TWiV 819: How to stall a copy machine
TWiV explains how remdesivir inhibits the SARS-CoV-2 RNA polymerase: the drug is incorporated into the growing RNA chain and causes synthesis to stall when the drug clashes with an amino acid in the a...
21 Loka 20211h 40min
TWiV 818: Thor's hammer
The TWiVers review phase 3 efficacy and safety results for the Novavax COVID-19 vaccine, effects on the neonatal immune system caused by maternal infection with SARS-CoV-2, and NHC, the metabolite of ...
17 Loka 20211h 56min
TWiV 817: COVID-19 clinical update #84 with Dr. Daniel Griffin
In COVID-19 clinical update #84, Dr. Griffin discusses childrens' antibody response to vaccination, phase 3 results of Novavax vaccine, heterologous vaccination, antithrombotic therapy, EUA for molnup...
16 Loka 202145min
TWiV 816: Long COVID and ME/CFS with David Tuller
David Tuller returns to TWiV to revisit his work to expose the methodological and ethical problems with the PACE trial, and the post-acute sequelae to SARS-CoV-2 infection, also known as long COVID. H...
15 Loka 20211h 9min
TWiV 815: MIS-C with Moshe Arditi and Ivet Bahar
Moshe and Ivet join TWiV to discuss their finding that MIS-C is a consequence of a superantigen in the spike protein of SARS-CoV-2 that causes activation of a skewed population of T cell receptor bear...
10 Loka 20212h 2min
TWiV 814: COVID-19 clinical update #83 with Dr. Daniel Griffin
In COVID-19 clinical update #83, Daniel Griffin discusses upcoming FDA discussions on vaccines, strategies to prevent transmission at youth camps, outbreaks at summer camps, impact of vaccination on t...
9 Loka 202149min
TWiV 813: COVID-19 at the European Society for Clinical Virology
From the 2021 online meeting of the European Society for Clinical Virology, Vincent speaks with meeting speakers on COVID-19 vaccines, immunity, how countries responded to the pandemic, and how to pre...
7 Loka 20211h 59min
TWiV 812: Bespoke capsids delivered
TWiV considers lessons learned from COVID-19 about emergency drug use during a pandemic, and selection of AAV capsids to produce vectors that efficiently deliver genes to muscle cells. Hosts: Vincent ...
3 Loka 20211h 51min
