E140: LK-99, Sclerotic establishments, Fitch downgrades US debt, Trump indicted... again

(0:00) Bestie intros! (0:53) LK-99 breakdown (24:39) Funding landscape for breakthrough science, sclerotic establishments, boomer incumbents (46:04) Fitch downgrades US debt rating (1:09:12) Trump's newest indictment Follow the besties: }https://twitter.com/chamath }https://linktr.ee/calacanis }https://twitter.com/DavidSacks }https://twitter.com/friedberg Follow the pod: }https://twitter.com/theallinpod }https://linktr.ee/allinpodcast Intro Music Credit: }https://rb.gy/tppkzl }https://twitter.com/yung_spielburg Intro Video Credit: }https://twitter.com/TheZachEffect Referenced in the show: }https://arxiv.org/ftp/arxiv/papers/2307/2307.12008.pdf }https://arxiv.org/pdf/2307.12037.pdf }https://manifold.markets/QuantumObserver/will-the-lk99-room-temp-ambient-pre?r=RWxpZXplcll1ZGtvd3NreQ }https://twitter.com/667keos/status/1686490898480173056 }https://twitter.com/iris_IGB/status/1685731177523449856 }https://twitter.com/VCBrags/status/1684591950387716097 }https://stanforddaily.com/2023/07/19/stanford-president-resigns-over-manipulated-research-will-retract-at-least-3-papers }https://www.socialcapital.com/ideas/2021-annual-letter }https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext }https://www.bloomberg.com/news/articles/2023-07-24/sam-altman-valley-vcs-bet-48-million-on-blood-testing-startup }https://www.fitchratings.com/research/sovereigns/fitch-downgrades-united-states-long-term-ratings-to-aa-from-aaa-outlook-stable-01-08-2023 }https://www.npr.org/2023/08/02/1178215888/fitch-downgrade-credit-rating-deficits-debt-economy }https://twitter.com/BillAckman/status/1686906272937869312 }https://home.treasury.gov/news/press-releases/jy1670 }https://www.washingtonpost.com/business/2023/07/22/gop-social-security-trump-rivals-cuts }https://www.commondreams.org/news/republicans-cut-social-security }https://sgp.fas.org/crs/misc/RS22331.pdf }https://fred.stlouisfed.org/series/MORTGAGE30US }https://fred.stlouisfed.org/series/UNRATE }https://fred.stlouisfed.org/series/JTSJOL }https://apnews.com/trump-election-2020-indictment }https://apnews.com/article/trump-indicted-jan-6-investigation-special-counsel-debb59bb7a4d9f93f7e2dace01feccdc }https://projects.fivethirtyeight.com/polls/president-primary-r/2024/national }https://www.reuters.com/world/us/new-defendant-added-trump-classified-documents-case-court-papers-2023-07-27 }https://www.nytimes.com/2023/08/03/briefing/trump-indictment.html }https://twitter.com/mtracey/status/1686843918317486081