The Top Line

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning.

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Jaksot(100)

Fixing failed spray-dried formulations faster (Sponsored)

Fixing failed spray-dried formulations faster (Sponsored)

Spray-dried dispersions are widely used, but they do not always deliver expected results. In this sponsored episode of The Top Line, host Stephanie Butler speaks with AustinPx Chief Scientific Officer...

20 Huhti 32min

AI brings precision to pharma content decisions (Sponsored)

AI brings precision to pharma content decisions (Sponsored)

Artificial intelligence is increasingly shaping how pharma companies approach content strategy and decision-making. In this episode of The Top Line, Kristen Pilkiewicz, EVP and executive creative dire...

20 Huhti 9min

Roivant’s CEO thinks China is a ‘red herring’

Roivant’s CEO thinks China is a ‘red herring’

China’s biotech rise has been a persistent concern for federal health leaders, Congress, and many biopharma executives. But to Roivant CEO Matt Gline, the country is nothing more than a red herring. ...

17 Huhti 37min

The top 10 pharma R&D budgets of 2025

The top 10 pharma R&D budgets of 2025

The wait is over. Fierce Biotech has released its annual ranking of the top 10 pharma R&D budgets of 2025—offering a clear look at which companies are spending the most on innovation and how those inv...

10 Huhti 13min

An update on the pharma industry’s reshoring effort

An update on the pharma industry’s reshoring effort

After a wave of high-profile pledges to bring pharmaceutical manufacturing back to the United States, a clearer picture of what reshoring actually looks like is starting to emerge. Tens of billions of...

3 Huhti 21min

Pulse check on Lilly's GLP-1 fortunes

Pulse check on Lilly's GLP-1 fortunes

While Lilly’s position in the obesity market and wider GLP-1 space has remained largely unshakeable in recent months, a crack in the company’s armor may be forming, according to at least one analyst. ...

27 Maalis 16min

Avoiding 11th hour surprises in clinical trials (Sponsored)

Avoiding 11th hour surprises in clinical trials (Sponsored)

In this episode of The Top Line, host Chris Hayden speaks with Olive McCormick, Head of Quality and Qualified Person at Almac Clinical Services about why late‑breaking issues in clinical trials pose s...

23 Maalis 18min

What Xaira is building after its $1B fundraise

What Xaira is building after its $1B fundraise

Since Xaira’s eye-popping $1 billion fundraise in 2024, the company has said relatively little in public. That’s made it one of biotech’s more closely watched black boxes: a company with enormous back...

20 Maalis 33min

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