Probability & Patients: The Stochastic Science Behind In Silico Trial Breakthroughs

Probability & Patients: The Stochastic Science Behind In Silico Trial Breakthroughs

𝗪𝗵𝗮𝘁 𝗶𝗳 𝘁𝗵𝗲 𝗻𝗲𝘅𝘁 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝘁𝗿𝗶𝗮𝗹 𝗯𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝘀 𝗮𝗹𝗿𝗲𝗮𝗱𝘆 𝗶𝗻 𝘆𝗼𝘂𝗿 𝗰𝗼𝗺𝗽𝘂𝘁𝗲𝗿? This episode explores the fascinating world of virtual patient models and stochastic engineering, unveiling how digital simulations are revolutionising healthcare clinical trials. Discover how simulated trials using sophisticated virtual patient models—complete with variations in age, body size, and disease progression—are introducing groundbreaking innovations in patient care.

We delve into stochastic engineering models that cleverly integrate uncertainty into device design, offering more precise and realistic predictions of clinical outcomes. Learn about the power prior method—a dynamic approach to combining digital and real-world evidence in clinical trials, enhancing efficiency and accelerating device delivery to patients whilst maintaining rigorous safety and accuracy standards.

Join us for an illuminating discussion at the cutting edge of healthcare innovation, where virtual modelling meets real-world patient impact.

Haddad T, Himes A, Thompson L, Irony T, Nair R; MDIC Computer Modeling and Simulation Working Group Participants. Incorporation of stochastic engineering models as prior information in Bayesian medical device trials. J Biopharm Stat. 2017;27(6):1089-1103.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(43)

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Join us for an eye-opening exploration of how virtual patient data is revolutionising paediatric clinical trials. In our upcoming episode, we delve into groundbreaking research that addresses one of h...

30 Jun 202528min

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

This episode explores groundbreaking research from Boston Children's Hospital and Harvard Medical School that demonstrates how multiphysiologic state computational fluid dynamics (CFD) modelling is tr...

23 Jun 202522min

Future-Proofing the UK Life Sciences Sector

Future-Proofing the UK Life Sciences Sector

Are you prepared for the seismic shift transforming UK life sciences careers? This latest "In Silico Trials, Real Impacts!" episode reveals how AI and in silico technologies are creating unprecedented...

16 Jun 202517min

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioni...

9 Jun 202532min

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Is simplicity always the smartest choice in science? Or could complexity be the key to groundbreaking discoveries? This episode explores the evolving role of simplicity and complexity in scientific mo...

2 Jun 202527min

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Could computer simulations redefine diabetes care? In this episode, we focus on a real medical product and the role of in silico trials in the transition from the Medtronic Guardian Sensor 3 to the Gu...

25 Mai 202515min

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance o...

19 Mai 202516min

What Underpins Model Credibility? Three Philosophical Perspectives

What Underpins Model Credibility? Three Philosophical Perspectives

How do philosophers of science think about model evaluation? Dive deep into the crucial process of model evaluation, a fundamental step in digital science that determines the effectiveness and precisi...

12 Mai 202519min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
jss
liberal-halvtime
rekommandert
forskningno
sinnsyn
villmarksliv
tomprat-med-gunnar-tjomlid
smart-forklart
dekodet-2
rss-overskuddsliv
rss-nysgjerrige-norge
fjellsportpodden
rss-inn-til-kjernen-med-sunniva-rose
noen-har-snakket-sammen
rss-paradigmepodden
vett-og-vitenskap-med-gaute-einevoll
rss-skogkurs-podden
kvinnehelsepodden