Epidemiology, Big Data, and Biologics in Pregnancy

Episode transcript and more information at: https://bit.ly/AIBD198

What does a pregnant woman do when they need a biologic medication, but pregnancy isn't included in drug trials? Dr. Sonia Grandi and Dr. Christina Longo talk to Amber Tresca about the BIONIC study, a groundbreaking project using decades of real-world data to understand how biologics affect a pregnant woman and her baby. The BIONIC study is designed to empower patients to make confident, evidence-based decisions about their own health and their children's future.

Timestamps

• 00:00 – Introduction to Dr. Sonia Grandi and Dr. Christina Longo.
• 04:14 – What exactly is an Epidemiologist?
• 06:33 – Why childhood asthma research led to the BIONIC Study.
• 11:05 – Why children and pregnant women are historically excluded from trials.
• 13:00 – Defining "Remission" in children: Why it's more than just labs.
• 17:01 – The BIONIC Study explained: Safety and biologics in pregnancy.
• 22:04 – The Patient Advisory Committee: Why lived experience matters.
• 25:52 – The "Grind" of Research Funding: How projects actually get built.
• 32:21 – Fun & Hobbies: Puzzles, running, and the "BIONIC" spirit.

Find Sonia Grandi, MSc, PhD at:

• The Hospital for Sick Children (SickKids): Sonia Grandi, MSc, PhD
• Dalla Lana School of Public Health: Sonia Grandi, MSc, PhD
• Lab: IMPOWER Lab at The Hospital for Sick Children (SickKids)
• LinkedIn: @sonia-grandi

Find Cristina Longo , PhD at:

• Université de Montréal: Cristina Longo , PhD
• CHU Sainte-Justine: Cristina Longo , PhD
• LinkedIn: @cristina-longo-67656040

Find Amber J Tresca at:

• AboutIBD.com: About IBD
• Verywell Health: Verywell Health
• Facebook: @aboutIBD
• Twitter: @aboutIBD
• Instagram: @about_IBD
• YouTube: @AboutIBD
• Threads: @about_ibd

Find Mac Cooney (mix, sound design, and theme music) at:

• Facebook: @maccooneycomposer
• Instagram: @maccooneycomposer
• YouTube: @MacCooneyComposer
• Web: Cooney Studio
• Theme music, IBD Dance Party, is from ©Cooney Studio.

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