experts on ancestral eating: Dr. Paul Saladino’s research on the carnivore diet, with Nora Gedgaudas decades of research on paleo and keto diets. The conversation dives into the dangers of vegan and vegetarianism, why meat should be a core part of your diet, and how plants might be more harmful to eat than you think. Both put chronic disease at the core of their research and have spent years of research and heart finding eating habits that give you the greatest quality of life. Dr. Paul Saladino is a certified functional medicine practitioner who says yes to meat and no to plants. Dr. Saladino’s work promotes the use of science-based information to deeply understand the root causes of illness and provide individualized care that goes beyond traditional pharmacological treatments.“Eat nose to tail with organ meats, with well-raised red meat and organs, and you will thrive,” Dr. Saladino says. “Plants hate us and if we ignore the fact that plants exist on a toxicity spectrum and make plant toxins, which are defended chemicals, we are abandoning a whole bunch of people who could get really well by eliminating the most toxic plants from their diet.”Want to learn more from Dr. Saladino? Listen to two full podcasts with him and check out his book:The Carnivore Conversation with a Surprisingly Sweet Twist: Paul Saladino, M.D., with Dave Asprey– #735Kick Veggies to the Curb and Go Full Carnivore – Dr. Paul Saladino #621Book: THE CARNIVORE CODE: Unlocking the Secrets to Optimal Health by Returning to Our Ancestral Diet Nora Gedgaudus is an internationally keto and ancestrally based nutrition specialist and author. She combines extensive research with evolutionary physiology, biochemistry, metabolism, nutrition, and chronic and degenerative disease for mind-body health and longevity.She’s created her own program called PRIMALGENIC, based on her 20 years of knowledge of ancestral and modern eating, and the paleo and keto diets.“What’s incumbent upon us in the face of so many things we feel like we can't control is to take control of what we can, be aware, understand as much of this as we can and find ways of strategizing our way around the system and develop that firsthand knowing of where your food comes from, as much as humanly possible,” Nora says. “And, educate yourself and take responsibility for as much as you possibly can.”Want to learn more from Nora? Listen to two full podcasts with her and check out her books:Under Attack: The Evolution of Ancestral Nutrition – Nora Gedgaudas #594Nora Gedgaudas: Food for Consciousness – #136Book: Primal Body, Primal Mind: Beyond Paleo for Total Health and a Longer LifeBook Rethinking Fatigue, What Your Adrenals Are Really Telling You and What You Can Do About It Check out more articles from Dr. Saladino and Nora about ancestral eating on the Dave Asprey blog: Is the Carnivore Diet Healthy? Not Unless You Do ThisHow to Eat Organ Meats: Beginner to AdvancedAre Humans Vegan or Omnivores? A Look at DigestionAre Humans Vegans or Omnivores? The Answer is All in Your HeadEnjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Syys 202126min