The Human Upgrade: Biohacking for Longevity & Performance

In this episode of Bulletproof Radio, I’m hosting a return guest because he’s doing some truly innovative work in the area of human health span and lifespan. James Clement is a lawyer and entrepreneur turned research scientist who has devoted the last two decades to understanding the science of life extension. His new book, “The Switch: Ignite Your Metabolism with Intermittent Fasting, Protein Cycling, and Keto,” is the result of years of scientific investigation that started with a curiosity of the human body’s mTOR/autophagy switch. Autophagy is a natural process that recycles and renews damaged cell parts and removes pathogens to keep us healthy. Like a dimmer “switch,” mTOR can turn autophagy up or down. A switch, James says, that’s at the center of nearly every anti-aging drug, nutraceutical, diet, and health choice that we make. “The purpose of the book is really to go into this molecular biology mechanism inside the cell, which is about as basic as you can get,” James says. “If you're not working these mechanisms properly, then it doesn't matter what your good intentions are, or the practices that you think you're following.”In our interview James gives practical tips on how we can activate autophagy through different regimens, such as calorie restriction, intermittent fasting, very-low-carb diets, exercise, or supplements. When it’s switched up, autophagy restores our natural metabolism, slows the aging process, and helps fend off diseases from diabetes, to cancer, to heart disease. James also is known for his Supercentenarian Research Study, which he started in 2010 and received international attention. Through worldwide scientific collaborations and in his own laboratory, his work focuses on advancing biomedical discoveries.Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Tammi 20201h 1min

In this episode of Bulletproof Radio, my guest explores the underwater world as one of the greatest cave divers on the planet. She is considered this generation’s Jacques Cousteau. Canadian Jill Heinerth has gone into places in the world where no one had gone before.“The adventure seeker, the novelty seeker, the sensation seeker isn't necessarily risky in that foolish sort of way,” Jill says. “We're not adrenaline seekers necessarily. It doesn't mean we're dangerous. It doesn't mean were death-wish kind of thing. It just means we're out and interested in stimulation, learning, curiosity, and new things.”She’s dived deeper into caves than any woman in history and set a women's world record for deep cave penetration. She became the first person to dive the ice caves of Antarctica, going further into an underwater cave system than any woman ever. “When I do choose to take risks, I'm very, very careful about assessing risks, trying to prevent as many things that could go wrong, pre-visualizing what could happen underwater, and then ensuring that I have the right training, the right personnel, the right equipment, and redundancy with me, so that I can handle that worst case possible scenario,” Jill says.She’s completed more than 7,500 dives in her career so far and says, “We are capable of so much more than we could possibly imagine.”Considered a legend in the diving community, she's spent more than three decades in submerged caves around the world partnering with National Geographic, NOAA, and various educational institutions and television networks worldwide. She’s also a writer and award-winning photographer and filmmaker who takes a keen interest in the health of our Earth’s oceans.In recognition of her lifetime achievement, Jill was awarded the inaugural Sir Christopher Ondaatje Medal for Exploration. Established by the Royal Canadian Geographical Society in 2013, the medal recognizes singular achievements and the pursuit of excellence by an outstanding Canadian explorer. She also is the first Explorer in Residence for the society.Jill says cave diving is “one of the most dangerous, yet exhilarating, pursuits in the world.” In our conversation, we talk about her adventures underwater and how her survival depends on how she balances risk, fear and the right amount of breathing.“I'm scared all the time,” Jill says, “because I think being scared means that I care about the outcome.”Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Tammi 20201h 6min

