Unexpected Elements

Mutant strains of SARS-Cov2 have been identified not only in the UK, where it was first identified, but also in at least 30 other countries. And to complicate matters, another alarming variant, with some similar mutations, has arisen in South Africa. Roland Pease talks to Ravi Gupta, a virologist at Cambridge University and Tulio de Oliveira of the University of KwaZulu Natal about these new strains. There’s only so much that can be learned about the virus by looking at the patients it infects. Thanks to techniques developed to study HIV, Ebola, flu and other viruses in the past, researchers have methods for growing key parts of viral structures in the lab and watching closely how they behave in cell cultures. Jeremy Luban of the University of Massachusetts and Alli Greaney at the Fred Hutchinson Cancer Research Center talk to Roland about how they are studying the biology of the mutations to discover how the new strains might respond to vaccines.And, one of the more surprising consequences of the pandemic has been the trend for people wanting to move out of cities and back to the countryside. Not everyone has that privilege of course, but undoubtedly for some living in urban areas during lockdown, the lack of access to green spaces took its toll on their mental health and physical well-being. Now, with renewed hope of a global vaccine roll-out, ensuring more people have better access to nature is more important than ever, especially in cities of glass, steel and concrete. Italian CrowdScience listener Enrica loves nothing better than walking along the verdant riverbank near her home after a hard week at work. But is this activity doing more than making her feel good? Is it having an actual effect on her health? Presenter Anand Jagatia meets Enrica and visits a radical scheme in the city of Milan, where officials have been working hard to increase urban green features and have committed to planting 3 million trees and building twenty new parks by 2030.One such idea is the innovative Bosco Verticale - or vertical forest, planted up the side of two high rises apartment blocks. Amongst other benefits It’s hoped it could provide cooling microclimates to reduce the dangers (Image: Swab test. Credit: Getty Images)

10 Tammi 202153min

This has been an incredible year for scientific advance and collaboration, epitomised by the roll out of vaccines that didn’t exist a year ago, against a virus that no one had ever heard of . And yet at the same time its been a year of incredible frustration. We are stil largely using the same methods to counter the virus that were used in past pandemics, going back a hundred years. Here we look back at key the findings on who is most susceptible and why, and ask how to improve the strategies for reducing transmission. As regular listeners may recall, CrowdScience has delved into the strange world of fungi before, as we dug down into the forest floor to reveal how plants and trees are connected to the vast mycelial network known as the “wood wide web”. But what makes this network possible and how might it have evolved? Fungi are incredible clever, or at least , it appears that they’re capable of displaying complex behaviour that gives them the appearance of intelligence. In this episode, we speak to fungal ecologist and author of a new book, Merlin Sheldrake, about fungal “brains”, the evolution of magic mushrooms and zombie insects – the astonishing way certain fungi can take over the bodies of ants and wasps in order to sow their spores above ground.(Image: Getty Images)

3 Tammi 202152min

In our first programme of the year, we gathered a group of scientific experts directly involved in analysing the structure and impact of the SARS- Cov-2 coronavirus. There were concerns over the emergence of two new variants, Alfa and Beta, especially whether these variants might spread more quickly or outmanoeuvre the suite of new vaccines that were about to be rolled out. And now with Omicron, the same questions are being asked about this variant’s ability to spread and overcome our defences. We’ve invited the same scientists back to give us their assessment of our journey with Covid 19 over the past year and discuss their findings on Omicron.Featuring: Ravi Gupta Professor of Clinical Microbiology at the University of Cambridge Tulio De Oliveria Professor on Bioinformatics, Stellenbosch University, South Africa Dr. Allie Greaney From the Medical Scientist Training Program at the University of Washington School of Medicine And Professor Jeremy Luban from the Broad Institute of MIT and Harvard Should you wash your eggs? Well, believe it or not, there is quite an international debate about this question from CrowdScience listener Susan. In Canada, where Susan grew up, commercially sold eggs are washed before they reach stores, whereas in the UK where she is now living they are not. So what is best to avoid contamination?It’s one of a number of egg-themed questions that CrowdScience tries to crack in this episode. One of our presenters, Marnie Chesterton, heads over to Susan’s home in London to cook some eggs and explore other egg cooking questions from our listeners, such as what is the science behind frying an egg without it sticking to the pan and why are some boiled eggs harder to shell than others?Meanwhile, this episode’s other presenter, Anand Jagatia, explores questions about eggs after they have hatched. He investigates a case of curious chicken behaviour sent in by listener Laurie, as well as working out how a cuckoo knows it’s a cuckoo when it’s been raised in another bird’s nest.Featuring: Dr. Vincent Guyonnet, Dr. Valérie Lechevalier, Dr. Siobhan Abeyesinghe and Dr. Ros Gloag(Image:Getty Images)

