In Silico Trials for Off-Label Use and Equitable Evidence

In Silico Trials for Off-Label Use and Equitable Evidence

Can virtual patients revolutionise medical device testing? Our latest episode dives into groundbreaking in silico trials of the Pipeline Embolization Device for brain aneurysms. We'll explore how anatomical variations impact treatment success, and why this matters for equitable care. Join us to discover how computer simulations are paving the way for safer, more inclusive medical innovations. It's not just code – it's about saving lives fairly.

MacRaild M, Sarrami-Foroushani A, Song S, Liu Q, Kelly C, Ravikumar N, Patankar T, Lassila T, Taylor ZA, Frangi AF. Off-label in-silico flow diverter performance assessment in posterior communicating artery aneurysms. J Neurointerv Surg. 2024 Oct 31:jnis-2024-022000. doi: 10.1136/jnis-2024-022000.

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Episoder(43)

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Join us for an eye-opening exploration of how virtual patient data is revolutionising paediatric clinical trials. In our upcoming episode, we delve into groundbreaking research that addresses one of h...

30 Jun 202528min

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

This episode explores groundbreaking research from Boston Children's Hospital and Harvard Medical School that demonstrates how multiphysiologic state computational fluid dynamics (CFD) modelling is tr...

23 Jun 202522min

Future-Proofing the UK Life Sciences Sector

Future-Proofing the UK Life Sciences Sector

Are you prepared for the seismic shift transforming UK life sciences careers? This latest "In Silico Trials, Real Impacts!" episode reveals how AI and in silico technologies are creating unprecedented...

16 Jun 202517min

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioni...

9 Jun 202532min

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Is simplicity always the smartest choice in science? Or could complexity be the key to groundbreaking discoveries? This episode explores the evolving role of simplicity and complexity in scientific mo...

2 Jun 202527min

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Could computer simulations redefine diabetes care? In this episode, we focus on a real medical product and the role of in silico trials in the transition from the Medtronic Guardian Sensor 3 to the Gu...

25 Mai 202515min

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance o...

19 Mai 202516min

What Underpins Model Credibility? Three Philosophical Perspectives

What Underpins Model Credibility? Three Philosophical Perspectives

How do philosophers of science think about model evaluation? Dive deep into the crucial process of model evaluation, a fundamental step in digital science that determines the effectiveness and precisi...

12 Mai 202519min

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