In this episode of Bulletproof Radio, my guest is someone who has cracked the code on a fundamental part of how human behavior works when it comes to forming new habits.Behavior scientist BJ Fogg, Ph.D., founded the Behavior Design Lab at Stanford University and is considered the leading scientific authority on habits.“It really is surprising to people how quickly you can form habits,” BJ says, “and there are certain habits that have this transformative impact on you.” There's one habit in particular, called the Maui habit, that he suggests for absolutely everyone. Keep listening to find out how to do it!His behavior model is easy to learn and easy to apply to everyday life… and doesn’t include willpower. “The thing that wires a habit in is not repetition,” BJ says, “it's the emotion you feel when you do the behavior.” He explains that behavior happens when three elements come together at the same moment: motivation, ability, and a prompt. This is going to be the episode that sets you on the path to creating habits that last. Why? Because BJ will introduce you to the science behind forming “Tiny Habits: The Small Changes that Change Everything ” and give you the tools you need to hack your own behavior.“The book does two things at once,” BJ says. “It defines what behavior design is and gives the models and methods of behavior design. Then more specifically, it walks people through step-by-step tiny habits so people can create habits quickly and easily.”Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Tammi 202056min

In this episode of Bulletproof Radio, my guest is a TV chef, holistic nutritionist, and award-winning entrepreneur and inventor with more than 25 years of experience in the food industry. Mareya Ibrahim hosts the popular Facebook Live show “The Real Dish” and the "Recipes for Your Best Life” podcast. She also founded Grow Green Industries and co-invented the patented eatCleaner line of products.She believes in food flexibility while still focusing on a core system that works, “where you're exercising your metabolism, you're flexing your taste buds, you're exploring a variety of different macronutrients and having fun with food,” she says.Mareya and I talk about her new book, "Eat Like You Give a Fork: The Real Dish on Eating to Thrive," the nuances of clean eating, and why grains aren’t always the enemy.“At the end of the day, I think what's really important is that we focus on the quality of the food that we're getting and that we eat with intention,” Mareya says.Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Tammi 20201h 12min

In this episode of Bulletproof Radio, my guest defies aging by pushing the limits of his own endurance as an athlete and adventurer well into his sixth decade. After a 20-year hiatus from competitive fitness, Robert Hamilton Owens took it up again at age 50. By age 65, he felt ready to take on five of the world’s toughest endurance events. IN. ONE. YEAR. He competed in an 8-day race over 200 miles across Greece; a combination run/ocean swim event lasting more than nine hours; an Ironman Triathlon; seven marathons in seven days on seven continents; and a 50-hour challenge modeled after a Navy SEAL-style Hell Week. Yet, Robert says; “I'm an average guy. And what I learned in this process was that if an average person will continue to do the right things and persevere, they'll do far more than they think they can ever do.” In our conversation, we talk training styles, grit, toughness, and what it takes to find your “why” and keep going. That includes being vulnerable and asking for help.“Most people will hit a natural mental ceiling,” Robert says. “Your mind is geared to protect you. You think thoughts to protect you, you don't want to be hurt. And yet to get to the places you want to go, you're going to have to go through pain; mental pain, emotional pain, relational pain, financial pain, situational pain. And you don't want pain. None of us do. But the only way to grow is to embrace that pain.”Enjoy the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Tammi 20201h 9min

In this episode of Bulletproof Radio, my guest tackles a topic in her newest book that has far-reaching implications for just about every aspect of human health—sugar. And she talks about it a way that's really useful because sugar is an emotional, psychological, and physical and biochemical thing all at once. Not quite heroin but not that far away.“Sugar has the tightest grip on us, right?” Michele Promaulayko says. “Even the "healthiest" people I know have a problem with sugar. As I was developing “Sugar Free 3,” every single person I spoke to said, "I need that." And they all do need it because we're a nation of sugar addicted people.”We discuss the insidious ways added sugar shows up in our food supply and how we’re unintentionally consuming it because it’s hiding in so many foods. “The frenemy,” says Michele in “Sugar Free 3: The Simple 3-Week Plan for More Energy, Better Sleep, and Surprisingly Easy Weight Loss!”. “And that’s exactly what sugar is. … Sure, it acts life your most supportive BFF, there for you at all hours, especially the late nights when you think you need it most. But when you stop to really thing about it, sugar takes way more than it gives.”In our conversation, Michele suggests genius ways to use aromatherapy to curb cravings, gives practical tips on how to reset your palette, and recommends ways to loosen sugar’s grip. You can find even more tips in the book or on the new video series platform Sugar Free 3 on Openfit.Michele is an award-winning print and digital editor, journalist and author. As the former editor-in-chief of Comopolitan magazine, Yahoo Health, and Women’s Health magazine, she has been an influential voice for health, wellness, and women’s issues for two decades. She’s now editorial-director-at-large for THE WELL—a new health ecosystem—where she continues to be a leader in the modern wellness conversation.Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Tammi 202052min