2 Tammi 20211h 7min

It was the end of December 2019 when reports of a new flu like infection first came out of China. Within weeks millions of people were in lockdown as the virus took hold around the world.In this programme we look back and revisit the scientists who were ready, those who had been studying bat coronaviruses and warning of their pandemic potential. The scientific response was immediate. The coronavirus tests now used across the world were being developed within a few hours of news of the outbreak in China, and the vaccines we now have licenced for use began to be formulated just a few days later.At Christmas, is there a better gift than knowledge? CrowdScience has cooked up its own version of 'secret Santa', with members of the team setting one another the challenge of answering surprising questions from all over the world.Are humans the only animals to exercise? Can you get colder than absolute zero? Why are sounds louder at night? When it comes to food dropped on the floor, is there such thing as the "three-second rule"? And, does honey really have healing properties?Producers and presenters from the CrowdScience team speak to all manner of experts, from zoologists through to material scientists, to find the answers.(Image: Getty Images)

27 Joulu 202053min

This week the UK Health secretary raised concerns over a new variant of SARS- CoV-2 currently spreading across Europe. Viruses mutate all the time so it’s no surprise that a new form of the one causing Covid -19 would emerge. However, virologist Ravi Gupta who analysed the new strain says we need to be weary in case future strains mutate in ways that could overcome vaccines.Immunologist Akiko Iwasaki is part of a team looking at the impact of Covid -19 on our immune system. Her research has uncovered autoantibodies linked to infection with the virus. These are responsible for a number of autoimmune diseases. The finding goes some way to explaining the symptoms seen by some people long after a Covid -19 infection.And how clever are ravens? According to behavioural scientist Simone Pika at the Max Planck Institute for Ornithology in many ways they are up there with chimps or young children. She found they performed well in tests designed for primates.Following the dinosaur destroying meteor strike where was the best place for life to develop a new? Geologists, David Kring and Tim Bralower, think they’ve found the answer hidden in plain sight.CrowdScience listener Simon has a problem. He’s always bumping into things, dropping tools and knocking stuff over. And he’s sick of it. He wants to know what is going on. Was he born like this? Or is it contagious? And most importantly, can he doing anything about it or is he going to be the proverbial ‘bull in a china shop’ for the rest of his life?Host Anand Jagatia gets on the case, investigating the complex coordination needed for the simplest movements, like throwing a ball and catching it. With help from Dr Andrew Green, an exercise physiologist from Johannesburg University, he delves into our secret “sixth sense” – proprioception, which helps us locate our limbs without looking. Anand discovers that an easy task, like kicking a football, needs multiple parts of the brain to coordinate in order to work smoothly. Assistant Professor Jessica Bernard from Texas AMU studies the brain, particularly the cerebellum, a part that controls smooth movements. Dr Bernard explains how tiny glitches and larger lesions in different parts of the brain can make us clumsy in different ways. And how we use our thinking powers to stay balanced; a reason why, as your memory goes with old age, you’re more prone to falling over.Our listener is not alone. Around the world, there is an under- diagnosed condition that affects millions of us. Developmental Coordination Disorder (DCD), also known as dyspraxia is a motor coordination condition that affects 5% of the global population. As Professor Amanda Kirby from the University of South Wales and CEO of Do-It solutions explains, if you can’t tie shoelaces, catch a ball and your handwriting is awful, there’s a chance that you have DCD. There’s a large genetic component, so you are likely to come from a clumsy family.There’s no cure for DCD/Dyspraxia but all of us are capable of becoming better at a chosen task, and there’s a common pathway to mastery, whether that’s bike mechanics or open heart surgery. Professor Roger Kneebone is the author of Becoming Expert, and he talks to Simon about possible solutions to clumsiness, including accepting and living with it.[IMAGE: Getty Images]

20 Joulu 20201h 7min

Pictures of coffins and mass graves seen by satellites showed that Manaus has been badly affected by Covid- 19. Now analysis of blood samples shows the extent to which the virus took hold in the Amazon city earlier this year. Investigators Ester Sabino and Lewis Buss from Brazil’s University of Sao Paulo discuss how and why the virus spread.Humanity has been modifying the environment for millennia, but have we now reached a point where it’s all too much? An analysis by Emily Elhacham from Tel Aviv University shows the amount of stuff produced by humanity, from plastics to buildings now has a greater mass than all natural biomass on the planet.And China has been to the moon. Space watcher Andrew Jones tells us how the robotic mission mimics the manned missions of the 1960s and 70s.The space between stars is usually measured in light years, but this makes it less easy to acknowledge the true scale of the distance. Even the closest star system to Earth, Proxima Centauri, is 4.2 light years or 40.13 trillion kilometres from Earth. If we are ever going to bridge the gap between the stars, we will have to have some very fast spaceships, with extremely reliable, long-lasting technology on board.So does science allow for these spacecraft to exist? That’s what listener Allan wants to know, and to find out, Presenter Anand Jagatia speaks with Tracy Drain, a systems engineer at NASA JPL responsible for overseeing the development and missions of multiple unmanned interplanetary probes including some around Jupiter and Mars. She tells us the challenges involved with simply keeping our spacecraft working for the long-haul.Even if we can overcome issues of wear and tear over time, powering a ship to other star systems will not be easy. Today’s chemical rockets are too inefficient for the job, so we speak with Rachel Moloney, a researcher in electric propulsion to ask if this relatively new technology could power ships through interstellar space.Faster than light travel is the solution most often found in Science Fiction, but it goes against Einstein’s laws of relativity. Is there a way around it? Theoretical physicist Professor Miguel Alcubierre thinks there may be, and he describes the way a spaceship may be able to create a bubble of spacetime around itself to move faster than light without breaking these fixed laws. But there’s a catch... (Image: Getty Images)

