Big Ideas 2026: Physical AI and the Industrial Stack
The a16z Show25 Des 2025

Big Ideas 2026: Physical AI and the Industrial Stack

AI is moving into the physical economy.

In this episode of Big Ideas 2026, we explore what changes when AI leaves the screen and becomes part of factories, construction sites, supply chains, and critical infrastructure. When the product is physical, reliability matters, real-world constraints appear quickly, and the advantage shifts from standalone software to end-to-end systems.

You will hear from Erin Price-Wright on factory-first principles, Ryan McEntush on the electro-industrial stack, Zabie Elmgren on physical observability, and Will Bitsky on why data, not compute, determines who wins.

Together, these ideas define what physical AI really means: not smarter chat, but deployable systems built for the real world, grounded in new operating models, industrial infrastructure, and defensible data collection.

Resources:

Follow Ryan McEntush on X: https://x.com/rmcentush

Follow Erin Price-Wright on X: https://x.com/espricewright

Follow Zabie Elmgren on X: https://x.com/zabie_e

Follow Will Bitsky on X: https://x.com/willbitsky

Read more all of our 2026 Big Ideas

Part 1: https://a16z.com/newsletter/big-ideas-2026-part-1

Part 2: https://a16z.com/newsletter/big-ideas-2026-part-2/

Part 3: https://a16z.com/newsletter/big-ideas-2026-part-3/

Stay Updated:

If you enjoyed this episode, be sure to like, subscribe, and share with your friends!

Find a16z on X: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX

Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711

Follow our host: https://x.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Stay Updated:

Find a16z on YouTube: YouTube

Find a16z on X

Find a16z on LinkedIn

Listen to the a16z Show on Spotify

Listen to the a16z Show on Apple Podcasts

Follow our host: https://twitter.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episoder(1000)

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

Jack Neel speaks with Amjad Masad, CEO at Replit, about how AI is making it easier than ever to build and ship software without a technical background. They discuss Replit's rise from a browser-based ...

15 Apr 1h 39min

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software

Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI has rewritten the fundamental rules of s...

14 Apr 29min

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Building Agents at Home: Parenting, Work, and Benevolent Neglect

Katherine Boyle and Sarah Wang speak with Jesse Genet, a startup founder and family builder, about building 11 AI agents while homeschooling four young children. Jesse runs agents across roles ranging...

13 Apr 54min

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

What Running Windows at Microsoft Taught Steven Sinofsky About Apple

Theo Jaffee speaks with Steven Sinofsky, board partner at a16z and former president of the Windows division at Microsoft, about Apple's 50th anniversary, the cultural differences that separated Apple ...

10 Apr 31min

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate

Eddy Lazzarin speaks with Vitalik Buterin, founder of Ethereum, and Guillaume Verdon, founder and CEO of Extropic, about whether AI progress can or should be steered, the risks of concentrated power, ...

9 Apr 1h 39min

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They discuss why coding agents succe...

8 Apr 59min

Balaji on Why AI Raises the Cost of Verification

Balaji on Why AI Raises the Cost of Verification

a16z general partner Erik Torenberg speaks with Balaji Srinivasan, angel investor and entrepreneur, about why AI simultaneously reduces the cost of creation and increases the cost of verification, and...

7 Apr 1h 7min

Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Peter Yang on Small Teams, Coding Agents, and Why Human Ambition Has No Ceiling

Anish Acharya speaks with Peter Yang, creator and product lead at Roblox, about how personal AI agents are replacing the apps we open every day, why coding agents feel like slot machines, and what hap...

6 Apr 28min

Populært innen Business og økonomi

stopp-verden
dine-penger-pengeradet
lydartikler-fra-aftenposten
e24-podden
rss-penger-polser-og-politikk
rss-borsmorgen-okonominyhetene
pengepodden-2
pengesnakk
rss-politisk-preik
finansredaksjonen
livet-pa-veien-med-jan-erik-larssen
morgenkaffen-med-finansavisen
utbytte
tid-er-penger-en-podcast-med-peter-warren
stormkast-med-valebrokk-stordalen
rss-markedspuls-2
lederpodden
rss-sunn-okonomi
rss-pa-konto
rss-fa-makro