In this episode of Bulletproof Radio, my guest is a scientist and entrepreneur in the field of genomics who is regarded as one of the most innovative leaders in the emerging personalized medicine and lifestyle genomics space. Mansoor Mohammed, Ph.D., president and chief scientific officer of The DNA Company, is considered to be a pioneer in medical genomics. He’s a classically trained molecular immunologist who has received academic and industry awards, published numerous papers, and holds patents in the general fields of molecular diagnostics and genomics research.“Functional genomics is about understanding the DNA behaves in every definition like a language,” Mansoor says. “It has vocabulary, i.e., the genes. But it also has grammar, sentence structure, syntax, nuances. You've got to be able to read genetic structure at the holistic level.”Listen on to learn more about how advancements across the exciting field of functional genomics are influencing personalized medicine and how The DNA Company is approaching female hormone health.“We've chosen female health as our primary initial focus, and more specifically, taking a functional genomics’ view of the mechanisms that drive hormone health in women,” Mansoor says.Enjoy the show! **Special Offer for Bulletproof Radio Listeners**The DNA Company is offering a free 30-minute consultation with a clinician with the purchase of either the Male or Female Hormone Profile. Once your report is ready, one of The DNA Company’s trained clinicians will review your report and answer any questions you may about your results. Enter "DAVE" in the clinician code section during check out and you will receive a link to book your free consultation when your report is ready. Once The DNA Company receives your completed saliva sample, you can expect delivery of your reports within 6 to 8 weeks. Access the Female Hormone ProfileAccess the Male Hormone ProfileFor clinical practitioners who want to register for The DNA Company’s Functional Genomics Training Program, access the waiting list here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Tammi 20201h 8min

In this episode of Bulletproof Radio, my guest is Lance Dalleck, Ph.D., a professor of Exercise and Sport Science at Western Colorado University in Gunnison, Colorado.Lance's research validates the science behind CAR.O.L. FIT AI, a game-changing exercise bike that delivers peak fitness in just 40 seconds. And you don't even have to break a sweat.He shares some interesting findings that support the effectiveness of high-intensity interval training on the CAR.O.L. bike, an AI-powered, interactive exercise bike with self-learning algorithms. CAR.O.L. stands for CARdiovascular Optimization Logic. You may remember that I talked with the CAR.O.L. FIT AI co-founders on episode #615 of Bulletproof Radio about how to hack your cardiovascular system with the CAR.O.L.“With a 20-second sprint, you're increasing your energy demand above rest substantially,” Lance says. “That's a severe disruption to your homeostasis. And as a result of that, you're putting in motion a variety of upregulation of metabolic pathways that allow you to provide energy that will regenerate ATP so that you can keep sprinting for 20 seconds. And the research is pretty clear that we've identified that minimum time that turns on these pathways, 20 seconds, two bouts a day, and that's sufficient.”Lance teaches in both the Exercise and Sport Science and High-Altitude Exercise Physiology programs. He researches primary and secondary prevention of chronic diseases through evidence-based interventions like exercise and nutrition and quantifies the energy expenditure of outdoor and non-traditional types of physical activity. His research into CAR.O.L. culminated in a paper published in the International Journal of Environmental Research and Public Health: “Reduced Exertion High-Intensity Interval Training is More Effective at Improving Cardiorespiratory Fitness and Cardiometabolic Health than Traditional Moderate-Intensity Continuous Training.”Lance has published more than 100 peer-reviewed articles, delivered 30 conference proceedings, and written 10 book chapters. He is on the Scientific Advisory Panel for the American Council on Exercise.Enjoy the show!**Special Offer for Bulletproof Radio Listeners**To receive $150 off your purchase of a CAR.O.L FIT AI-powered, interactive exercise bike, enter promo code "DAVE" at checkout.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Tammi 20201h 1min