Faster Science, Better Drugs
Can we make science as fast as software? In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, ...
15 Sep 202556min
Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy
In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, ...
12 Sep 20251h 35min
Inside the $13T Mortgage Machine
The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software. In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend...
11 Sep 202554min
Chris Dixon on How to Build Networks, Movements, and AI-Native Products
Why do some consumer products explode into networks that reshape the internet, while others fade away?Today on the podcast, a16z general partners Anish Acharya and Chris Dixon take on that question. A...
10 Sep 202542min
Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics
What happens when AI collides with salesmanship, streaming-era sports, and healthcare?In this episode, Erik Torenberg is joined by Mark Cuban, entrepreneur, Dallas Mavericks co-owner, and founder of C...
9 Sep 20251h 1min
The Little Tech Agenda for AI
Who’s speaking up for startups in Washington, D.C.?In this episode, Matt Perault (Head of AI Policy, a16z) and Collin McCune (Head of Government Affairs, a16z) unpack the “Little Tech Agenda” for AI- ...
8 Sep 202557min
Building APIs for Developers and AI Agents
Stainless founder Alex Rattray joins a16z partner Jennifer Li to talk about the future of APIs, SDKs, and the rise of MCP (Model Context Protocol). Drawing on his experience at Stripe—where he helped ...
6 Sep 202526min
How to Be Free: Shaka Senghor, Oprah Winfrey, Ben Horowitz
Taken from The Oprah Podcast, this special episode brings together Shaka Senghor, a16z cofounder Ben Horowitz, and Oprah Winfrey for a powerful conversation on resilience and transformation.Shaka, a r...
5 Sep 202536min