13 Joulu 202055min

This year’s Atlantic hurricane season has seen a new record for severe storms says Climatologist Michael Mann. He says warming oceans are one of the drivers.And Australia has seen spring temperatures hit new highs. Climate scientist Sarah Perkins – Kirkpatrick says it’s all the more remarkable as weather patterns are currently in a cycle associated with cooler temperatures.Where exactly did SARS- COV-2 emerge from? That’s one of the questions for a WHO fact-finding mission to China looking into the origins of the Virus. Peter Daszak has worked with Chinese scientists for many years, looking for bat viruses with the potential to jump to humans. He tells us how the mission hopes to map out the event which led to the initial spread of the virus.And the Japanese Hayabusa2 space probe is due to return to earth. Masaki Fujimoto Deputy director of the Japanese Space Agency JAXA, tell us what to expect when a cargo of material from a distant asteroid lands in the Australian desert. From dumping raw sewage into rivers to littering the streets with our trash, humans don’t have a great track record when it comes to dealing with our waste. It’s something that CrowdScience listener and civil engineer Marc has noticed: he wonders if humans are particularly prone to messing up our surroundings, while other species are instinctively more hygienic and well-organised.Aasre we, by nature, really less clean and tidy than other animals? Farming and technology have allowed us to live more densely and generate more rubbish - maybe our cleaning instincts just aren’t up to the vast quantities of waste we spew out? CrowdScience digs into the past to see if early human rubbish heaps can turn up any answers. We follow a sewer down to the River Thames to hear about The Great Stink of Victorian London; turn to ants for housekeeping inspiration; and find out how to raise hygiene standards by tapping into our feelings of disgust and our desire to follow rules.(Image: Getty Images)

8 Joulu 20201h 6min

While developing new treatments drug companies usually release little useful information on how the clinical trials are progressing. However with the world’s attention on potential vaccines against Covid -19, the usually dull data on the progression of each trial step is subject to huge scrutiny. It doesn’t help to clarify things says epidemiologist Nicole Basta when that data raises questions about the rigour of the trial itself. This seems to be what happened with the latest Astra Zeneca, and Oxford University trial – where the best results were reportedly due to a mistake. The link between locust plagues and extreme weather was demonstrated once again when cyclone Gati hit Somalia – dumping 2 years worth of rain in just a few days. This creates a perfect environment for locusts to breed to plague proportions. And this will be the third time in as many years that cyclones will trigger such an effect says Keith Cressman from the UNFAO. However thanks to the previous recent locust plagues in East Africa the countries most in line for this returning locust storm are better prepared this time.A study of tree rings from Greater Mongolia suggests the region is now drying out rapidly, the past 20 years have been drier than the past thousand says climate scientist Hans Liderholm. This points to potential desertification in coming years.And the death of a scientific icon. The Arecibo observatory, featured in the films ‘Goldeneye’ and ‘Contact’, and responsible for the Nobel Prize winning detection of gravitational waves is facing demolition. Sitting in a crater in the jungles of Puerto Rico this 57 year old radio telescope dish has suffered severe storm damage and is in danger of collapse. Astronomer Anne Virkki, who works at the telescope and science writer Shannon Stirone explain its significance.This year, dramatic wildfires wreaked havoc across the globe from Australia to Siberia. CrowdScience listener Melissa wants to know the extent to which climate change is a factor in blazes that appear to be increasing in both frequency and intensity.Presenter Anand Jagatia hears how scientists use alternative worlds in computer models, to understand the role that global warming plays. After Siberia’s hottest ever year on record, he discovers the impact of increasing temperatures on boreal forests – and how they could help release huge stocks of carbon that has been stored in the soil. But is there anything we can do to prevent this happening? He visits the UK’s Peak District region, where conservationists are re-wilding a massive area with a special species of moss, which may offer a solution to an increase in infernos.(Image: Credit: Getty Images)

29 Marras 20201h 4min