How to Quickly Spot and Manage Psoriasis Comorbidities

What's the best way to screen for common comorbidities in patients with psoriasis, and how do the experts respond when clues of systemic disease show up?

Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/ca8/p04/podcast-psoriasis-s1-ep2-2026a1000560). The topics and discussions are planned, produced, and reviewed independently of our advertiser. This podcast is intended only for US healthcare professionals.

Resources

Psoriasis https://emedicine.medscape.com/article/1943419-overview#a6

Axial Psoriatic Arthritis: An Update for Dermatologists https://www.jaad.org/article/S0190-9622(20)30959-2/fulltext

Psoriatic Arthritis https://emedicine.medscape.com/article/2196539-overview

Psoriatic Arthritis: State of the Art Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297592/pdf/clinmed-17-1-65.pdf

Joint American Academy of Dermatology–National Psoriasis Foundation Guidelines of Care for the Management of Psoriasis With Systemic Nonbiologic Therapies https://www.jaad.org/article/S0190-9622(20)30284-X/fulltext

Axial Spondyloarthritis https://ard.bmj.com/content/80/12/1511.long

Use of IL-23 Inhibitors for the Treatment of Plaque Psoriasis and Psoriatic Arthritis: A Comprehensive Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727454/pdf/40257\_2020\_Article\_578.pdf

Risankizumab, an IL-23 inhibitor, for Ankylosing Spondylitis: Results of a Randomized, Double-blind, Placebo-Controlled, Proof-of-concept, Dose-Finding Phase 2 Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104676/pdf/annrheumdis-2018-213328.pdf

Axial Involvement in Psoriatic Arthritis Cohort (AXIS): The Protocol of a Joint Project of the Assessment of SpondyloArthritis International Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721378/pdf/10.1177\_1759720X211057975.pdf

Three Multicenter, Randomized, Double-blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis https://onlinelibrary.wiley.com/doi/10.1002/art.40728

Efficacy of Guselkumab on Axial Involvement in Patients With Active Psoriatic Arthritis and Sacroiliitis: A Post-Hoc Analysis of the Phase 3 DISCOVER-1 and DISCOVER-2 Studies https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(21)00105-3/fulltext

Efficacy and Safety of Ustekinumab in Psoriatic Arthritis Patients With Peripheral Arthritis and Physician-Reported Spondylitis: Post-hoc Analyses From Two Phase III, Multicentre, Double-blind, Placebo-Controlled Studies (PSUMMIT-1/PSUMMIT-2) https://ard.bmj.com/content/75/11/1984.long

BASDAI Calculator https://qxmd.com/calculate/calculator\_299/basdai

Effectiveness, Costs and Cost-effectiveness of Chiropractic Care and Physiotherapy Compared With Information and Advice in the Treatment of Non-specific Chronic Low Back Pain: Study Protocol for a Randomised Controlled Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741874/pdf/13063\_2017\_Article\_2351.pdf

Axial Involvement in Psoriatic Arthritis: An Update for Rheumatologists https://www.sciencedirect.com/science/article/pii/S0049017221001190?via%3Dihub

Dactylitis: A Hallmark of Psoriatic Arthritis https://www.sciencedirect.com/science/article/pii/S0049017217306261?via%3Dihub

Psoriasis Workup https://emedicine.medscape.com/article/1943419-workup#c2

Treatment Guidelines in Psoriatic Arthritis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065461/pdf/kez383.pdf

Risk of Myocardial Infarction in Patients With Psoriasis https://jamanetwork.com/journals/jama/fullarticle/203598

Cardiovascular Disease Prevention for Psoriasis and Psoriatic Arthritis (CP3) https://www.med.upenn.edu/gelfand/research.html

Primary Care-Based Screening for Cardiovascular Risk Factors in Patients With Psoriasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113692/pdf/BJD-175-348.pdf

Psoriasis: Comorbidities https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252780/pdf/JDE-48-732.pdf

Changing Health Behaviours in Rheumatology: An Introduction to Behavioural Economics https://www.nature.com/articles/s41584-019-0336-1

The Influence of Body Weight of Patients With Chronic Plaque Psoriasis on Biological Treatment Response https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262805/

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